Motif ID: Sox8

Z-value: 0.410


Transcription factors associated with Sox8:

Gene SymbolEntrez IDGene Name
Sox8 ENSMUSG00000024176.4 Sox8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox8mm10_v2_chr17_-_25570678_25570694-0.635.5e-04Click!


Activity profile for motif Sox8.

activity profile for motif Sox8


Sorted Z-values histogram for motif Sox8

Sorted Z-values for motif Sox8



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox8

PNG image of the network

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Top targets:


Showing 1 to 20 of 54 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_65512678 1.595 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr3_+_102010138 1.232 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr13_-_66852017 1.041 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr7_-_126800354 0.680 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr7_-_126800036 0.583 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr3_-_8667033 0.569 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_-_46166397 0.476 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr18_-_62741387 0.472 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr10_-_128180265 0.456 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr11_-_26591729 0.425 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr6_-_72380416 0.400 ENSMUST00000101285.3
ENSMUST00000074231.3
Vamp5

vesicle-associated membrane protein 5

chr6_-_119467210 0.399 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr19_+_24875679 0.345 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr13_-_66851513 0.334 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr7_-_42578588 0.332 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr15_-_97020322 0.291 ENSMUST00000166223.1
Slc38a4
solute carrier family 38, member 4
chr13_-_81710937 0.277 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr16_-_29541483 0.273 ENSMUST00000057018.8
ENSMUST00000182627.1
Atp13a4

ATPase type 13A4

chr9_-_60838200 0.246 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr14_-_49783327 0.219 ENSMUST00000118129.1
ENSMUST00000036972.6
3632451O06Rik

RIKEN cDNA 3632451O06 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0072610 interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)