Motif ID: Sox30

Z-value: 0.573


Transcription factors associated with Sox30:

Gene SymbolEntrez IDGene Name
Sox30 ENSMUSG00000040489.5 Sox30



Activity profile for motif Sox30.

activity profile for motif Sox30


Sorted Z-values histogram for motif Sox30

Sorted Z-values for motif Sox30



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 5.744 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr6_-_12749193 2.406 ENSMUST00000046121.6
ENSMUST00000172356.1
 Thsd7a

thrombospondin, type I, domain containing 7A

chr10_+_17796256 2.389 ENSMUST00000037964.6
 Txlnb
taxilin beta
chrX_-_134161928 1.755 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr9_+_7764041 1.751 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr14_+_116925379 1.500 ENSMUST00000088483.3
 Gpc6
glypican 6
chr3_+_34649987 1.494 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr13_-_102958084 1.328 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chr10_-_24836165 1.295 ENSMUST00000020169.7
 Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr5_+_92809372 1.222 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr18_-_88927447 1.103 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr1_+_135729147 1.069 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr2_-_58052832 1.008 ENSMUST00000090940.5
 Ermn
ermin, ERM-like protein
chr12_-_99883429 0.961 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr6_-_3494587 0.922 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr10_-_53647080 0.840 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr2_-_101883010 0.840 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr10_-_62792243 0.780 ENSMUST00000020268.5
 Ccar1
cell division cycle and apoptosis regulator 1
chr7_+_90426312 0.756 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89
chr9_-_72111651 0.736 ENSMUST00000185117.1
 Tcf12
transcription factor 12
chr9_-_32541589 0.722 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr8_+_46490968 0.691 ENSMUST00000110372.1
ENSMUST00000130563.1
 Acsl1

acyl-CoA synthetase long-chain family member 1

chr4_-_119190005 0.573 ENSMUST00000138395.1
ENSMUST00000156746.1
 Ermap

erythroblast membrane-associated protein

chr9_-_103480328 0.561 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr2_+_3114220 0.519 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr18_-_62756275 0.474 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr1_+_37997975 0.428 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr6_-_132314757 0.427 ENSMUST00000048686.8
 Prpmp5
proline-rich protein MP5
chr7_+_127800604 0.416 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr19_+_44293676 0.410 ENSMUST00000026221.5
 Scd2
stearoyl-Coenzyme A desaturase 2
chr14_-_19823807 0.401 ENSMUST00000022341.5
 2700060E02Rik
RIKEN cDNA 2700060E02 gene
chr2_-_119787504 0.334 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
 Rpap1


RNA polymerase II associated protein 1


chr4_+_137993445 0.334 ENSMUST00000105831.2
ENSMUST00000084214.5
 Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr9_-_60511003 0.330 ENSMUST00000098660.3
 Thsd4
thrombospondin, type I, domain containing 4
chr3_-_8964037 0.314 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr1_+_10056922 0.276 ENSMUST00000149214.1
 Cspp1
centrosome and spindle pole associated protein 1
chr2_-_65567505 0.265 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_-_115133977 0.186 ENSMUST00000051400.7
 Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr5_-_62765618 0.182 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_+_8674129 0.180 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr5_-_137072254 0.173 ENSMUST00000077523.3
ENSMUST00000041388.4
 Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr11_+_3983636 0.169 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_51261719 0.164 ENSMUST00000130641.1
 Clk4
CDC like kinase 4
chr12_+_8674224 0.162 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr2_-_65567465 0.162 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_+_109343029 0.138 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chr11_+_3983704 0.131 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr4_+_137993016 0.113 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
 Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr15_+_100038635 0.106 ENSMUST00000100203.3
 Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chrX_+_100767719 0.104 ENSMUST00000000901.6
ENSMUST00000113736.2
ENSMUST00000087984.4
 Dlg3


discs, large homolog 3 (Drosophila)


chr16_+_4036942 0.095 ENSMUST00000137748.1
ENSMUST00000006136.4
ENSMUST00000157044.1
ENSMUST00000120009.1
 Dnase1



deoxyribonuclease I



chr13_-_56135629 0.075 ENSMUST00000016081.6
ENSMUST00000045788.7
 H2afy

H2A histone family, member Y

chr9_+_74976096 0.066 ENSMUST00000081746.5
 Fam214a
family with sequence similarity 214, member A
chr19_-_24477356 0.061 ENSMUST00000099556.1
 Fam122a
family with sequence similarity 122, member A
chr11_+_21091291 0.040 ENSMUST00000093290.5
 Peli1
pellino 1
chr11_-_106715251 0.037 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
 Pecam1



platelet/endothelial cell adhesion molecule 1



chr10_+_90829538 0.035 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_134396320 0.035 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2
chr2_-_181599128 0.035 ENSMUST00000060173.8
 Samd10
sterile alpha motif domain containing 10
chrX_+_56786527 0.007 ENSMUST00000144600.1
 Fhl1
four and a half LIM domains 1
chr14_-_68655804 0.004 ENSMUST00000111072.1
ENSMUST00000022642.5
 Adam28

a disintegrin and metallopeptidase domain 28


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 1.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.2 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 1.2 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.1 GO:0070527 platelet aggregation(GO:0070527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0001527 microfibril(GO:0001527)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 2.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0001740 Barr body(GO:0001740)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 0.7 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 1.5 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 5.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)