Motif ID: Tbp

Z-value: 1.713


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.395.2e-02Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 6.372 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr3_+_87948666 4.779 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr11_+_94936224 3.945 ENSMUST00000001547.7
 Col1a1
collagen, type I, alpha 1
chr7_-_103843154 2.915 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr7_-_103813913 2.893 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr13_+_21717626 2.647 ENSMUST00000091754.2
 Hist1h3h
histone cluster 1, H3h
chr2_-_164857542 2.642 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr17_+_24720063 2.450 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
 Rps2


ribosomal protein S2


chr1_-_138842429 2.088 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr1_-_171196229 1.908 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr7_-_103827922 1.900 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr6_-_136875794 1.692 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr1_+_109993982 1.615 ENSMUST00000027542.6
 Cdh7
cadherin 7, type 2
chr13_-_21780616 1.597 ENSMUST00000080511.2
 Hist1h1b
histone cluster 1, H1b
chr17_-_33824346 1.579 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
 Rps28




ribosomal protein S28




chr3_-_145649970 1.482 ENSMUST00000029846.3
 Cyr61
cysteine rich protein 61
chr13_-_21750505 1.464 ENSMUST00000102983.1
 Hist1h4k
histone cluster 1, H4k
chr13_-_23745511 1.443 ENSMUST00000091752.2
 Hist1h3c
histone cluster 1, H3c
chr12_+_3954943 1.433 ENSMUST00000020990.5
 Pomc
pro-opiomelanocortin-alpha
chr4_-_132353605 1.412 ENSMUST00000155129.1
 Rcc1
regulator of chromosome condensation 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 11.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.9 9.3 GO:0015671 oxygen transport(GO:0015671)
0.1 6.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 5.0 GO:0006342 chromatin silencing(GO:0006342)
0.4 4.8 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.6 3.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 3.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 3.1 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.2 2.9 GO:0019430 removal of superoxide radicals(GO:0019430)
0.7 2.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.7 2.6 GO:0042360 vitamin E metabolic process(GO:0042360)
0.4 2.6 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.2 2.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 2.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 2.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 1.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 1.8 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 1.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 1.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.5 1.5 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 14.1 GO:0005833 hemoglobin complex(GO:0005833)
0.3 12.4 GO:0000786 nucleosome(GO:0000786)
0.4 12.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 8.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.3 GO:0043209 myelin sheath(GO:0043209)
1.3 3.9 GO:0005584 collagen type I trimer(GO:0005584)
0.1 3.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 3.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 2.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 2.3 GO:0097452 GAIT complex(GO:0097452)
0.0 2.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.1 GO:0000776 kinetochore(GO:0000776)
0.3 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.1 1.5 GO:0005921 gap junction(GO:0005921)
0.0 1.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 1.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.3 GO:0042393 histone binding(GO:0042393)
3.5 14.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 8.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 5.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.8 4.8 GO:0019841 retinol binding(GO:0019841)
0.3 3.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.6 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 2.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.8 2.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 1.9 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 1.4 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.5 1.4 GO:0001847 opsonin receptor activity(GO:0001847) anaphylatoxin receptor activity(GO:0004942)
0.2 1.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)