Motif ID: Sox8

Z-value: 0.410


Transcription factors associated with Sox8:

Gene SymbolEntrez IDGene Name
Sox8 ENSMUSG00000024176.4 Sox8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox8mm10_v2_chr17_-_25570678_25570694-0.635.5e-04Click!


Activity profile for motif Sox8.

activity profile for motif Sox8


Sorted Z-values histogram for motif Sox8

Sorted Z-values for motif Sox8



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_65512678 1.595 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr3_+_102010138 1.232 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr13_-_66852017 1.041 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr7_-_126800354 0.680 ENSMUST00000106348.1
 Aldoa
aldolase A, fructose-bisphosphate
chr7_-_126800036 0.583 ENSMUST00000133514.1
ENSMUST00000151137.1
 Aldoa

aldolase A, fructose-bisphosphate

chr3_-_8667033 0.569 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_-_46166397 0.476 ENSMUST00000020679.2
 Nipal4
NIPA-like domain containing 4
chr18_-_62741387 0.472 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr10_-_128180265 0.456 ENSMUST00000099139.1
 Rbms2
RNA binding motif, single stranded interacting protein 2
chr11_-_26591729 0.425 ENSMUST00000109504.1
 Vrk2
vaccinia related kinase 2
chr6_-_72380416 0.400 ENSMUST00000101285.3
ENSMUST00000074231.3
 Vamp5

vesicle-associated membrane protein 5

chr6_-_119467210 0.399 ENSMUST00000118120.1
 Wnt5b
wingless-related MMTV integration site 5B
chr19_+_24875679 0.345 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chr13_-_66851513 0.334 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr7_-_42578588 0.332 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr15_-_97020322 0.291 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr13_-_81710937 0.277 ENSMUST00000161920.1
ENSMUST00000048993.5
 Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr16_-_29541483 0.273 ENSMUST00000057018.8
ENSMUST00000182627.1
 Atp13a4

ATPase type 13A4

chr9_-_60838200 0.246 ENSMUST00000063858.7
 Gm9869
predicted gene 9869
chr14_-_49783327 0.219 ENSMUST00000118129.1
ENSMUST00000036972.6
 3632451O06Rik

RIKEN cDNA 3632451O06 gene

chr2_-_181202789 0.212 ENSMUST00000016511.5
 Ptk6
PTK6 protein tyrosine kinase 6
chr8_+_34807287 0.202 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr13_-_19395728 0.192 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr1_+_109993982 0.181 ENSMUST00000027542.6
 Cdh7
cadherin 7, type 2
chr15_-_89149557 0.166 ENSMUST00000088823.3
 Mapk11
mitogen-activated protein kinase 11
chr4_-_58553553 0.165 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
 Lpar1


lysophosphatidic acid receptor 1


chr4_+_11758147 0.164 ENSMUST00000029871.5
ENSMUST00000108303.1
 Cdh17

cadherin 17

chr11_-_43747963 0.162 ENSMUST00000048578.2
ENSMUST00000109278.1
 Ttc1

tetratricopeptide repeat domain 1

chr11_-_69758630 0.159 ENSMUST00000058470.9
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr18_+_80046854 0.153 ENSMUST00000070219.7
 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chrX_+_134404780 0.140 ENSMUST00000113224.2
ENSMUST00000113226.1
 Drp2

dystrophin related protein 2

chr13_-_66227573 0.138 ENSMUST00000167981.2
 Gm10772
predicted gene 10772
chr4_-_129578535 0.134 ENSMUST00000052835.8
 Fam167b
family with sequence similarity 167, member B
chr15_-_99370427 0.090 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
 Fmnl3


formin-like 3


chr17_-_46327949 0.086 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chrX_-_23285532 0.082 ENSMUST00000115319.2
 Klhl13
kelch-like 13
chr4_-_134245579 0.074 ENSMUST00000030644.7
 Zfp593
zinc finger protein 593
chr15_-_103215285 0.070 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chr11_+_32286946 0.069 ENSMUST00000101387.3
 Hbq1b
hemoglobin, theta 1B
chr4_+_154142363 0.069 ENSMUST00000030895.5
 Wrap73
WD repeat containing, antisense to Trp73
chr17_-_46327990 0.068 ENSMUST00000167360.1
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chrX_-_72918284 0.059 ENSMUST00000152200.1
 Cetn2
centrin 2
chr1_+_109983737 0.052 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chr2_-_37647199 0.048 ENSMUST00000028279.3
 Strbp
spermatid perinuclear RNA binding protein
chr13_+_93304799 0.048 ENSMUST00000080127.5
 Homer1
homer homolog 1 (Drosophila)
chr18_-_84951477 0.046 ENSMUST00000025547.2
 Timm21
tranlocase of inner mitochondrial membrane 21
chr2_+_69789647 0.043 ENSMUST00000112266.1
 Phospho2
phosphatase, orphan 2
chr2_-_84715160 0.033 ENSMUST00000035840.5
 Zdhhc5
zinc finger, DHHC domain containing 5
chr3_+_65109343 0.032 ENSMUST00000159525.1
ENSMUST00000049230.8
 Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr11_+_69991061 0.030 ENSMUST00000018711.8
 Gabarap
gamma-aminobutyric acid receptor associated protein
chr9_-_32541589 0.025 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr2_+_69789621 0.023 ENSMUST00000151298.1
ENSMUST00000028494.2
 Phospho2

phosphatase, orphan 2

chr11_+_113659283 0.010 ENSMUST00000137878.1
 Cog1
component of oligomeric golgi complex 1
chr13_+_93304066 0.010 ENSMUST00000109493.1
 Homer1
homer homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 1.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0072610 interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)