Z-value: 2.261
Transcription factors associated with Sox2:
Activity-expression correlation:
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Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 388 entries
Log-likelihood per target Total log-likelihood Term Description
0.6
11.4
GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.7
11.0
GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2
9.1
GO:0030517 negative regulation of axon extension(GO:0030517)
1.2
8.4
GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
2.6
7.9
GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1
7.4
GO:0000045 autophagosome assembly(GO:0000045)
0.2
7.3
GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.8
7.2
GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.6
6.7
GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5
6.4
GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.2
6.1
GO:2001025 positive regulation of response to drug(GO:2001025)
0.4
5.2
GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.9
5.1
GO:0006172 ADP biosynthetic process(GO:0006172)
0.1
4.8
GO:0021954 central nervous system neuron development(GO:0021954)
0.2
4.5
GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.6
4.3
GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1
4.3
GO:0002028 regulation of sodium ion transport(GO:0002028)
1.4
4.1
GO:2000344 positive regulation of acrosome reaction(GO:2000344)
1.0
4.1
GO:0097477 lateral motor column neuron migration(GO:0097477)
0.7
4.0
GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihood Term Description
1.2
11.9
GO:0045298 tubulin complex(GO:0045298)
0.4
10.3
GO:0071565 nBAF complex(GO:0071565)
0.1
9.6
GO:0045202 synapse(GO:0045202)
0.2
8.5
GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1
8.5
GO:0008021 synaptic vesicle(GO:0008021)
2.6
7.9
GO:0033193 Lsd1/2 complex(GO:0033193)
0.1
7.2
GO:0032587 ruffle membrane(GO:0032587)
0.3
6.9
GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1
6.8
GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3
6.7
GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1
6.7
GO:0043204 perikaryon(GO:0043204)
0.3
6.6
GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.6
5.9
GO:0044327 dendritic spine head(GO:0044327)
0.9
5.6
GO:1990635 proximal dendrite(GO:1990635)
0.6
5.6
GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1
5.6
GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1
5.3
GO:0005884 actin filament(GO:0005884)
0.6
5.2
GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.6
5.1
GO:0001520 outer dense fiber(GO:0001520)
0.1
4.9
GO:0000788 nuclear nucleosome(GO:0000788)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 247 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
25.7
GO:0008270 zinc ion binding(GO:0008270)
0.0
16.5
GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1
12.6
GO:0008017 microtubule binding(GO:0008017)
0.2
11.1
GO:0070888 E-box binding(GO:0070888)
0.3
9.6
GO:0030215 semaphorin receptor binding(GO:0030215)
0.1
9.4
GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.4
9.3
GO:0034185 apolipoprotein binding(GO:0034185)
0.4
9.2
GO:0045295 gamma-catenin binding(GO:0045295)
0.4
8.8
GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3
8.5
GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4
8.3
GO:0001784 phosphotyrosine binding(GO:0001784)
0.9
7.2
GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1
7.1
GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1
7.0
GO:0048365 Rac GTPase binding(GO:0048365)
0.2
6.4
GO:0004364 glutathione transferase activity(GO:0004364)
0.4
6.0
GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2
5.3
GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.5
5.1
GO:0004017 adenylate kinase activity(GO:0004017)
0.0
5.1
GO:0005525 GTP binding(GO:0005525)
0.1
5.0
GO:0030552 cAMP binding(GO:0030552)
