Motif ID: Sox15

Z-value: 0.569


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 125 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 2.870 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_49636847 2.591 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr14_-_48662740 2.177 ENSMUST00000122009.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr19_+_55741810 2.151 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr12_-_119238794 1.498 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chr17_-_70851189 1.476 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr10_+_53596936 1.411 ENSMUST00000020004.6
 Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr3_+_131110350 1.309 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr8_+_108714644 1.268 ENSMUST00000043896.8
 Zfhx3
zinc finger homeobox 3
chr12_+_24708984 1.239 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr18_+_11633276 1.199 ENSMUST00000115861.2
 Rbbp8
retinoblastoma binding protein 8
chr1_-_138842429 1.124 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr11_+_88068242 1.119 ENSMUST00000018521.4
 Vezf1
vascular endothelial zinc finger 1
chr1_+_19212054 0.938 ENSMUST00000064976.4
 Tfap2b
transcription factor AP-2 beta
chr3_+_34649987 0.923 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr12_+_52516077 0.915 ENSMUST00000110725.1
 Arhgap5
Rho GTPase activating protein 5
chr8_-_11312731 0.859 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr10_+_17796256 0.820 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr3_-_8964037 0.799 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr12_-_40445754 0.787 ENSMUST00000069692.8
ENSMUST00000069637.7
 Zfp277

zinc finger protein 277


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5 2.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 2.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 1.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724)
0.4 1.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.4 1.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 1.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 1.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 1.1 GO:0001885 endothelial cell development(GO:0001885)
0.3 0.9 GO:0097274 urea homeostasis(GO:0097274)
0.2 0.9 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.9 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.8 GO:2000772 regulation of cellular senescence(GO:2000772)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.7 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 2.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 2.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 1.5 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.2 1.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.9 GO:0035198 miRNA binding(GO:0035198)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.2 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)