Motif ID: Smad4

Z-value: 0.835


Transcription factors associated with Smad4:

Gene SymbolEntrez IDGene Name
Smad4 ENSMUSG00000024515.7 Smad4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smad4mm10_v2_chr18_-_73703739_737038060.019.5e-01Click!


Activity profile for motif Smad4.

activity profile for motif Smad4


Sorted Z-values histogram for motif Smad4

Sorted Z-values for motif Smad4



Network of associatons between targets according to the STRING database.



First level regulatory network of Smad4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_22042949 2.768 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr7_+_24862193 2.444 ENSMUST00000052897.4
ENSMUST00000170837.2
Gm9844
Gm9844
predicted pseudogene 9844
predicted pseudogene 9844
chr10_-_127534540 2.360 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr13_-_21832194 2.244 ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr1_-_16770138 2.159 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr11_-_95514570 1.953 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr13_+_23581563 1.674 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chr14_-_104467984 1.657 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr13_-_23551648 1.519 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr13_+_23531044 1.499 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr19_+_5740885 1.249 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr13_+_21735055 1.239 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr3_-_96220880 1.157 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr10_+_80150448 1.150 ENSMUST00000153477.1
Midn
midnolin
chr8_+_54954728 1.109 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr4_-_148130678 1.065 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr8_-_109251698 1.051 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr8_-_92356103 0.942 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr19_+_46328179 0.862 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr6_-_72958097 0.828 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr13_-_23934156 0.811 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chrX_+_56779437 0.780 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr3_+_127633134 0.777 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr2_+_32628390 0.765 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr6_+_54040078 0.746 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chr13_+_22043189 0.727 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr5_+_75574916 0.716 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr11_-_33147400 0.702 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr6_-_138422898 0.678 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr4_-_95052170 0.674 ENSMUST00000058555.2
Jun
Jun oncogene
chr5_+_120431770 0.672 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr2_-_173276144 0.659 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr1_-_173367638 0.641 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr4_+_133011506 0.572 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr14_-_54577578 0.566 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr12_+_103314944 0.565 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr5_-_24601961 0.557 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_-_137741102 0.549 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr5_+_30913398 0.519 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr5_+_117841839 0.511 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr5_+_7179299 0.498 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr7_+_101421691 0.497 ENSMUST00000163751.2
ENSMUST00000084894.7
ENSMUST00000166652.1
Pde2a


phosphodiesterase 2A, cGMP-stimulated


chr3_+_88607742 0.491 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr7_+_4690760 0.485 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr17_-_29888570 0.480 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr14_+_57826210 0.475 ENSMUST00000022538.3
Mrp63
mitochondrial ribosomal protein 63
chr7_-_30362772 0.473 ENSMUST00000046351.5
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chrX_+_136270302 0.467 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr17_+_75178797 0.457 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chrX_+_136270253 0.452 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr7_+_45215753 0.448 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr17_+_75178911 0.448 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr15_+_81936911 0.428 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr10_+_80300997 0.410 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr15_+_39076885 0.406 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr1_-_133801031 0.406 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr7_+_83755904 0.406 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr5_+_111417263 0.399 ENSMUST00000094463.4
Mn1
meningioma 1
chr7_+_45216671 0.390 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr11_-_89302545 0.390 ENSMUST00000061728.3
Nog
noggin
chr17_+_72918298 0.390 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr11_+_60699718 0.385 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr19_-_40271506 0.385 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr17_-_25081138 0.373 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr11_-_106159902 0.371 ENSMUST00000064545.4
Limd2
LIM domain containing 2
chr7_+_141216626 0.370 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr11_-_106160708 0.369 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr4_+_128688726 0.354 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr2_+_119547697 0.353 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chr9_+_57940104 0.339 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr11_-_26591729 0.339 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr4_-_134245579 0.338 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr4_+_97772734 0.336 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chrX_-_7898864 0.329 ENSMUST00000154552.1
Pqbp1
polyglutamine binding protein 1
chr11_+_69846610 0.328 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr2_+_155940728 0.322 ENSMUST00000109629.1
Gm15557
predicted gene 15557
chr7_+_119895836 0.312 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr8_-_34146974 0.310 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr11_-_69413675 0.307 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr19_+_4231899 0.306 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr2_-_128967725 0.305 ENSMUST00000099385.2
Gm10762
predicted gene 10762
chr1_+_177445660 0.299 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr11_+_60699758 0.296 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr16_-_55283237 0.292 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr8_+_45658273 0.278 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr6_+_54039558 0.276 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr4_-_134254076 0.270 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr2_+_27079371 0.269 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr18_-_52529692 0.268 ENSMUST00000025409.7
Lox
lysyl oxidase
chr4_-_117178726 0.265 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr8_-_41016749 0.261 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr18_-_52529847 0.260 ENSMUST00000171470.1
Lox
lysyl oxidase
chr17_+_46646225 0.259 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr4_+_126677630 0.255 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr3_-_146839365 0.253 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr1_+_187997835 0.245 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr4_+_127172866 0.242 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr15_+_81936753 0.237 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr6_-_83775767 0.226 ENSMUST00000014892.6
Tex261
testis expressed gene 261
chr2_+_128967383 0.222 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr11_-_106160101 0.220 ENSMUST00000045923.3
Limd2
LIM domain containing 2
chr3_+_68572245 0.218 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr7_+_141949846 0.211 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr11_+_69846665 0.209 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr9_+_21424984 0.209 ENSMUST00000172482.1
ENSMUST00000174050.1
Dnm2

dynamin 2

chrX_+_99136119 0.208 ENSMUST00000052839.6
Efnb1
ephrin B1
chr14_+_12189943 0.206 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr14_-_54554359 0.206 ENSMUST00000022784.8
Haus4
HAUS augmin-like complex, subunit 4
chrX_-_7898950 0.205 ENSMUST00000115655.1
ENSMUST00000156741.1
Pqbp1

polyglutamine binding protein 1

chr1_+_153652943 0.203 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chrX_+_159708593 0.200 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr4_+_116221689 0.200 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr9_-_20898592 0.194 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr4_-_129742275 0.186 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr3_+_96221111 0.182 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chr14_+_64950037 0.182 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr17_-_70851710 0.182 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr19_+_4097392 0.181 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr1_+_187997821 0.180 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr10_+_75589363 0.178 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr6_+_54039935 0.176 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr4_+_116221633 0.174 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chrX_-_136741155 0.168 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr7_-_100855403 0.168 ENSMUST00000156855.1
Relt
RELT tumor necrosis factor receptor
chr15_+_102102926 0.167 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr7_+_141949982 0.164 ENSMUST00000105989.2
ENSMUST00000075528.5
ENSMUST00000174499.1
Brsk2


BR serine/threonine kinase 2


chr19_-_8818924 0.155 ENSMUST00000153281.1
Ttc9c
tetratricopeptide repeat domain 9C
chr9_+_59589288 0.154 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr17_+_24352037 0.153 ENSMUST00000079594.5
Abca3
ATP-binding cassette, sub-family A (ABC1), member 3
chr13_-_115090123 0.149 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr2_+_125136692 0.145 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr18_+_57133065 0.145 ENSMUST00000075770.6
Megf10
multiple EGF-like-domains 10
chr2_+_55437100 0.141 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr12_-_36156781 0.137 ENSMUST00000020856.4
Bzw2
basic leucine zipper and W2 domains 2
chr15_-_103366763 0.135 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr7_+_45785331 0.132 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr18_-_35498856 0.131 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr9_+_61373482 0.130 ENSMUST00000160541.1
ENSMUST00000161207.1
ENSMUST00000159630.1
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr8_+_95825353 0.126 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr2_+_3114220 0.125 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr5_+_19907774 0.119 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_3931789 0.114 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr17_-_35162969 0.113 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr6_-_72958465 0.113 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr7_+_127485221 0.110 ENSMUST00000048896.6
Fbrs
fibrosin
chr14_-_18331855 0.110 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr9_+_61373608 0.104 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr4_+_148130883 0.104 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr9_-_57552760 0.100 ENSMUST00000034856.8
Mpi
mannose phosphate isomerase
chr12_+_13269111 0.098 ENSMUST00000042953.8
Nbas
neuroblastoma amplified sequence
chr11_-_115419917 0.095 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr5_-_24445166 0.093 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr9_-_21852603 0.089 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr11_+_4637734 0.089 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr7_-_126897424 0.089 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr4_+_116221590 0.089 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr9_+_61373219 0.085 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
Tle3





transducin-like enhancer of split 3, homolog of Drosophila E(spl)





chr11_-_3931960 0.084 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chrX_-_150812932 0.077 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr7_-_119895697 0.073 ENSMUST00000059851.6
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr4_+_118621160 0.073 ENSMUST00000147373.1
Ebna1bp2
EBNA1 binding protein 2
chr9_-_49798905 0.072 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr9_+_96895617 0.069 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123
chr6_+_15720654 0.068 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr7_+_123377982 0.065 ENSMUST00000033025.5
Lcmt1
leucine carboxyl methyltransferase 1
chr5_+_92683625 0.058 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr19_-_5295397 0.056 ENSMUST00000025774.9
Sf3b2
splicing factor 3b, subunit 2
chr7_-_45052865 0.056 ENSMUST00000057293.6
Prr12
proline rich 12
chr3_-_116968969 0.054 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr11_+_4160348 0.053 ENSMUST00000002198.3
Sf3a1
splicing factor 3a, subunit 1
chr9_-_49798729 0.049 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr11_+_60104971 0.048 ENSMUST00000064190.6
Rai1
retinoic acid induced 1
chr4_+_42950369 0.047 ENSMUST00000084662.5
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr9_+_106429537 0.043 ENSMUST00000059802.6
Rpl29
ribosomal protein L29
chr5_-_24445254 0.039 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr11_+_115420059 0.039 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chrX_+_150588223 0.036 ENSMUST00000153221.1
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chrX_+_136707976 0.030 ENSMUST00000055104.5
Tceal1
transcription elongation factor A (SII)-like 1
chr10_+_91082940 0.028 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chr15_-_38300693 0.025 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr11_-_102319093 0.022 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf


upstream binding transcription factor, RNA polymerase I


chr5_+_65537267 0.020 ENSMUST00000122141.1
Ube2k
ubiquitin-conjugating enzyme E2K
chrX_+_41401476 0.016 ENSMUST00000165288.1
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr2_+_127247908 0.015 ENSMUST00000035871.8
ENSMUST00000174503.1
ENSMUST00000174288.1
Tmem127


transmembrane protein 127


chr5_+_19907502 0.014 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_25903100 0.007 ENSMUST00000052286.8
Plac9a
placenta specific 9a
chr11_+_115420138 0.006 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr10_-_92164666 0.005 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr10_-_42583628 0.002 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chrX_-_150588071 0.001 ENSMUST00000140207.1
ENSMUST00000112719.1
ENSMUST00000112727.3
ENSMUST00000112721.3
ENSMUST00000026303.9
Apex2




apurinic/apyrimidinic endonuclease 2




chr15_-_93336800 0.001 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 1.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 1.7 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) proprioception(GO:0019230)
0.2 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.7 GO:1905065 hematopoietic stem cell migration(GO:0035701) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.2 0.9 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.2 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.4 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 0.7 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.7 GO:0045657 positive regulation of monocyte differentiation(GO:0045657) cellular response to potassium ion starvation(GO:0051365)
0.1 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.7 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.4 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947) vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.8 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.5 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 4.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0043654 skeletal muscle satellite cell differentiation(GO:0014816) recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.8 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.4 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 1.1 GO:0003407 neural retina development(GO:0003407)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.5 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.5 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.1 11.1 GO:0000786 nucleosome(GO:0000786)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0050436 microfibril binding(GO:0050436)
0.2 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.5 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 1.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 8.2 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0070699 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)