Motif ID: Sox4

Z-value: 0.275


Transcription factors associated with Sox4:

Gene SymbolEntrez IDGene Name
Sox4 ENSMUSG00000076431.4 Sox4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox4mm10_v2_chr13_-_28953690_28953713-0.281.6e-01Click!


Activity profile for motif Sox4.

activity profile for motif Sox4


Sorted Z-values histogram for motif Sox4

Sorted Z-values for motif Sox4



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox4

PNG image of the network

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Top targets:


Showing 1 to 20 of 108 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 1.523 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr17_-_70851189 0.537 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr7_+_45216671 0.514 ENSMUST00000134420.1
 Tead2
TEA domain family member 2
chr4_+_115057683 0.443 ENSMUST00000161601.1
 Tal1
T cell acute lymphocytic leukemia 1
chrX_+_73639414 0.403 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr3_+_131110350 0.375 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr9_-_103480328 0.353 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr7_+_100493795 0.349 ENSMUST00000129324.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_+_102296256 0.341 ENSMUST00000064924.4
 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr1_+_135729147 0.333 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr12_+_24708984 0.333 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr5_+_75075464 0.321 ENSMUST00000160104.1
ENSMUST00000040477.3
 Gsx2

GS homeobox 2

chr17_-_70853482 0.315 ENSMUST00000118283.1
 Tgif1
TGFB-induced factor homeobox 1
chr12_-_54986363 0.314 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr1_+_153665274 0.314 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr13_+_117220584 0.305 ENSMUST00000022242.7
 Emb
embigin
chr2_-_180776749 0.297 ENSMUST00000061098.2
 Bhlhe23
basic helix-loop-helix family, member e23
chr2_-_180776900 0.295 ENSMUST00000108878.1
 Bhlhe23
basic helix-loop-helix family, member e23
chr11_-_115813621 0.293 ENSMUST00000041684.4
ENSMUST00000156812.1
 Caskin2

CASK-interacting protein 2

chr5_+_115908644 0.285 ENSMUST00000141101.1
 Cit
citron

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.6 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.1 0.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.4 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0 0.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.2 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)