Motif ID: Stat5a

Z-value: 1.026


Transcription factors associated with Stat5a:

Gene SymbolEntrez IDGene Name
Stat5a ENSMUSG00000004043.8 Stat5a



Activity profile for motif Stat5a.

activity profile for motif Stat5a


Sorted Z-values histogram for motif Stat5a

Sorted Z-values for motif Stat5a



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat5a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_42583628 3.580 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr9_-_79977782 3.495 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr6_+_4755327 3.472 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr7_-_103853199 2.900 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr10_+_22158566 2.517 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr9_+_92250039 2.440 ENSMUST00000093801.3
 Plscr1
phospholipid scramblase 1
chr6_+_65381294 2.376 ENSMUST00000170608.1
 C130060K24Rik
RIKEN cDNA C130060K24 gene
chr7_-_144939823 2.329 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr1_+_96872221 2.264 ENSMUST00000181489.1
 Gm5101
predicted gene 5101
chr10_+_84838143 2.258 ENSMUST00000095388.4
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr3_-_25212720 2.218 ENSMUST00000091289.3
 Gm10259
predicted pseudogene 10259
chr15_-_94404258 2.202 ENSMUST00000035342.4
ENSMUST00000155907.1
 Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chr14_-_48665098 2.196 ENSMUST00000118578.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr7_+_88278085 2.182 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr12_+_109734969 2.097 ENSMUST00000182268.1
ENSMUST00000181543.2
ENSMUST00000183116.1
 Mirg


miRNA containing gene


chr2_-_168767136 2.088 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr2_-_117342709 1.997 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
 Rasgrp1


RAS guanyl releasing protein 1


chr2_-_180824596 1.973 ENSMUST00000148700.1
 Gm14340
predicted gene 14340
chr9_-_114564315 1.963 ENSMUST00000111816.2
 Trim71
tripartite motif-containing 71
chr17_-_25797032 1.940 ENSMUST00000165838.1
ENSMUST00000002344.6
 Metrn

meteorin, glial cell differentiation regulator


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 438 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.8 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.6 5.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.0 4.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 3.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.4 3.5 GO:0090399 replicative senescence(GO:0090399)
0.7 3.3 GO:0021764 amygdala development(GO:0021764)
0.2 3.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 3.0 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.2 3.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.6 2.9 GO:0015671 oxygen transport(GO:0015671)
0.3 2.9 GO:0002176 male germ cell proliferation(GO:0002176)
0.2 2.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 2.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 2.7 GO:0006273 lagging strand elongation(GO:0006273)
0.6 2.5 GO:0046061 dATP catabolic process(GO:0046061)
0.8 2.4 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3 2.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.5 2.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.4 2.2 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 2.2 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 178 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 4.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 3.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.0 3.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 2.9 GO:0005833 hemoglobin complex(GO:0005833)
0.2 2.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.8 2.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 2.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.3 GO:0000922 spindle pole(GO:0000922)
0.2 2.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 2.2 GO:0001741 XY body(GO:0001741)
0.1 2.2 GO:0032420 stereocilium(GO:0032420)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.3 2.1 GO:0005818 aster(GO:0005818)
0.3 2.0 GO:0000796 condensin complex(GO:0000796)
0.2 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.9 GO:0070938 contractile ring(GO:0070938)
0.3 1.8 GO:0042627 chylomicron(GO:0042627)
0.1 1.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 273 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 3.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 3.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 3.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 3.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.7 2.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 2.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 2.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.3 2.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 2.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 2.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 2.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.3 GO:0004601 peroxidase activity(GO:0004601)
0.5 2.2 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 2.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.4 2.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 2.0 GO:0001784 phosphotyrosine binding(GO:0001784)