Motif ID: Tead1

Z-value: 0.598


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112679327_1126793730.423.2e-02Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_34255325 3.114 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr4_-_43558386 1.446 ENSMUST00000130353.1
 Tln1
talin 1
chr2_+_20519776 1.156 ENSMUST00000114604.2
ENSMUST00000066509.3
 Etl4

enhancer trap locus 4

chr11_-_32222233 0.976 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr11_-_5381734 0.964 ENSMUST00000172492.1
 Znrf3
zinc and ring finger 3
chr6_+_17306335 0.937 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr19_-_4439388 0.902 ENSMUST00000117462.1
ENSMUST00000048197.3
 Rhod

ras homolog gene family, member D

chr2_+_91457501 0.761 ENSMUST00000028689.3
 Lrp4
low density lipoprotein receptor-related protein 4
chr3_-_57575760 0.747 ENSMUST00000029380.7
 Wwtr1
WW domain containing transcription regulator 1
chr6_+_146888481 0.694 ENSMUST00000016631.7
ENSMUST00000111623.2
 Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr14_-_54577578 0.675 ENSMUST00000054487.8
 Ajuba
ajuba LIM protein
chr9_-_8004585 0.589 ENSMUST00000086580.5
ENSMUST00000065353.6
 Yap1

yes-associated protein 1

chr8_+_45627946 0.576 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr17_-_71002017 0.565 ENSMUST00000128179.1
ENSMUST00000150456.1
 Myl12a

myosin, light chain 12A, regulatory, non-sarcomeric

chrX_+_101254528 0.558 ENSMUST00000062000.4
 Foxo4
forkhead box O4
chr10_+_93641041 0.552 ENSMUST00000020204.4
 Ntn4
netrin 4
chr12_-_98737405 0.540 ENSMUST00000170188.1
 Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr2_-_90580578 0.532 ENSMUST00000168621.2
 Ptprj
protein tyrosine phosphatase, receptor type, J
chr8_+_45628176 0.504 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr15_+_78842632 0.498 ENSMUST00000059619.1
 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.4 1.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.2 1.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2 1.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 1.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.3 0.8 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 0.8 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.8 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 0.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.7 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.3 GO:0016460 myosin II complex(GO:0016460)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)