Motif ID: Tbx1_Eomes
Z-value: 0.781
Transcription factors associated with Tbx1_Eomes:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Eomes | ENSMUSG00000032446.8 | Eomes |
Tbx1 | ENSMUSG00000009097.9 | Tbx1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Eomes | mm10_v2_chr9_+_118478344_118478451 | 0.17 | 4.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 4.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
0.7 | 2.0 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.5 | 2.7 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.5 | 1.5 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
0.5 | 2.5 | GO:0030091 | protein repair(GO:0030091) |
0.5 | 0.9 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
0.4 | 1.5 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.4 | 4.6 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
0.3 | 1.0 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
0.3 | 2.5 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.3 | 0.9 | GO:0090526 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.3 | 0.9 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.3 | 0.8 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
0.3 | 3.1 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.2 | 0.7 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.2 | 2.2 | GO:0071493 | cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399) |
0.2 | 0.9 | GO:0007412 | axon target recognition(GO:0007412) |
0.2 | 2.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.2 | 0.5 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.2 | 0.7 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.2 | 2.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.2 | 0.6 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.2 | 0.6 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.2 | 1.5 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
0.1 | 0.4 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.1 | 1.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 2.4 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.1 | 0.9 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 1.1 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 2.9 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.1 | 0.3 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.1 | 1.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.4 | GO:1903587 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
0.1 | 0.7 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.1 | 0.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.9 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.1 | 0.5 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.1 | 0.9 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.1 | 2.0 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.1 | 1.5 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.1 | 0.9 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.1 | 0.5 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
0.1 | 0.3 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
0.1 | 0.4 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
0.1 | 1.4 | GO:0007340 | acrosome reaction(GO:0007340) |
0.1 | 0.3 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 0.3 | GO:0040031 | snRNA modification(GO:0040031) |
0.1 | 0.2 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.1 | 0.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.0 | 0.4 | GO:0030035 | microspike assembly(GO:0030035) |
0.0 | 0.9 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.2 | GO:0051697 | protein delipidation(GO:0051697) |
0.0 | 0.2 | GO:0015868 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
0.0 | 0.6 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
0.0 | 0.1 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
0.0 | 0.1 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.0 | 0.3 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.2 | GO:1900116 | sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.0 | 0.3 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.0 | 0.6 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.1 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.0 | 0.1 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247) |
0.0 | 0.2 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
0.0 | 1.1 | GO:0021884 | forebrain neuron development(GO:0021884) |
0.0 | 0.1 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
0.0 | 0.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 0.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 0.4 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.0 | 0.9 | GO:0008347 | glial cell migration(GO:0008347) |
0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 2.2 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.0 | 0.1 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.0 | 0.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.5 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.7 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.4 | 2.4 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.2 | 1.1 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.2 | 0.8 | GO:1990357 | terminal web(GO:1990357) |
0.2 | 1.9 | GO:0000124 | SAGA complex(GO:0000124) |
0.1 | 1.5 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 4.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.1 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 2.5 | GO:0001741 | XY body(GO:0001741) |
0.1 | 0.9 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 0.7 | GO:0071664 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
0.1 | 0.3 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.1 | 0.9 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.1 | 2.1 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 1.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 2.1 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.1 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 1.5 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 0.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 1.4 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.1 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.0 | 0.2 | GO:0005922 | connexon complex(GO:0005922) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.5 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
0.3 | 2.5 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
0.3 | 1.5 | GO:0071253 | connexin binding(GO:0071253) |
0.3 | 2.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.2 | 0.7 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.2 | 0.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.2 | 2.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.2 | 0.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.1 | 0.9 | GO:0070728 | leucine binding(GO:0070728) |
0.1 | 0.8 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
0.1 | 2.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 1.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.1 | 0.4 | GO:0042806 | fucose binding(GO:0042806) |
0.1 | 2.1 | GO:0035198 | miRNA binding(GO:0035198) |
0.1 | 4.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.1 | 0.3 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.1 | 2.7 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 0.3 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.1 | 3.8 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.1 | 1.5 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.1 | 0.3 | GO:0019808 | polyamine binding(GO:0019808) |
0.1 | 0.9 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 0.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.1 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.0 | 0.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 0.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.0 | 0.7 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 0.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 2.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 0.2 | GO:0036122 | BMP binding(GO:0036122) |
0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.6 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 0.5 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.0 | 1.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.0 | 1.5 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.0 | 0.1 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.6 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.3 | GO:0016208 | AMP binding(GO:0016208) |
0.0 | 3.0 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.1 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.0 | 0.2 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |