Motif ID: Sin3a

Z-value: 1.213


Transcription factors associated with Sin3a:

Gene SymbolEntrez IDGene Name
Sin3a ENSMUSG00000042557.8 Sin3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sin3amm10_v2_chr9_+_57076343_570763870.644.2e-04Click!


Activity profile for motif Sin3a.

activity profile for motif Sin3a


Sorted Z-values histogram for motif Sin3a

Sorted Z-values for motif Sin3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Sin3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_120476469 12.196 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr3_-_66981279 7.009 ENSMUST00000162098.2
 Shox2
short stature homeobox 2
chr17_+_85621017 6.440 ENSMUST00000162695.2
 Six3
sine oculis-related homeobox 3
chr17_+_85620816 5.834 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr11_-_68386821 5.410 ENSMUST00000021284.3
 Ntn1
netrin 1
chr18_+_64340225 4.486 ENSMUST00000175965.2
ENSMUST00000115145.3
 Onecut2

one cut domain, family member 2

chrX_+_58030999 4.267 ENSMUST00000088631.4
ENSMUST00000088629.3
 Zic3

zinc finger protein of the cerebellum 3

chr7_-_70360593 3.681 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr5_-_106458440 3.304 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr2_-_34372004 3.206 ENSMUST00000113132.2
ENSMUST00000040638.8
 Pbx3

pre B cell leukemia homeobox 3

chr14_-_98169542 3.066 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr14_+_122475397 2.905 ENSMUST00000075888.5
 Zic2
zinc finger protein of the cerebellum 2
chr6_-_39206782 2.755 ENSMUST00000002305.8
 Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr12_+_109453455 2.716 ENSMUST00000109844.4
ENSMUST00000109842.2
ENSMUST00000109843.1
ENSMUST00000109846.4
ENSMUST00000173539.1
ENSMUST00000109841.2
 Dlk1





delta-like 1 homolog (Drosophila)





chr6_+_85587524 2.675 ENSMUST00000072018.5
 Alms1
Alstrom syndrome 1
chr12_+_109452833 2.480 ENSMUST00000056110.8
 Dlk1
delta-like 1 homolog (Drosophila)
chr13_+_72628802 2.428 ENSMUST00000074372.4
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr3_+_66981352 2.370 ENSMUST00000162036.1
 Rsrc1
arginine/serine-rich coiled-coil 1
chr2_+_31640037 2.287 ENSMUST00000113470.2
 Prdm12
PR domain containing 12
chr11_-_68386974 2.206 ENSMUST00000135141.1
 Ntn1
netrin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 554 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.5 13.5 GO:0097402 neuroblast migration(GO:0097402)
1.4 12.2 GO:0060613 fat pad development(GO:0060613)
1.3 7.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.7 7.0 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.5 5.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.4 5.0 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.5 4.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.7 4.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 4.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.7 4.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.6 3.9 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.7 3.7 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.5 3.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 3.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 3.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
1.0 3.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.7 2.9 GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.3 2.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.8 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 2.8 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 200 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 71.7 GO:0005634 nucleus(GO:0005634)
0.0 11.0 GO:0000785 chromatin(GO:0000785)
0.0 10.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 8.3 GO:0005604 basement membrane(GO:0005604)
0.1 6.7 GO:0005814 centriole(GO:0005814)
0.0 5.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.4 GO:0005844 polysome(GO:0005844)
0.1 4.3 GO:0000922 spindle pole(GO:0000922)
0.1 4.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 3.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 3.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.9 GO:0030478 actin cap(GO:0030478)
0.2 2.9 GO:0097470 ribbon synapse(GO:0097470)
0.2 2.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 2.4 GO:0005861 troponin complex(GO:0005861)
0.4 2.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 2.0 GO:0016589 NURF complex(GO:0016589)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 309 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.1 12.6 GO:0003680 AT DNA binding(GO:0003680)
0.6 11.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 6.3 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2 5.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 4.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 4.0 GO:0071837 HMG box domain binding(GO:0071837)
1.3 3.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 3.8 GO:0046790 virion binding(GO:0046790)
0.4 3.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.6 GO:0035064 methylated histone binding(GO:0035064)
0.2 3.5 GO:0070888 E-box binding(GO:0070888)
0.1 3.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 3.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 3.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 3.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 2.8 GO:0035198 miRNA binding(GO:0035198)
0.9 2.7 GO:0097108 hedgehog family protein binding(GO:0097108)