Motif ID: Tbx3

Z-value: 0.338


Transcription factors associated with Tbx3:

Gene SymbolEntrez IDGene Name
Tbx3 ENSMUSG00000018604.12 Tbx3



Activity profile for motif Tbx3.

activity profile for motif Tbx3


Sorted Z-values histogram for motif Tbx3

Sorted Z-values for motif Tbx3



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_56377300 1.554 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr10_+_127514939 1.117 ENSMUST00000035735.9
Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_-_31222604 1.034 ENSMUST00000127775.1
4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr14_+_67745229 0.911 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr7_-_4522427 0.840 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr17_-_59013264 0.798 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr11_-_94507337 0.726 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr7_-_4522794 0.621 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr7_-_118443549 0.489 ENSMUST00000081574.4
Syt17
synaptotagmin XVII
chrX_-_20931520 0.342 ENSMUST00000001156.7
Cfp
complement factor properdin
chr7_+_107567445 0.248 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr18_-_23981555 0.232 ENSMUST00000115829.1
Zscan30
zinc finger and SCAN domain containing 30
chr13_+_108046411 0.187 ENSMUST00000095458.4
Smim15
small integral membrane protein 15
chr1_+_93215899 0.180 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr7_-_28949670 0.149 ENSMUST00000148196.1
Actn4
actinin alpha 4
chr12_+_84361636 0.130 ENSMUST00000110276.1
Coq6
coenzyme Q6 homolog (yeast)
chr10_+_80226644 0.118 ENSMUST00000130260.1
Mum1
melanoma associated antigen (mutated) 1
chr12_+_84361968 0.084 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr2_+_154551771 0.072 ENSMUST00000104928.1
Actl10
actin-like 10
chr7_-_44236098 0.067 ENSMUST00000037220.4
1700028J19Rik
RIKEN cDNA 1700028J19 gene
chr4_+_135759705 0.048 ENSMUST00000105854.1
Myom3
myomesin family, member 3
chr16_+_17619341 0.045 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
Smpd4








sphingomyelin phosphodiesterase 4








chr3_+_89246397 0.020 ENSMUST00000168900.1
Krtcap2
keratinocyte associated protein 2
chr5_-_106926245 0.000 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.2 1.5 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 0.8 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 0.9 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.1 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.5 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.6 GO:0005916 fascia adherens(GO:0005916)
0.1 0.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0030172 troponin C binding(GO:0030172)
0.3 1.6 GO:0071253 connexin binding(GO:0071253)
0.0 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)