Motif ID: Scrt2

Z-value: 1.548


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.822.6e-07Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

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Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 8.045 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr10_+_56377300 7.376 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr7_-_30973399 7.288 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr7_-_30973464 7.167 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr7_-_30973367 7.110 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr3_+_34649987 6.034 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr9_+_91368811 5.949 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368970 5.910 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr3_+_130180882 5.788 ENSMUST00000106353.1
ENSMUST00000080335.4
 Col25a1

collagen, type XXV, alpha 1

chr16_+_16213318 5.241 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr11_-_100355383 5.115 ENSMUST00000146878.2
 Hap1
huntingtin-associated protein 1
chrX_-_72274747 4.887 ENSMUST00000064780.3
 Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr4_+_98923845 4.564 ENSMUST00000091358.4
 Usp1
ubiquitin specific peptidase 1
chr4_+_98923810 4.335 ENSMUST00000030289.2
 Usp1
ubiquitin specific peptidase 1
chr9_-_27155418 4.300 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr3_-_108840477 4.139 ENSMUST00000106596.3
ENSMUST00000102621.4
 Stxbp3a

syntaxin binding protein 3A

chr4_-_129189600 4.039 ENSMUST00000117497.1
ENSMUST00000117350.1
 S100pbp

S100P binding protein

chr2_-_164443177 3.989 ENSMUST00000017153.3
 Sdc4
syndecan 4
chr4_-_129189512 3.959 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
 S100pbp


S100P binding protein


chr4_-_129189646 3.946 ENSMUST00000106059.1
 S100pbp
S100P binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.2 21.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.5 7.4 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.2 7.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.9 6.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.0 5.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 5.6 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
1.7 5.2 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
1.3 5.1 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 5.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 4.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 4.8 GO:0008105 asymmetric protein localization(GO:0008105)
0.5 4.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.8 4.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.4 4.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 3.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 3.7 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.7 3.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.4 3.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 3.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.7 3.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.6 21.6 GO:0061689 tricellular tight junction(GO:0061689)
0.0 8.8 GO:0098793 presynapse(GO:0098793)
0.7 7.4 GO:0005916 fascia adherens(GO:0005916)
0.1 6.1 GO:0030667 secretory granule membrane(GO:0030667)
0.1 6.0 GO:0005581 collagen trimer(GO:0005581)
0.2 5.9 GO:0043034 costamere(GO:0043034)
1.4 5.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 5.5 GO:0005667 transcription factor complex(GO:0005667)
0.5 5.2 GO:0030057 desmosome(GO:0030057)
0.1 5.1 GO:0005776 autophagosome(GO:0005776)
0.3 4.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.9 4.3 GO:0033010 paranodal junction(GO:0033010)
0.3 3.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 3.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 3.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 2.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.3 2.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 21.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 11.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 11.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.4 7.6 GO:0035198 miRNA binding(GO:0035198)
1.5 7.4 GO:0071253 connexin binding(GO:0071253)
0.0 6.9 GO:0003924 GTPase activity(GO:0003924)
0.1 5.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 5.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
1.1 5.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 5.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 5.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 4.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 4.6 GO:0051015 actin filament binding(GO:0051015)
0.0 4.4 GO:0005516 calmodulin binding(GO:0005516)
2.0 4.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 4.0 GO:0005518 collagen binding(GO:0005518)
0.3 3.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 3.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 3.7 GO:0005178 integrin binding(GO:0005178)
0.3 3.6 GO:0004385 guanylate kinase activity(GO:0004385)