Motif ID: Tfap2b

Z-value: 0.463


Transcription factors associated with Tfap2b:

Gene SymbolEntrez IDGene Name
Tfap2b ENSMUSG00000025927.7 Tfap2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2bmm10_v2_chr1_+_19208914_19208967-0.395.1e-02Click!


Activity profile for motif Tfap2b.

activity profile for motif Tfap2b


Sorted Z-values histogram for motif Tfap2b

Sorted Z-values for motif Tfap2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_37824580 0.564 ENSMUST00000063116.9
 Msx1
msh homeobox 1
chr2_+_119742306 0.461 ENSMUST00000028758.7
 Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr7_-_27333602 0.446 ENSMUST00000118583.1
ENSMUST00000118961.1
ENSMUST00000121175.1
 Ltbp4


latent transforming growth factor beta binding protein 4


chr3_-_89279633 0.428 ENSMUST00000118860.1
ENSMUST00000029566.2
 Efna1

ephrin A1

chr6_+_85187438 0.426 ENSMUST00000045942.8
 Emx1
empty spiracles homeobox 1
chr17_-_70849644 0.390 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
 Tgif1


TGFB-induced factor homeobox 1


chr15_-_75747922 0.387 ENSMUST00000062002.4
 Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr4_+_109978004 0.353 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr11_-_59290746 0.349 ENSMUST00000010044.7
 Wnt3a
wingless-related MMTV integration site 3A
chr8_+_105170668 0.321 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
 Cbfb



core binding factor beta



chr1_+_74771886 0.305 ENSMUST00000006716.6
 Wnt6
wingless-related MMTV integration site 6
chr1_-_56978534 0.299 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr13_+_49187485 0.294 ENSMUST00000049022.8
ENSMUST00000120733.1
 Ninj1

ninjurin 1

chr9_+_119052770 0.287 ENSMUST00000051386.6
ENSMUST00000074734.6
 Vill

villin-like

chr11_+_35121126 0.286 ENSMUST00000069837.3
 Slit3
slit homolog 3 (Drosophila)
chr19_+_5740885 0.283 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr4_+_46450892 0.281 ENSMUST00000102926.4
 Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_-_65238625 0.275 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
 Cobll1


Cobl-like 1


chr8_+_84723003 0.274 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chrX_+_9272756 0.268 ENSMUST00000015486.6
 Xk
Kell blood group precursor (McLeod phenotype) homolog

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.1 0.4 GO:0014028 notochord formation(GO:0014028)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) negative regulation of dopaminergic neuron differentiation(GO:1904339) regulation of cardiac cell fate specification(GO:2000043)
0.1 0.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.0 0.3 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)