Motif ID: Tcf7l1

Z-value: 0.893


Transcription factors associated with Tcf7l1:

Gene SymbolEntrez IDGene Name
Tcf7l1 ENSMUSG00000055799.7 Tcf7l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72788952_727890610.562.9e-03Click!


Activity profile for motif Tcf7l1.

activity profile for motif Tcf7l1


Sorted Z-values histogram for motif Tcf7l1

Sorted Z-values for motif Tcf7l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf7l1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_70851189 2.793 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr14_-_98169542 2.688 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr11_+_108920800 2.674 ENSMUST00000140821.1
Axin2
axin2
chr3_+_131110350 2.641 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr7_-_49636847 2.045 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr2_+_70474923 1.789 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr7_+_45216671 1.782 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr1_-_183147461 1.760 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr15_+_34238026 1.728 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chrX_-_48034842 1.718 ENSMUST00000039026.7
Apln
apelin
chr2_-_180889660 1.635 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr2_+_173021902 1.399 ENSMUST00000029014.9
Rbm38
RNA binding motif protein 38
chr2_+_173022360 1.355 ENSMUST00000173997.1
Rbm38
RNA binding motif protein 38
chr7_+_100493795 1.323 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr18_-_62756275 1.319 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr11_+_108921648 1.230 ENSMUST00000144511.1
Axin2
axin2
chr9_+_85842852 1.201 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chrX_-_134161928 1.194 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr7_-_144939823 1.187 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr17_-_89910449 1.164 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr18_+_82914632 1.136 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr6_-_148944750 1.107 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr3_-_25212720 1.088 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr6_+_17065129 1.081 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr12_-_54986363 1.074 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr13_-_102905740 1.065 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr8_+_92357787 1.014 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr8_+_108714644 0.996 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr2_+_157560078 0.926 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr4_+_62583568 0.911 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr9_+_119402444 0.910 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr6_+_29735667 0.907 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr14_+_50924968 0.895 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
Apex1


apurinic/apyrimidinic endonuclease 1


chr14_+_27039001 0.874 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr9_-_99876147 0.872 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr19_-_41802028 0.852 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr4_+_115057683 0.834 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr11_+_108920342 0.821 ENSMUST00000052915.7
Axin2
axin2
chr11_-_77725281 0.818 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chrX_+_71556874 0.818 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr19_-_32466575 0.801 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr3_+_32708546 0.772 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr19_+_55895508 0.764 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr10_+_80150448 0.762 ENSMUST00000153477.1
Midn
midnolin
chr2_+_174760619 0.752 ENSMUST00000029030.2
Edn3
endothelin 3
chr9_+_102717668 0.744 ENSMUST00000035121.7
Amotl2
angiomotin-like 2
chr7_+_127233227 0.742 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr7_+_127233044 0.741 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr19_-_47919269 0.732 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr13_-_102906046 0.721 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr10_-_4387436 0.720 ENSMUST00000100077.3
Zbtb2
zinc finger and BTB domain containing 2
chr16_-_17132377 0.707 ENSMUST00000023453.7
Sdf2l1
stromal cell-derived factor 2-like 1
chr19_-_5729618 0.703 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr7_+_67655414 0.696 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr3_-_57575760 0.696 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr7_-_115824699 0.675 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr9_+_107569112 0.656 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr17_-_35697971 0.636 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr10_-_61979073 0.618 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr11_+_117332335 0.617 ENSMUST00000106349.1
Sept9
septin 9
chr12_-_16800674 0.608 ENSMUST00000162112.1
Greb1
gene regulated by estrogen in breast cancer protein
chr2_+_152081529 0.604 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr10_+_11609256 0.604 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr1_+_137928100 0.588 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chrX_+_6415736 0.578 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr18_-_88894203 0.570 ENSMUST00000123826.1
Socs6
suppressor of cytokine signaling 6
chr10_-_4388037 0.567 ENSMUST00000100078.2
Zbtb2
zinc finger and BTB domain containing 2
chr1_-_78968079 0.564 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr15_-_98953541 0.557 ENSMUST00000097014.5
Tuba1a
tubulin, alpha 1A
chr4_-_126468580 0.554 ENSMUST00000097888.3
Ago1
argonaute RISC catalytic subunit 1
chr9_+_35423582 0.545 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr13_-_119408985 0.545 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr8_+_45507768 0.544 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr1_+_110099295 0.528 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr17_+_12119274 0.528 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr12_-_21417526 0.527 ENSMUST00000049531.9
ENSMUST00000155480.1
Ywhaq

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

chr17_+_28691419 0.527 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr12_-_21417591 0.511 ENSMUST00000135088.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr5_+_110135823 0.497 ENSMUST00000112519.2
ENSMUST00000014812.8
Chfr

checkpoint with forkhead and ring finger domains

chr8_+_31111816 0.496 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr5_+_148265307 0.493 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr13_-_41273977 0.491 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr14_-_52020698 0.486 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr19_-_30549516 0.486 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chrX_-_57392962 0.484 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome
chr2_+_163658370 0.478 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr16_+_4968936 0.465 ENSMUST00000090457.5
4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr7_-_105787544 0.458 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr3_-_89998656 0.452 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr12_+_19954505 0.449 ENSMUST00000179133.1
Gm21863
predicted gene, 21863
chr3_-_127837419 0.446 ENSMUST00000051737.6
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr2_-_69586021 0.441 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr11_+_114851507 0.436 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr2_-_165034770 0.434 ENSMUST00000122070.1
ENSMUST00000121377.1
Ncoa5

nuclear receptor coactivator 5

chr11_+_114851814 0.427 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
Gprc5c


G protein-coupled receptor, family C, group 5, member C


chr12_-_98737405 0.425 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr7_+_126760591 0.422 ENSMUST00000091328.2
Mapk3
mitogen-activated protein kinase 3
chr19_-_46338632 0.416 ENSMUST00000051234.8
ENSMUST00000167861.1
Cuedc2

CUE domain containing 2

chr11_+_88068242 0.413 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr6_-_122340525 0.407 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr17_-_47924400 0.404 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr18_-_88894322 0.399 ENSMUST00000070116.5
ENSMUST00000125362.1
Socs6

suppressor of cytokine signaling 6

chr9_+_21616166 0.396 ENSMUST00000034707.8
ENSMUST00000098948.3
Smarca4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr2_-_165034821 0.394 ENSMUST00000153905.1
ENSMUST00000040381.8
Ncoa5

nuclear receptor coactivator 5

chrX_-_57393020 0.392 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
Rbmx


RNA binding motif protein, X chromosome


chr10_+_80151154 0.391 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr5_+_148265202 0.391 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr4_+_132638987 0.389 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
Eya3




eyes absent 3 homolog (Drosophila)




chr12_-_21417356 0.384 ENSMUST00000103002.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr13_-_29984219 0.382 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr6_+_83137089 0.382 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr17_-_47924460 0.379 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr10_+_53596936 0.376 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr7_+_73375494 0.372 ENSMUST00000094312.5
ENSMUST00000119206.1
Rgma

RGM domain family, member A

chr5_+_148265265 0.371 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_-_114380505 0.368 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr7_-_83884289 0.359 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chr6_-_122340499 0.359 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr17_-_34603675 0.356 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr15_-_50890396 0.354 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr5_-_134946917 0.352 ENSMUST00000051401.2
Cldn4
claudin 4
chr4_-_142239356 0.351 ENSMUST00000036476.3
Kazn
kazrin, periplakin interacting protein
chr3_-_57575907 0.350 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr11_-_48946148 0.347 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr18_-_46212595 0.345 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr8_-_122678072 0.333 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr1_+_59482133 0.332 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr10_-_117063764 0.332 ENSMUST00000047672.7
Cct2
chaperonin containing Tcp1, subunit 2 (beta)
chrX_+_169879596 0.330 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr1_+_131153175 0.322 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
Eif2d


eukaryotic translation initiation factor 2D


chr7_-_105787567 0.318 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr2_+_18055203 0.317 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_5894100 0.315 ENSMUST00000055911.4
Tigd3
tigger transposable element derived 3
chr3_-_95106779 0.314 ENSMUST00000005768.7
ENSMUST00000107232.2
ENSMUST00000107236.2
Pip5k1a


phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha


chr2_+_18672384 0.311 ENSMUST00000171845.1
ENSMUST00000061158.4
Commd3

COMM domain containing 3

chr7_-_27195727 0.310 ENSMUST00000163311.2
ENSMUST00000126211.1
Snrpa

small nuclear ribonucleoprotein polypeptide A

chr12_-_83597140 0.306 ENSMUST00000048319.4
Zfyve1
zinc finger, FYVE domain containing 1
chr1_+_136467958 0.304 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr5_-_31193008 0.298 ENSMUST00000114605.1
ENSMUST00000114603.1
Eif2b4

eukaryotic translation initiation factor 2B, subunit 4 delta

chr2_+_27079371 0.298 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr19_-_10604258 0.293 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr10_-_13388830 0.291 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr9_+_110132015 0.288 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr5_-_31193105 0.287 ENSMUST00000166769.1
Eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr1_-_182019927 0.285 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr9_-_66124872 0.276 ENSMUST00000034946.8
Snx1
sorting nexin 1
chr4_+_32983008 0.263 ENSMUST00000098190.3
ENSMUST00000029946.7
Rragd

Ras-related GTP binding D

chr6_+_38918969 0.263 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr1_+_88227005 0.261 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr9_+_65676517 0.256 ENSMUST00000153700.2
ENSMUST00000046490.7
Oaz2

ornithine decarboxylase antizyme 2

chr11_-_6274830 0.256 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chr9_-_35267746 0.253 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b



family with sequence similarity 118, member B



chr5_-_114380459 0.250 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chrX_-_167209149 0.248 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr2_+_35582829 0.247 ENSMUST00000135741.1
Dab2ip
disabled 2 interacting protein
chr5_+_44100442 0.244 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr6_+_86628174 0.238 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr15_-_50889691 0.233 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr10_-_13388753 0.231 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr8_+_107436355 0.227 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr6_-_47813512 0.226 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr17_+_20570362 0.215 ENSMUST00000095633.3
Gm5145
predicted pseudogene 5145
chr5_-_148392810 0.214 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_+_3649759 0.213 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr14_+_70774304 0.212 ENSMUST00000022698.7
Dok2
docking protein 2
chr9_+_65676566 0.211 ENSMUST00000147732.2
ENSMUST00000136166.2
Oaz2

ornithine decarboxylase antizyme 2

chr8_+_79028317 0.210 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr19_-_37330613 0.209 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr17_-_34031684 0.203 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr6_-_122340200 0.198 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr9_-_110117303 0.194 ENSMUST00000136969.1
Dhx30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr13_-_97747373 0.194 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr15_+_81466309 0.190 ENSMUST00000023036.5
Rbx1
ring-box 1
chr5_+_34549595 0.185 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr5_+_31193227 0.185 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
Snx17


sorting nexin 17


chr8_+_79028587 0.183 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr15_-_79328154 0.182 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chr2_+_138278481 0.181 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr12_-_12941827 0.176 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_167932327 0.172 ENSMUST00000029053.7
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr19_+_8839298 0.171 ENSMUST00000160556.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr14_+_34375504 0.169 ENSMUST00000111908.1
Mmrn2
multimerin 2
chr5_+_34549568 0.161 ENSMUST00000118545.1
Sh3bp2
SH3-domain binding protein 2
chr15_-_79328201 0.160 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr17_+_7925990 0.157 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr10_+_80300997 0.156 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr8_-_34146974 0.154 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr4_+_129513581 0.154 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr17_+_37193889 0.154 ENSMUST00000038844.6
Ubd
ubiquitin D
chr12_+_31265234 0.147 ENSMUST00000169088.1
Lamb1
laminin B1
chr19_+_8591254 0.147 ENSMUST00000010251.3
ENSMUST00000170817.1
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr14_-_31019055 0.147 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr9_-_57645561 0.145 ENSMUST00000034863.6
Csk
c-src tyrosine kinase
chr14_-_70766598 0.141 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7

exportin 7

chr18_+_24205937 0.141 ENSMUST00000164998.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr6_+_54039558 0.139 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr8_+_86745679 0.132 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr18_+_24205722 0.131 ENSMUST00000170243.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr9_-_45984816 0.131 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr12_+_113140198 0.119 ENSMUST00000084882.4
Crip2
cysteine rich protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.9 2.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.9 2.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.3 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.9 GO:0060242 contact inhibition(GO:0060242)
0.3 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.3 0.8 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.2 1.7 GO:0051461 positive regulation of heat generation(GO:0031652) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.5 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 2.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 1.0 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2 0.8 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 2.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.7 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.2 1.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.7 GO:0019087 transformation of host cell by virus(GO:0019087)
0.2 1.8 GO:0060539 diaphragm development(GO:0060539)
0.1 0.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.4 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 1.8 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 2.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0001705 ectoderm formation(GO:0001705)
0.1 1.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.8 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 1.7 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.7 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 1.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.2 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.6 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.9 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.4 GO:0045056 transcytosis(GO:0045056)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.1 GO:0009409 response to cold(GO:0009409)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.2 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0006507 GPI anchor release(GO:0006507)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.9 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.6 GO:0050890 cognition(GO:0050890)
0.0 0.5 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.0 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.7 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.9 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 0.8 GO:0033193 Lsd1/2 complex(GO:0033193)
0.2 1.1 GO:0008623 CHRAC(GO:0008623)
0.2 0.7 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.2 3.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.4 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.2 GO:0097443 sorting endosome(GO:0097443)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 10.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 2.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 0.9 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 0.9 GO:0005118 sevenless binding(GO:0005118)
0.2 4.7 GO:0070411 I-SMAD binding(GO:0070411)
0.2 0.9 GO:0005113 patched binding(GO:0005113)
0.2 2.8 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.7 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 2.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.6 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.9 GO:0034711 inhibin binding(GO:0034711)
0.1 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 2.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.7 GO:0001047 core promoter binding(GO:0001047)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)