Motif ID: Stat6
Z-value: 0.860
Transcription factors associated with Stat6:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Stat6 | ENSMUSG00000002147.12 | Stat6 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Stat6 | mm10_v2_chr10_+_127642975_127643034 | 0.36 | 7.3e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
1.2 | 3.5 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.8 | 5.1 | GO:0098700 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.6 | 2.8 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.5 | 3.8 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.3 | 0.9 | GO:0086017 | renin secretion into blood stream(GO:0002001) cell communication by chemical coupling(GO:0010643) Purkinje myocyte action potential(GO:0086017) regulation of renin secretion into blood stream(GO:1900133) |
0.3 | 2.0 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
0.2 | 0.6 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.2 | 0.5 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.2 | 0.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.2 | 0.8 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
0.2 | 1.6 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.2 | 0.6 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.2 | 3.9 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 0.4 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
0.1 | 0.4 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.1 | 0.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
0.1 | 0.8 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
0.1 | 1.3 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.1 | 0.8 | GO:0071493 | cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399) |
0.1 | 2.3 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.1 | 0.4 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 1.9 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
0.1 | 2.8 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.1 | 1.1 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.1 | 0.2 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
0.1 | 0.4 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.1 | 0.4 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
0.1 | 0.1 | GO:1904173 | regulation of histone demethylase activity (H3-K4 specific)(GO:1904173) |
0.1 | 1.9 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.1 | 0.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.1 | 3.1 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.1 | 0.2 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
0.0 | 1.8 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
0.0 | 1.7 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 0.2 | GO:0070295 | renal water absorption(GO:0070295) |
0.0 | 0.2 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
0.0 | 0.2 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
0.0 | 0.2 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.0 | 0.7 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
0.0 | 0.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 1.8 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
0.0 | 0.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
0.0 | 1.1 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.0 | 0.7 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.4 | GO:0019835 | cytolysis(GO:0019835) |
0.0 | 0.7 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.2 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 1.1 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.0 | 0.8 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.1 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
0.0 | 0.1 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.0 | 0.0 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
0.0 | 0.7 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.3 | 0.8 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.2 | 0.9 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.1 | 1.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.9 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 0.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.0 | 2.0 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.0 | 0.5 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
0.0 | 0.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 0.4 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.0 | 0.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 1.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.1 | GO:0030891 | VCB complex(GO:0030891) |
0.0 | 0.1 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.2 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.1 | GO:0044613 | nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543) |
0.0 | 0.1 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.0 | 0.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.7 | GO:0016459 | myosin complex(GO:0016459) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.1 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.3 | 2.8 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.3 | 2.0 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.3 | 1.6 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.3 | 1.8 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.2 | 1.8 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.2 | 0.6 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.2 | 0.9 | GO:0071253 | connexin binding(GO:0071253) |
0.1 | 0.8 | GO:0043426 | MRF binding(GO:0043426) |
0.1 | 1.0 | GO:0042301 | phosphate ion binding(GO:0042301) |
0.1 | 0.2 | GO:0048045 | 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623) |
0.1 | 3.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.1 | 0.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 0.4 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 0.2 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.1 | 1.1 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 0.8 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.8 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.0 | 1.8 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 2.4 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.2 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
0.0 | 0.5 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 1.3 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 1.2 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 1.5 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.7 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 0.2 | GO:0015288 | porin activity(GO:0015288) |
0.0 | 0.1 | GO:0051425 | PTB domain binding(GO:0051425) |
0.0 | 0.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.0 | 0.1 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
0.0 | 0.1 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 1.5 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.1 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 0.8 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.0 | 0.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.0 | 0.5 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 3.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |