Motif ID: Spic
Z-value: 1.422
Transcription factors associated with Spic:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Spic | ENSMUSG00000004359.10 | Spic |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Spic | mm10_v2_chr10_-_88683021_88683025 | 0.20 | 3.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.0 | 11.9 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 1.3 | 6.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.2 | 8.5 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 1.1 | 3.4 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 1.0 | 3.1 | GO:0016068 | regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068) |
| 1.0 | 2.1 | GO:1900673 | olefin metabolic process(GO:1900673) |
| 0.9 | 4.4 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
| 0.9 | 3.5 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.9 | 2.6 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.9 | 2.6 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
| 0.8 | 2.5 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.8 | 2.3 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.7 | 2.2 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) |
| 0.7 | 2.2 | GO:2000561 | CD4-positive, alpha-beta T cell proliferation(GO:0035739) positive regulation of defense response to bacterium(GO:1900426) negative regulation of interferon-gamma secretion(GO:1902714) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.7 | 1.4 | GO:0032701 | negative regulation of interleukin-18 production(GO:0032701) |
| 0.7 | 4.1 | GO:0032796 | uropod organization(GO:0032796) |
| 0.7 | 2.7 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.6 | 1.9 | GO:0045410 | positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
| 0.5 | 7.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.5 | 1.4 | GO:0002606 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) interleukin-3 production(GO:0032632) |
| 0.5 | 3.6 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.4 | 7.5 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.4 | 1.3 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
| 0.4 | 5.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.4 | 3.2 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.3 | 1.3 | GO:0050904 | diapedesis(GO:0050904) |
| 0.3 | 0.9 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.3 | 0.9 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.3 | 0.6 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.3 | 2.1 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.3 | 1.1 | GO:0001907 | killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) |
| 0.3 | 1.6 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.3 | 1.8 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 0.3 | 1.0 | GO:0003430 | tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.3 | 4.0 | GO:0019835 | cytolysis(GO:0019835) |
| 0.2 | 2.0 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.2 | 0.5 | GO:0032700 | negative regulation of interleukin-17 production(GO:0032700) neutrophil mediated killing of bacterium(GO:0070944) |
| 0.2 | 1.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.2 | 0.6 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.2 | 0.5 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.2 | 1.1 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.2 | 1.7 | GO:0090045 | positive regulation of deacetylase activity(GO:0090045) |
| 0.2 | 2.3 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.1 | 0.4 | GO:1902277 | pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) negative regulation of pancreatic amylase secretion(GO:1902277) |
| 0.1 | 2.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.1 | 2.6 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.1 | 0.9 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.1 | 0.4 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.1 | 0.4 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
| 0.1 | 0.9 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 0.7 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.1 | 1.9 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 1.7 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.1 | 1.0 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 1.3 | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
| 0.1 | 0.2 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 0.4 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 5.2 | GO:0047496 | vesicle transport along microtubule(GO:0047496) |
| 0.1 | 0.7 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 1.4 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
| 0.1 | 0.4 | GO:0046469 | platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469) |
| 0.1 | 1.0 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.1 | 0.7 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 2.2 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.1 | 0.4 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
| 0.1 | 1.2 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 0.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.1 | 0.9 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.1 | 0.2 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.1 | 0.5 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.1 | 0.6 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.1 | 0.2 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
| 0.1 | 1.1 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 0.2 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.1 | 1.9 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.9 | GO:0015816 | glycine transport(GO:0015816) |
| 0.1 | 1.0 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 2.1 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 0.3 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) |
| 0.1 | 0.7 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
| 0.1 | 1.0 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.5 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.1 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 0.7 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.1 | 0.2 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.1 | 0.6 | GO:0097576 | autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576) |
| 0.1 | 0.5 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.1 | 0.8 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.8 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 0.5 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.5 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 0.6 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
| 0.0 | 0.2 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.0 | 1.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.0 | 0.8 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.2 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.0 | 0.4 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.0 | 0.2 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.0 | 0.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.0 | 1.9 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.0 | 0.2 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
| 0.0 | 0.5 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.0 | 0.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 1.4 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 2.1 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
| 0.0 | 0.8 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.0 | 0.7 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.0 | 0.2 | GO:0035405 | regulation of germinal center formation(GO:0002634) histone-threonine phosphorylation(GO:0035405) |
| 0.0 | 0.1 | GO:1904683 | regulation of metalloendopeptidase activity(GO:1904683) negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049) |
| 0.0 | 0.1 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.0 | 0.6 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 0.1 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.8 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.0 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.0 | 0.1 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.0 | 0.7 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.0 | 0.3 | GO:0045954 | positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
| 0.0 | 1.6 | GO:0035904 | aorta development(GO:0035904) |
| 0.0 | 0.6 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.4 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.5 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.3 | GO:0017144 | drug metabolic process(GO:0017144) |
| 0.0 | 0.1 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.0 | 1.1 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.0 | 0.2 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.0 | 0.2 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.0 | 0.5 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
| 0.0 | 0.4 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.4 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.8 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.0 | 0.7 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 2.5 | GO:0008643 | carbohydrate transport(GO:0008643) |
| 0.0 | 0.6 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
| 0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.4 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.0 | 0.4 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 1.8 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.7 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.1 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.0 | 0.5 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.0 | 1.4 | GO:0007219 | Notch signaling pathway(GO:0007219) |
| 0.0 | 0.7 | GO:0019233 | sensory perception of pain(GO:0019233) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.0 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.7 | 2.2 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.7 | 3.4 | GO:1990745 | EARP complex(GO:1990745) |
| 0.5 | 3.6 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.5 | 2.1 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.4 | 1.8 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.4 | 2.6 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.3 | 1.4 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.3 | 1.3 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.3 | 1.0 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.2 | 16.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.2 | 2.1 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.2 | 0.6 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.2 | 1.0 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.2 | 0.6 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.2 | 0.9 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.2 | 0.5 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.2 | 2.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 5.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.2 | 0.5 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.2 | 0.7 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.2 | 2.0 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.2 | 0.8 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.2 | 4.1 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 1.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.2 | 2.0 | GO:0042581 | specific granule(GO:0042581) |
| 0.1 | 4.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 0.4 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 1.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 3.1 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 1.7 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 0.8 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.8 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 1.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 16.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 2.3 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 0.3 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.1 | 4.3 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.4 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 0.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.1 | 0.4 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 11.3 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.1 | 0.6 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 1.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.3 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 0.5 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 9.2 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.6 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.6 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 4.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 1.2 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.8 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.5 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.2 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.0 | 0.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.4 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.0 | 1.2 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 1.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 1.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.6 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 2.7 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 3.1 | GO:0005768 | endosome(GO:0005768) |
| 0.0 | 1.4 | GO:0072372 | primary cilium(GO:0072372) |
| 0.0 | 0.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.1 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 15.0 | GO:0019864 | IgG binding(GO:0019864) |
| 1.2 | 5.8 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.9 | 6.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.9 | 3.5 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.9 | 2.6 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
| 0.6 | 2.5 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.6 | 4.6 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.6 | 3.9 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.5 | 2.3 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.4 | 4.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.4 | 2.2 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.3 | 3.8 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.3 | 2.0 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.3 | 2.0 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.3 | 1.3 | GO:0071253 | connexin binding(GO:0071253) |
| 0.3 | 1.0 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.2 | 1.2 | GO:0018121 | imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102) |
| 0.2 | 0.7 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
| 0.2 | 2.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.2 | 4.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.2 | 1.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 2.6 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.2 | 0.6 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.2 | 4.8 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.2 | 0.5 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.2 | 1.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.2 | 0.5 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.2 | 0.2 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 0.4 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 2.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 4.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 0.4 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 1.4 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.1 | 1.0 | GO:0052872 | 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014) |
| 0.1 | 0.6 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.1 | 1.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 1.6 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 0.9 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.1 | 1.0 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
| 0.1 | 1.1 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.1 | 0.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 2.2 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.2 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.1 | 1.7 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.1 | 0.3 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 0.9 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.3 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 0.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.1 | 0.6 | GO:0001846 | opsonin binding(GO:0001846) |
| 0.1 | 0.2 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.1 | 0.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 1.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 5.4 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 1.2 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 0.5 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 0.7 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 0.6 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 1.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.2 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.0 | 0.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.2 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
| 0.0 | 0.2 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.0 | 0.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.1 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) |
| 0.0 | 1.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.2 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.0 | 0.7 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.0 | 1.2 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 1.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 1.0 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 0.5 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 0.2 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.5 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.0 | 0.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 2.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 4.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.7 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.0 | 1.2 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.0 | 0.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.6 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.6 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 1.3 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.0 | 0.2 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.0 | 2.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.8 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.5 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 1.6 | GO:0019209 | kinase activator activity(GO:0019209) |
| 0.0 | 0.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.4 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.3 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 1.5 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.0 | 0.1 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.0 | 0.8 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 0.6 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.6 | GO:0005179 | hormone activity(GO:0005179) |
