Motif ID: Sp2

Z-value: 0.712


Transcription factors associated with Sp2:

Gene SymbolEntrez IDGene Name
Sp2 ENSMUSG00000018678.6 Sp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp2mm10_v2_chr11_-_96977660_969777110.029.4e-01Click!


Activity profile for motif Sp2.

activity profile for motif Sp2


Sorted Z-values histogram for motif Sp2

Sorted Z-values for motif Sp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 3.941 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_-_17062384 2.014 ENSMUST00000153833.1
ENSMUST00000108492.2
 Hif3a

hypoxia inducible factor 3, alpha subunit

chrX_-_133688978 1.772 ENSMUST00000149154.1
ENSMUST00000167944.1
 Pcdh19

protocadherin 19

chr12_+_112644828 1.615 ENSMUST00000021728.4
ENSMUST00000109755.3
 Siva1

SIVA1, apoptosis-inducing factor

chrX_-_48034842 1.491 ENSMUST00000039026.7
 Apln
apelin
chr6_-_82774448 1.486 ENSMUST00000000642.4
 Hk2
hexokinase 2
chr10_+_128194446 1.325 ENSMUST00000044776.6
 Gls2
glutaminase 2 (liver, mitochondrial)
chr6_+_85187438 1.274 ENSMUST00000045942.8
 Emx1
empty spiracles homeobox 1
chr1_+_184034381 1.253 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10
chr4_-_3938354 1.222 ENSMUST00000003369.3
 Plag1
pleiomorphic adenoma gene 1
chr17_-_70851189 1.199 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr1_+_72824482 1.192 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr6_+_120666388 1.144 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr2_+_38339258 1.110 ENSMUST00000143783.2
 Lhx2
LIM homeobox protein 2
chr4_+_108579445 1.083 ENSMUST00000102744.3
 Orc1
origin recognition complex, subunit 1
chr6_+_107529717 1.072 ENSMUST00000049285.8
 Lrrn1
leucine rich repeat protein 1, neuronal
chr18_+_82914632 1.049 ENSMUST00000071233.6
 Zfp516
zinc finger protein 516
chr6_-_71632897 0.986 ENSMUST00000065509.4
 Kdm3a
lysine (K)-specific demethylase 3A
chr13_-_29984219 0.984 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr2_-_92370999 0.968 ENSMUST00000176810.1
ENSMUST00000090582.4
 Gyltl1b

glycosyltransferase-like 1B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 212 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 2.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.4 2.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 2.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.6 1.9 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 1.8 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.4 1.5 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.3 1.3 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.3 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.3 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.1 1.3 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 1.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.2 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 1.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0016607 nuclear speck(GO:0016607)
0.3 2.1 GO:0000796 condensin complex(GO:0000796)
0.0 2.0 GO:0005903 brush border(GO:0005903)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.1 GO:0090537 CERF complex(GO:0090537)
0.1 1.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.0 1.1 GO:0000922 spindle pole(GO:0000922)
0.1 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 0.9 GO:0031523 Myb complex(GO:0031523)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 0.8 GO:1990423 RZZ complex(GO:1990423)
0.1 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.9 GO:0019841 retinol binding(GO:0019841)
0.0 3.7 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.5 2.6 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.1 2.2 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 1.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.3 GO:0043426 MRF binding(GO:0043426)
0.1 1.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)