Motif ID: Sox5_Sry

Z-value: 1.449

Transcription factors associated with Sox5_Sry:

Gene SymbolEntrez IDGene Name
Sox5 ENSMUSG00000041540.10 Sox5
Sry ENSMUSG00000069036.3 Sry

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_144209448_1442094690.636.1e-04Click!


Activity profile for motif Sox5_Sry.

activity profile for motif Sox5_Sry


Sorted Z-values histogram for motif Sox5_Sry

Sorted Z-values for motif Sox5_Sry



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox5_Sry

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98329641 3.482 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr4_-_82505274 3.349 ENSMUST00000050872.8
ENSMUST00000064770.2
 Nfib

nuclear factor I/B

chr4_-_82505707 2.963 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr4_-_82505749 2.905 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr3_+_127633134 2.351 ENSMUST00000029587.7
 Neurog2
neurogenin 2
chr2_+_124610573 2.144 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr6_-_144209558 2.044 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr2_-_60125651 2.037 ENSMUST00000112550.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr13_-_56252163 1.921 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr1_+_143640664 1.797 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_+_19103022 1.734 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr4_-_97584612 1.734 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_+_109978004 1.702 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr1_+_6730051 1.648 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr4_-_58499398 1.585 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr4_-_110287479 1.535 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
 Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr4_-_97584605 1.487 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr1_-_45890078 1.412 ENSMUST00000183590.1
 Gm5269
predicted gene 5269
chr6_+_128375456 1.399 ENSMUST00000100926.2
 4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr11_+_94044194 1.288 ENSMUST00000092777.4
ENSMUST00000075695.6
 Spag9

sperm associated antigen 9


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 132 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 10.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 4.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.2 3.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 3.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 2.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 2.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 2.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 2.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.7 2.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 2.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 1.9 GO:0060074 synapse maturation(GO:0060074)
0.2 1.8 GO:0030035 microspike assembly(GO:0030035)
0.2 1.8 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.7 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.4 1.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 10.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 2.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 2.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.1 GO:0030175 filopodium(GO:0030175)
0.0 2.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.3 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.9 GO:0031673 H zone(GO:0031673)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 11.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 7.8 GO:0070888 E-box binding(GO:0070888)
0.1 3.8 GO:0017091 AU-rich element binding(GO:0017091)
0.3 3.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 3.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.1 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 2.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 2.3 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.3 1.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 1.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 1.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.4 GO:0070410 co-SMAD binding(GO:0070410)
0.2 1.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 1.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 1.0 GO:0042895 antibiotic transporter activity(GO:0042895)