Motif ID: Stat4_Stat3_Stat5b

Z-value: 0.917

Transcription factors associated with Stat4_Stat3_Stat5b:

Gene SymbolEntrez IDGene Name
Stat3 ENSMUSG00000004040.10 Stat3
Stat4 ENSMUSG00000062939.5 Stat4
Stat5b ENSMUSG00000020919.5 Stat5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat4mm10_v2_chr1_+_51987139_51987151-0.491.1e-02Click!
Stat5bmm10_v2_chr11_-_100822525_100822576-0.385.8e-02Click!
Stat3mm10_v2_chr11_-_100939357_1009394560.311.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Stat4_Stat3_Stat5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_64046925 7.886 ENSMUST00000107377.3
Tnc
tenascin C
chrX_-_61185558 6.063 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr3_-_80802789 5.682 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr9_+_107296843 4.520 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr16_-_23988852 3.402 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr16_-_74411292 2.536 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411776 2.535 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr6_+_115134899 2.479 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr10_-_95417099 2.118 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr12_+_74297474 1.922 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr7_+_107567445 1.812 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr9_+_107296682 1.710 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr17_+_26715644 1.701 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr3_-_88000350 1.633 ENSMUST00000090971.5
Bcan
brevican
chr4_+_11704439 1.623 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr10_+_13966268 1.599 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_78577771 1.552 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr10_-_95416850 1.540 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr16_-_67620880 1.417 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr12_+_11265867 1.413 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr12_+_82616885 1.321 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr5_+_88886809 1.295 ENSMUST00000148750.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr6_-_5496296 1.272 ENSMUST00000019721.4
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr4_-_108031938 1.240 ENSMUST00000106708.1
Podn
podocan
chr11_+_78324200 1.233 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr16_-_67620805 1.225 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr1_+_134182404 1.212 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr19_-_46327121 1.202 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr4_-_108032069 1.171 ENSMUST00000106709.2
Podn
podocan
chr3_+_122245557 1.168 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit
chr5_+_14025305 1.166 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_-_126202335 1.136 ENSMUST00000142125.1
ENSMUST00000106141.2
Thrap3

thyroid hormone receptor associated protein 3

chr10_-_54075730 1.129 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr4_+_148602527 1.113 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr11_-_117969176 1.085 ENSMUST00000054002.3
Socs3
suppressor of cytokine signaling 3
chr13_-_67755132 1.062 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr1_+_34005872 1.032 ENSMUST00000182296.1
Dst
dystonin
chr17_+_39846958 0.981 ENSMUST00000182010.1
Gm26924
predicted gene, 26924
chr15_-_93519499 0.959 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr13_-_67755192 0.908 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr7_+_24112314 0.881 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr11_-_101785252 0.878 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr19_-_21652714 0.877 ENSMUST00000177577.1
1110059E24Rik
RIKEN cDNA 1110059E24 gene
chr7_+_24507099 0.876 ENSMUST00000177228.1
Zfp428
zinc finger protein 428
chr18_+_65873478 0.871 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr3_+_96576984 0.867 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr3_-_51560816 0.862 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr7_+_24134148 0.849 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr14_+_65970610 0.842 ENSMUST00000127387.1
Clu
clusterin
chr14_+_65971049 0.834 ENSMUST00000128539.1
Clu
clusterin
chr2_-_104257400 0.824 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr2_+_3424123 0.810 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr10_+_40349265 0.806 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr11_-_107915041 0.803 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr7_+_28180272 0.795 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr14_+_65970804 0.784 ENSMUST00000138191.1
Clu
clusterin
chr2_+_178193075 0.775 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr15_-_37458523 0.771 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr11_-_77787747 0.765 ENSMUST00000092883.2
Gm10277
predicted gene 10277
chr19_-_5797410 0.760 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr2_-_120970706 0.751 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr3_+_33799791 0.749 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr1_+_136624901 0.736 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr5_+_123015010 0.729 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr14_+_65971164 0.725 ENSMUST00000144619.1
Clu
clusterin
chr10_+_69925766 0.711 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr10_-_54075702 0.705 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr15_-_75566608 0.700 ENSMUST00000163116.1
ENSMUST00000023241.5
Ly6h

lymphocyte antigen 6 complex, locus H

chrX_+_82948861 0.696 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr15_+_99224976 0.694 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr19_+_34550664 0.686 ENSMUST00000149829.1
ENSMUST00000102826.3
Ifit2

interferon-induced protein with tetratricopeptide repeats 2

chr19_+_38481057 0.685 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr16_+_91372783 0.683 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr12_+_85473883 0.677 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chrX_-_53608979 0.676 ENSMUST00000123034.1
Gm14597
predicted gene 14597
chr1_+_134182150 0.671 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr6_+_135198034 0.667 ENSMUST00000130612.1
8430419L09Rik
RIKEN cDNA 8430419L09 gene
chr9_+_20868628 0.665 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr9_-_112232449 0.660 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr5_+_98180866 0.657 ENSMUST00000112959.1
Prdm8
PR domain containing 8
chr4_-_15149051 0.646 ENSMUST00000041606.7
Necab1
N-terminal EF-hand calcium binding protein 1
chr3_+_94693556 0.640 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr11_+_3488275 0.638 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr5_-_142817387 0.638 ENSMUST00000036253.6
Tnrc18
trinucleotide repeat containing 18
chr6_+_108660772 0.636 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr8_-_70776650 0.636 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr17_+_34145231 0.629 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr15_-_37459327 0.627 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr6_+_135197977 0.627 ENSMUST00000111915.1
ENSMUST00000111916.1
8430419L09Rik

RIKEN cDNA 8430419L09 gene

chr5_+_130448801 0.626 ENSMUST00000111288.2
Caln1
calneuron 1
chr19_+_34217588 0.625 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chr4_+_49521176 0.622 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr2_+_130405256 0.618 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr18_-_23041641 0.613 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr15_-_75566811 0.608 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr11_+_53519920 0.590 ENSMUST00000147912.1
Sept8
septin 8
chr18_+_23415400 0.588 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr19_-_29047847 0.586 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr3_-_85741389 0.585 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr12_+_16653470 0.584 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr1_+_17145357 0.580 ENSMUST00000026879.7
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr2_-_33371400 0.576 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr2_-_33371486 0.576 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr10_+_20312461 0.571 ENSMUST00000092678.3
ENSMUST00000043881.5
Bclaf1

BCL2-associated transcription factor 1

chr10_+_29143996 0.561 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr15_-_75567176 0.558 ENSMUST00000156032.1
ENSMUST00000127095.1
Ly6h

lymphocyte antigen 6 complex, locus H

chr11_-_69695802 0.554 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr11_-_48871344 0.553 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr11_+_53519725 0.549 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr3_-_10440054 0.544 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr11_+_53519871 0.544 ENSMUST00000120878.2
Sept8
septin 8
chr11_+_82035569 0.541 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr7_-_128461630 0.532 ENSMUST00000106226.2
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr10_+_69925954 0.525 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr16_+_91372865 0.523 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr1_+_152399824 0.520 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr18_+_90510122 0.519 ENSMUST00000025515.6
Tmx3
thioredoxin-related transmembrane protein 3
chr7_+_28180226 0.518 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_-_128461168 0.517 ENSMUST00000106228.1
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr17_-_43667015 0.514 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr12_-_64965496 0.514 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr12_+_88953399 0.514 ENSMUST00000057634.7
Nrxn3
neurexin III
chr7_+_29768552 0.513 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr7_+_30095150 0.513 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr3_-_69004503 0.511 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr16_-_20426322 0.508 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr3_-_107760221 0.506 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr5_-_147076482 0.505 ENSMUST00000016664.7
Lnx2
ligand of numb-protein X 2
chr4_+_136310991 0.505 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr2_-_168712853 0.504 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr4_+_49059256 0.496 ENSMUST00000076670.2
E130309F12Rik
RIKEN cDNA E130309F12 gene
chr16_+_91647859 0.492 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son



Son DNA binding protein



chr7_+_82335732 0.490 ENSMUST00000173287.1
Adamtsl3
ADAMTS-like 3
chr10_+_69925800 0.489 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr9_+_21015960 0.488 ENSMUST00000086399.4
Icam1
intercellular adhesion molecule 1
chr8_+_25532125 0.486 ENSMUST00000167764.1
Fgfr1
fibroblast growth factor receptor 1
chr12_-_4477138 0.485 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr5_-_9725305 0.483 ENSMUST00000004076.3
Grm3
glutamate receptor, metabotropic 3
chr3_+_122245625 0.478 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr2_-_132578155 0.477 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr2_-_132578244 0.473 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr6_+_86438360 0.468 ENSMUST00000050497.7
C87436
expressed sequence C87436
chr10_-_89732253 0.468 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr4_-_140617062 0.460 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_+_32238713 0.458 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr4_-_136886187 0.457 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr8_+_70673364 0.448 ENSMUST00000146972.1
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_-_54919961 0.442 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr12_-_41485751 0.438 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr11_+_77765588 0.432 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr7_+_28179469 0.429 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr5_-_86172747 0.428 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr9_+_59750876 0.427 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr1_-_130729249 0.426 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr11_+_49203285 0.422 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr2_-_37422869 0.418 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr4_+_136310952 0.418 ENSMUST00000105850.1
ENSMUST00000148843.3
Hnrnpr

heterogeneous nuclear ribonucleoprotein R

chr1_+_176814660 0.417 ENSMUST00000056773.8
ENSMUST00000027785.8
Sdccag8

serologically defined colon cancer antigen 8

chr3_-_69004565 0.416 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr1_-_155812859 0.415 ENSMUST00000035325.8
Qsox1
quiescin Q6 sulfhydryl oxidase 1
chr2_-_38287347 0.415 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr10_-_127041513 0.413 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr14_-_55106547 0.410 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr4_+_42917234 0.410 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chrX_-_160994665 0.409 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr17_+_45433823 0.409 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr2_-_77519565 0.408 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr13_-_110280103 0.406 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr3_+_63295815 0.404 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chrX_-_95026671 0.404 ENSMUST00000096367.3
Spin4
spindlin family, member 4
chr16_-_20426375 0.403 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr13_+_14063776 0.402 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr11_+_17051818 0.401 ENSMUST00000058159.5
Cnrip1
cannabinoid receptor interacting protein 1
chr5_-_34513892 0.394 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr1_-_155812805 0.393 ENSMUST00000111764.2
Qsox1
quiescin Q6 sulfhydryl oxidase 1
chr9_-_101198999 0.391 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr14_+_27622433 0.390 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr11_+_49203465 0.390 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr7_+_113514085 0.389 ENSMUST00000122890.1
Far1
fatty acyl CoA reductase 1
chr2_-_38287174 0.388 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr2_+_23068168 0.387 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chr1_+_104768510 0.383 ENSMUST00000062528.8
Cdh20
cadherin 20
chr13_-_77135416 0.380 ENSMUST00000159462.1
ENSMUST00000151524.2
Ankrd32

ankyrin repeat domain 32

chr7_-_105399991 0.380 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr12_-_11265768 0.376 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr6_-_24515036 0.375 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr18_+_37020097 0.371 ENSMUST00000047614.1
Pcdha2
protocadherin alpha 2
chr13_+_109903089 0.371 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr3_-_127780461 0.370 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr5_-_150665315 0.369 ENSMUST00000141857.1
N4bp2l2
NEDD4 binding protein 2-like 2
chr3_-_69004475 0.368 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr7_+_24270420 0.367 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr16_+_38089001 0.366 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr7_+_25268387 0.364 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr17_-_51826562 0.363 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr17_+_34145311 0.363 ENSMUST00000041982.7
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr13_+_77135513 0.363 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr13_+_67128219 0.360 ENSMUST00000052716.7
Zfp759
zinc finger protein 759
chr1_-_136260873 0.359 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr1_-_155146755 0.359 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.7 5.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.1 3.4 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.5 3.2 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.5 1.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.4 1.8 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.4 0.4 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.4 1.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 1.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 1.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.3 0.8 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.2 6.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 5.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.2 0.8 GO:0035063 nuclear speck organization(GO:0035063)
0.2 0.4 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 1.6 GO:0051409 response to nitrosative stress(GO:0051409)
0.2 2.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.5 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 3.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 0.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 0.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.5 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.2 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 1.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.5 GO:2000569 T-helper 2 cell activation(GO:0035712) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.9 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.9 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.4 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.3 GO:0042505 tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.5 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) regulation of response to drug(GO:2001023)
0.1 0.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 1.9 GO:0034340 response to type I interferon(GO:0034340)
0.1 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.3 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) necroptotic signaling pathway(GO:0097527)
0.1 1.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.3 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.1 1.3 GO:0061157 mRNA destabilization(GO:0061157)
0.1 2.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.2 GO:0070269 pyroptosis(GO:0070269)
0.1 0.2 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.2 GO:0033136 serine phosphorylation of STAT3 protein(GO:0033136)
0.1 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.7 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.1 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 0.2 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 0.3 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.7 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 1.2 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.0 GO:0071335 hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.3 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.4 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 1.3 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 1.6 GO:0021766 hippocampus development(GO:0021766)
0.0 0.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.5 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.0 0.2 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.4 GO:0007099 centriole replication(GO:0007099)
0.0 1.7 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0045072 enucleate erythrocyte differentiation(GO:0043353) regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.6 GO:0043620 regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.0 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 2.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.5 GO:0017145 stem cell division(GO:0017145)
0.0 0.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.0 GO:0090285 regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.5 8.0 GO:0005614 interstitial matrix(GO:0005614)
0.5 1.4 GO:0035061 interchromatin granule(GO:0035061)
0.5 3.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.3 5.7 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.0 GO:0031673 H zone(GO:0031673)
0.2 0.5 GO:0044299 C-fiber(GO:0044299)
0.2 5.1 GO:0030673 axolemma(GO:0030673)
0.2 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.3 GO:0090537 CERF complex(GO:0090537)
0.1 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.8 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 2.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0033263 HOPS complex(GO:0030897) CORVET complex(GO:0033263)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 2.2 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0097342 death-inducing signaling complex(GO:0031264) ripoptosome(GO:0097342)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 1.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.9 GO:0045545 syndecan binding(GO:0045545)
0.9 5.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.8 3.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.6 5.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 1.6 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.4 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 1.2 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) interleukin-20 binding(GO:0042015)
0.3 1.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.2 2.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 1.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 1.8 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 1.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 3.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.8 GO:0070728 leucine binding(GO:0070728)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 0.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0097001 sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001)
0.1 1.0 GO:0001846 opsonin binding(GO:0001846)
0.1 0.3 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.4 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.1 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.6 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 6.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.0 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.1 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.7 GO:0017166 dystroglycan binding(GO:0002162) vinculin binding(GO:0017166)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0032052 purine nucleobase binding(GO:0002060) bile acid binding(GO:0032052)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 0.3 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)