Motif ID: Stat1

Z-value: 0.911


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_52119499-0.618.9e-04Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Showing 1 to 20 of 154 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 5.714 ENSMUST00000107377.3
 Tnc
tenascin C
chr11_+_78499087 4.334 ENSMUST00000017488.4
 Vtn
vitronectin
chr6_+_115134899 3.985 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chr3_-_80802789 3.307 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr7_+_45783883 3.146 ENSMUST00000072580.5
 Lmtk3
lemur tyrosine kinase 3
chr7_+_45783686 3.083 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chr4_+_43401232 2.770 ENSMUST00000125399.1
 Rusc2
RUN and SH3 domain containing 2
chr15_-_93519499 2.598 ENSMUST00000109255.2
 Prickle1
prickle homolog 1 (Drosophila)
chrX_-_61185558 2.547 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr9_+_107296843 2.500 ENSMUST00000167072.1
 Cish
cytokine inducible SH2-containing protein
chr2_+_178193075 2.476 ENSMUST00000103065.1
 Phactr3
phosphatase and actin regulator 3
chr19_-_46327121 2.406 ENSMUST00000041391.4
ENSMUST00000096029.5
 Psd

pleckstrin and Sec7 domain containing

chr8_-_70776650 2.395 ENSMUST00000034296.8
 Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr18_-_33463615 2.394 ENSMUST00000051087.8
 Nrep
neuronal regeneration related protein
chr16_-_42340595 2.359 ENSMUST00000102817.4
 Gap43
growth associated protein 43
chr9_+_107296682 2.319 ENSMUST00000168260.1
 Cish
cytokine inducible SH2-containing protein
chr11_+_82035569 2.135 ENSMUST00000000193.5
 Ccl2
chemokine (C-C motif) ligand 2
chr12_+_74297474 2.131 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr4_-_136886187 2.130 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr8_+_70673364 2.123 ENSMUST00000146972.1
 Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 6.1 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
1.4 5.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.5 5.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 4.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 4.3 GO:0097421 liver regeneration(GO:0097421)
0.1 3.6 GO:0034340 response to type I interferon(GO:0034340)
0.2 3.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.5 3.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 3.0 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 2.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.9 2.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.4 2.4 GO:0016198 axon choice point recognition(GO:0016198)
0.1 2.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 2.4 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 2.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.5 2.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 5.7 GO:0005614 interstitial matrix(GO:0005614)
0.9 4.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 4.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 3.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 3.0 GO:0005581 collagen trimer(GO:0005581)
0.2 2.4 GO:0005688 U6 snRNP(GO:0005688)
0.1 2.2 GO:0031527 filopodium membrane(GO:0031527)
0.7 2.1 GO:0044299 C-fiber(GO:0044299)
0.0 2.1 GO:0055037 recycling endosome(GO:0055037)
0.3 2.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.3 1.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 1.2 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.7 GO:0045545 syndecan binding(GO:0045545)
0.2 5.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 4.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.9 3.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 3.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.6 3.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 3.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 3.0 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.5 2.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 2.5 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.4 2.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 2.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 2.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.4 GO:0002020 protease binding(GO:0002020)
0.6 2.2 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) interleukin-20 binding(GO:0042015)
0.1 2.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 2.0 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 2.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.9 GO:0043531 ADP binding(GO:0043531)