Motif ID: Tbx15

Z-value: 0.466


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_48045144 2.253 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr4_-_129121889 1.654 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr6_+_115134899 1.127 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr16_-_23988852 1.097 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr14_-_55116935 1.058 ENSMUST00000022819.5
Jph4
junctophilin 4
chr12_-_78980758 0.993 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr3_+_96181151 0.992 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr4_-_82505749 0.988 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr7_+_130936172 0.980 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr5_+_32136458 0.967 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chrX_+_7919816 0.947 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr19_-_10304867 0.934 ENSMUST00000039327.4
Dagla
diacylglycerol lipase, alpha
chr4_+_125490688 0.924 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr17_-_81649607 0.881 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr11_-_116654245 0.862 ENSMUST00000021166.5
Cygb
cytoglobin
chr11_+_98348404 0.835 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr10_+_123264076 0.832 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chrX_+_159840463 0.749 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr6_+_108213086 0.729 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr3_+_75557530 0.726 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 2.3 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.7 2.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 1.4 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 1.2 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.5 1.1 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.4 1.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 1.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.3 1.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 0.9 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 0.9 GO:0015671 oxygen transport(GO:0015671)
0.1 0.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.9 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3 0.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.2 0.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.5 GO:0030275 LRR domain binding(GO:0030275)
0.2 1.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 1.1 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 0.9 GO:0004096 catalase activity(GO:0004096)
0.2 0.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.3 0.8 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)