Motif ID: Tcf21_Msc

Z-value: 1.016

Transcription factors associated with Tcf21_Msc:

Gene SymbolEntrez IDGene Name
Msc ENSMUSG00000025930.5 Msc
Tcf21 ENSMUSG00000045680.7 Tcf21



Activity profile for motif Tcf21_Msc.

activity profile for motif Tcf21_Msc


Sorted Z-values histogram for motif Tcf21_Msc

Sorted Z-values for motif Tcf21_Msc



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf21_Msc

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_106485214 12.786 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chrX_-_106485367 8.034 ENSMUST00000140707.1
 Fndc3c1
fibronectin type III domain containing 3C1
chr2_-_122611238 5.195 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr14_-_20181773 4.488 ENSMUST00000024011.8
 Kcnk5
potassium channel, subfamily K, member 5
chr11_+_99864476 4.199 ENSMUST00000092694.3
 Gm11559
predicted gene 11559
chr14_-_56571830 3.297 ENSMUST00000065302.7
 Cenpj
centromere protein J
chr12_+_109459843 3.064 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr13_+_24327415 3.028 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr6_+_107529717 3.001 ENSMUST00000049285.8
 Lrrn1
leucine rich repeat protein 1, neuronal
chr12_+_52516077 2.827 ENSMUST00000110725.1
 Arhgap5
Rho GTPase activating protein 5
chr2_-_105399286 2.508 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr13_-_100786402 2.438 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr12_-_91779129 2.317 ENSMUST00000170077.1
 Ston2
stonin 2
chr18_+_4994600 2.314 ENSMUST00000140448.1
 Svil
supervillin
chr2_+_30078584 2.232 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chr7_+_122289297 2.219 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr18_+_60293372 2.161 ENSMUST00000171297.1
 F830016B08Rik
RIKEN cDNA F830016B08 gene
chr18_+_73863672 2.126 ENSMUST00000134847.1
 Mro
maestro
chr13_-_71963713 2.096 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr11_-_4118778 2.052 ENSMUST00000003681.7
 Sec14l2
SEC14-like 2 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 215 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.6 3.6 GO:1903887 motile primary cilium assembly(GO:1903887)
0.1 3.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
1.0 3.0 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.9 2.6 GO:0036292 DNA rewinding(GO:0036292)
0.3 2.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 2.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 2.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.6 2.4 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.2 2.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.2 2.3 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 2.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.4 2.2 GO:0035405 histone-threonine phosphorylation(GO:0035405) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 2.1 GO:0030035 microspike assembly(GO:0030035)
0.4 2.0 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.2 1.9 GO:0060539 diaphragm development(GO:0060539)
0.1 1.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.9 GO:0032611 interleukin-1 beta production(GO:0032611)
0.6 1.8 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.6 GO:0005814 centriole(GO:0005814)
0.1 3.2 GO:0043034 costamere(GO:0043034)
0.0 2.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.6 2.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.1 GO:0031526 brush border membrane(GO:0031526)
0.1 2.0 GO:0043596 nuclear replication fork(GO:0043596)
0.4 1.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.8 GO:0034399 nuclear periphery(GO:0034399)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.2 1.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.5 GO:0098536 deuterosome(GO:0098536)
0.0 1.5 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.5 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0005509 calcium ion binding(GO:0005509)
0.2 6.4 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 4.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 3.9 GO:0042169 SH2 domain binding(GO:0042169)
1.0 3.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 2.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 2.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 2.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.6 GO:0051015 actin filament binding(GO:0051015)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 2.4 GO:0005113 patched binding(GO:0005113)
0.3 2.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 2.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.1 GO:0030507 spectrin binding(GO:0030507)
0.0 2.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 2.0 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)