Motif ID: Tbx1_Eomes
Z-value: 0.781
Transcription factors associated with Tbx1_Eomes:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Eomes | ENSMUSG00000032446.8 | Eomes |
| Tbx1 | ENSMUSG00000009097.9 | Tbx1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Eomes | mm10_v2_chr9_+_118478344_118478451 | 0.17 | 4.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 165 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 75 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.6 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.8 | 4.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.3 | 3.1 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.1 | 2.9 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.5 | 2.7 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.5 | 2.5 | GO:0030091 | protein repair(GO:0030091) |
| 0.3 | 2.5 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.1 | 2.4 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.2 | 2.2 | GO:0071493 | cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399) |
| 0.0 | 2.2 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.2 | 2.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.2 | 2.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.7 | 2.0 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.1 | 2.0 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.5 | 1.5 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
| 0.4 | 1.5 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.2 | 1.5 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.1 | 1.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 1.5 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.1 | 1.4 | GO:0007340 | acrosome reaction(GO:0007340) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 26 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 2.5 | GO:0001741 | XY body(GO:0001741) |
| 0.4 | 2.4 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.7 | 2.2 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.1 | 2.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 2.1 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 1.9 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 1.5 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 1.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 1.5 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 1.4 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.2 | 1.1 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.1 | 0.9 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.9 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.2 | 0.8 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 0.7 | GO:0071664 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
| 0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.3 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 54 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 3.8 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 3.0 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 2.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 2.7 | GO:0005112 | Notch binding(GO:0005112) |
| 0.4 | 2.5 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 0.3 | 2.5 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
| 0.3 | 2.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.2 | 2.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 2.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 2.1 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.3 | 1.5 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 1.5 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 1.5 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 1.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 1.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.2 | 0.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.1 | 0.9 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 0.9 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
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