Motif ID: Sox11

Z-value: 0.290


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_27342726-0.125.5e-01Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_24327415 0.605 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr13_-_41487306 0.543 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr4_-_97584605 0.393 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr9_-_16378231 0.387 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_89909775 0.376 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr4_-_97584612 0.375 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_+_15516489 0.375 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr1_+_82233112 0.345 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr5_+_89027959 0.304 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr5_+_64812336 0.303 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr16_-_50330987 0.284 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr10_-_76110956 0.266 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chrX_+_56786527 0.258 ENSMUST00000144600.1
 Fhl1
four and a half LIM domains 1
chr7_-_73541738 0.250 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr16_-_44558864 0.247 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr16_+_65520503 0.238 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
 Pou1f1


POU domain, class 1, transcription factor 1


chr15_+_76797628 0.229 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr16_-_38341812 0.228 ENSMUST00000114740.2
ENSMUST00000023501.8
 Maats1

MYCBP-associated, testis expressed 1

chr16_-_44558879 0.201 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr13_-_99516537 0.179 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr2_+_15055274 0.177 ENSMUST00000069870.3
 Arl5b
ADP-ribosylation factor-like 5B
chr17_+_35517100 0.172 ENSMUST00000164242.2
ENSMUST00000045956.7
 Cchcr1

coiled-coil alpha-helical rod protein 1

chr10_-_14718191 0.164 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr5_-_131616599 0.157 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr9_+_101074727 0.148 ENSMUST00000085177.3
 Msl2
male-specific lethal 2 homolog (Drosophila)
chr3_+_28805436 0.146 ENSMUST00000043867.5
 Rpl22l1
ribosomal protein L22 like 1
chr5_+_89028035 0.137 ENSMUST00000113216.2
ENSMUST00000134303.1
 Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr11_+_24080664 0.137 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_21848039 0.134 ENSMUST00000098238.2
ENSMUST00000108229.1
 Sfrs18

serine/arginine-rich splicing factor 18

chr5_-_123141067 0.130 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr4_-_43030440 0.130 ENSMUST00000135660.1
 Stoml2
stomatin (Epb7.2)-like 2
chr9_+_52047150 0.100 ENSMUST00000163153.1
 Rdx
radixin
chr7_+_83631959 0.097 ENSMUST00000075418.7
ENSMUST00000117410.1
 Stard5

StAR-related lipid transfer (START) domain containing 5

chrX_-_37104523 0.097 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr11_-_69369377 0.096 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr13_-_84064772 0.094 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr10_+_119992916 0.089 ENSMUST00000105261.2
 Grip1
glutamate receptor interacting protein 1
chr2_-_156111954 0.087 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
 Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr3_+_67430096 0.084 ENSMUST00000077271.6
ENSMUST00000161009.1
 Gfm1

G elongation factor, mitochondrial 1

chr8_-_83442648 0.080 ENSMUST00000167525.1
 Scoc
short coiled-coil protein
chr1_+_44119952 0.077 ENSMUST00000114709.2
 Bivm
basic, immunoglobulin-like variable motif containing
chr14_-_47418407 0.073 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chrM_+_7005 0.070 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr17_-_29007925 0.069 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr5_+_121795034 0.069 ENSMUST00000162327.1
 Atxn2
ataxin 2
chr2_-_86347764 0.066 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr14_-_121698417 0.066 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr7_-_105737376 0.061 ENSMUST00000098148.4
 Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr4_-_123139929 0.058 ENSMUST00000030404.4
 Ppie
peptidylprolyl isomerase E (cyclophilin E)
chr5_-_148552783 0.058 ENSMUST00000079324.7
ENSMUST00000164904.1
 Ubl3

ubiquitin-like 3

chr13_-_113618549 0.057 ENSMUST00000109241.3
 Snx18
sorting nexin 18
chrX_+_85574018 0.055 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr11_-_50292302 0.051 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr9_+_65890237 0.046 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr7_-_55962466 0.043 ENSMUST00000032635.7
ENSMUST00000152649.1
 Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr13_+_40859768 0.040 ENSMUST00000110191.2
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr14_-_52213379 0.034 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr2_+_154548888 0.031 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr2_-_127792467 0.030 ENSMUST00000135091.1
 1500011K16Rik
RIKEN cDNA 1500011K16 gene
chr2_+_157279026 0.030 ENSMUST00000116380.2
 Rpn2
ribophorin II
chr2_-_119662756 0.029 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
 Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr5_+_14514918 0.027 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr2_-_79456750 0.025 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr15_-_81104999 0.022 ENSMUST00000109579.2
 Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr9_+_32116040 0.016 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr1_-_175491130 0.015 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7
chr12_-_54862783 0.006 ENSMUST00000078124.7
 Cfl2
cofilin 2, muscle
chr8_-_34965631 0.004 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr16_+_8830093 0.003 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr11_+_98937669 0.002 ENSMUST00000107475.2
ENSMUST00000068133.3
 Rara

retinoic acid receptor, alpha

chr2_+_157279065 0.002 ENSMUST00000029171.5
 Rpn2
ribophorin II

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)