Motif ID: Smarcc1_Fosl1

Z-value: 0.969

Transcription factors associated with Smarcc1_Fosl1:

Gene SymbolEntrez IDGene Name
Fosl1 ENSMUSG00000024912.5 Fosl1
Smarcc1 ENSMUSG00000032481.10 Smarcc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smarcc1mm10_v2_chr9_+_110132015_110132102-0.741.3e-05Click!
Fosl1mm10_v2_chr19_+_5447692_54477110.635.4e-04Click!


Activity profile for motif Smarcc1_Fosl1.

activity profile for motif Smarcc1_Fosl1


Sorted Z-values histogram for motif Smarcc1_Fosl1

Sorted Z-values for motif Smarcc1_Fosl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Smarcc1_Fosl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_33907721 3.462 ENSMUST00000115161.1
ENSMUST00000062289.8
 Bend6

BEN domain containing 6

chr9_-_20728219 3.175 ENSMUST00000034692.7
 Olfm2
olfactomedin 2
chr6_+_17463927 2.509 ENSMUST00000115442.1
 Met
met proto-oncogene
chr7_-_103827922 2.489 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr13_-_54611274 2.382 ENSMUST00000049575.7
 Cltb
clathrin, light polypeptide (Lcb)
chr13_-_54611332 2.316 ENSMUST00000091609.4
 Cltb
clathrin, light polypeptide (Lcb)
chr5_+_117841839 2.289 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr15_-_66812593 2.164 ENSMUST00000100572.3
 Sla
src-like adaptor
chr14_+_65968483 1.983 ENSMUST00000022616.6
 Clu
clusterin
chr1_-_134235420 1.971 ENSMUST00000038191.6
ENSMUST00000086465.4
 Adora1

adenosine A1 receptor

chr6_+_124996681 1.970 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr3_+_55461758 1.916 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr1_+_58210397 1.859 ENSMUST00000040442.5
 Aox4
aldehyde oxidase 4
chr3_-_88503187 1.807 ENSMUST00000120377.1
 Lmna
lamin A
chr2_+_156475844 1.791 ENSMUST00000103135.1
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr2_+_156475803 1.781 ENSMUST00000029155.8
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr6_-_124769548 1.754 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr19_-_59076069 1.722 ENSMUST00000047511.7
ENSMUST00000163821.1
 4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr7_+_126776939 1.710 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr10_-_117282262 1.663 ENSMUST00000092163.7
 Lyz2
lysozyme 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 405 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 4.2 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.4 3.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4 3.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.9 3.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 2.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.7 2.7 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 2.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 2.1 GO:0032060 bleb assembly(GO:0032060)
0.1 2.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.7 2.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.5 2.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 2.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 2.0 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.3 1.9 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.0 1.9 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.3 1.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 167 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 5.2 GO:0097060 synaptic membrane(GO:0097060)
0.4 4.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.6 4.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 4.3 GO:0005604 basement membrane(GO:0005604)
0.0 4.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 3.4 GO:0005638 lamin filament(GO:0005638)
0.0 3.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.9 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 2.6 GO:0005581 collagen trimer(GO:0005581)
0.6 2.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 2.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 2.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 264 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 4.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
1.0 3.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 3.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.6 2.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.8 2.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.8 2.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.8 2.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 2.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 2.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.0 GO:0030552 cAMP binding(GO:0030552)