Motif ID: Sox14

Z-value: 0.805


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_998761930.481.2e-02Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_53779694 2.043 ENSMUST00000030124.3
 Tal2
T cell acute lymphocytic leukemia 2
chr14_-_104467984 1.964 ENSMUST00000053016.8
 Pou4f1
POU domain, class 4, transcription factor 1
chr13_-_14523178 1.798 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr8_+_92357787 1.788 ENSMUST00000034184.10
 Irx5
Iroquois related homeobox 5 (Drosophila)
chr11_+_67586520 1.621 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr11_+_67586675 1.443 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr18_-_43393346 1.302 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr4_+_13751297 1.216 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_101377074 1.159 ENSMUST00000043983.5
 Igsf3
immunoglobulin superfamily, member 3
chr15_-_95528228 1.124 ENSMUST00000075275.2
 Nell2
NEL-like 2
chr12_+_109545390 1.081 ENSMUST00000146701.1
 Meg3
maternally expressed 3
chr4_+_102254739 1.067 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr12_+_109546333 1.058 ENSMUST00000166636.2
 Meg3
maternally expressed 3
chr7_-_19166119 1.057 ENSMUST00000094790.3
 Gipr
gastric inhibitory polypeptide receptor
chr14_-_60197173 1.008 ENSMUST00000131670.1
 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_+_58554799 0.984 ENSMUST00000098676.2
 Gm10657
predicted gene 10657
chr1_-_51941261 0.981 ENSMUST00000097103.3
 Gm8420
predicted gene 8420
chr3_+_55461758 0.969 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr12_+_109546409 0.948 ENSMUST00000143847.1
 Meg3
maternally expressed 3
chr12_+_73997749 0.943 ENSMUST00000110451.2
 Syt16
synaptotagmin XVI

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 3.3 GO:0008360 regulation of cell shape(GO:0008360)
0.4 2.0 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) proprioception(GO:0019230)
0.2 2.0 GO:0021794 thalamus development(GO:0021794)
0.2 1.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 1.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 1.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.5 1.5 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.4 1.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 1.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.1 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 1.1 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 1.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 1.0 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 0.9 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0005884 actin filament(GO:0005884)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0031258 catenin complex(GO:0016342) lamellipodium membrane(GO:0031258)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.5 1.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 1.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.1 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)