Motif ID: Rxrb

Z-value: 0.839


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032071_34032196-0.801.2e-06Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_118052235 3.250 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr5_-_116422858 2.736 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr18_+_57142782 2.696 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr6_-_23248264 2.544 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr4_-_117178726 2.349 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr10_-_88146867 2.332 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein



chr11_-_40733373 2.188 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr10_+_93641041 1.928 ENSMUST00000020204.4
 Ntn4
netrin 4
chr4_+_44300876 1.850 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr5_+_47984571 1.756 ENSMUST00000174313.1
 Slit2
slit homolog 2 (Drosophila)
chr5_+_110839973 1.754 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr6_+_113531675 1.749 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr1_+_6487231 1.731 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr1_-_170306332 1.639 ENSMUST00000179801.1
 Gm7694
predicted gene 7694
chr16_+_31663841 1.588 ENSMUST00000115201.1
 Dlg1
discs, large homolog 1 (Drosophila)
chr13_+_44729794 1.576 ENSMUST00000172830.1
 Jarid2
jumonji, AT rich interactive domain 2
chr12_-_98737405 1.564 ENSMUST00000170188.1
 Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr16_+_31663935 1.480 ENSMUST00000100001.3
ENSMUST00000064477.7
 Dlg1

discs, large homolog 1 (Drosophila)

chr11_+_40733936 1.405 ENSMUST00000127382.1
 Nudcd2
NudC domain containing 2
chr1_+_131910458 1.361 ENSMUST00000062264.6
 Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.5 3.1 GO:1903753 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) hard palate development(GO:0060022) negative regulation of p38MAPK cascade(GO:1903753)
0.5 2.7 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.4 2.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 2.4 GO:0043297 apical junction assembly(GO:0043297)
0.5 2.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 2.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 2.0 GO:0051028 mRNA transport(GO:0051028)
0.4 1.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 1.8 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.4 1.8 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.0 1.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 1.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 1.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.4 GO:0010388 cullin deneddylation(GO:0010388)
0.1 1.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.1 1.3 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 1.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.6 3.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.1 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 2.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.7 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.5 GO:0031011 Ino80 complex(GO:0031011)
0.4 1.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.2 GO:0002102 podosome(GO:0002102)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.0 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0016234 inclusion body(GO:0016234)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.7 GO:0043237 laminin-1 binding(GO:0043237)
0.2 3.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.6 3.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 3.1 GO:0008017 microtubule binding(GO:0008017)
0.0 2.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.4 GO:0030553 cGMP binding(GO:0030553)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)