Motif ID: Tfcp2

Z-value: 1.874


Transcription factors associated with Tfcp2:

Gene SymbolEntrez IDGene Name
Tfcp2 ENSMUSG00000009733.8 Tfcp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_1005520100.481.3e-02Click!


Activity profile for motif Tfcp2.

activity profile for motif Tfcp2


Sorted Z-values histogram for motif Tfcp2

Sorted Z-values for motif Tfcp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_57511833 8.500 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr11_-_22001605 6.898 ENSMUST00000006071.7
 Otx1
orthodenticle homolog 1 (Drosophila)
chr6_+_5390387 6.623 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr16_-_26989974 6.384 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr18_+_11633276 6.020 ENSMUST00000115861.2
 Rbbp8
retinoblastoma binding protein 8
chr11_+_69045640 5.666 ENSMUST00000108666.1
ENSMUST00000021277.5
 Aurkb

aurora kinase B

chr10_-_42583628 5.533 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr12_-_91779129 5.510 ENSMUST00000170077.1
 Ston2
stonin 2
chr2_-_5012716 5.149 ENSMUST00000027980.7
 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr12_+_24708984 4.992 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr1_+_44551483 4.958 ENSMUST00000074525.3
 Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr18_+_60925612 4.860 ENSMUST00000102888.3
ENSMUST00000025519.4
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr14_-_21989475 4.715 ENSMUST00000043409.7
 Zfp503
zinc finger protein 503
chr8_+_69822429 4.509 ENSMUST00000164890.1
ENSMUST00000034325.4
 Lpar2

lysophosphatidic acid receptor 2

chr11_-_89302545 4.307 ENSMUST00000061728.3
 Nog
noggin
chr5_+_92809372 4.255 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr1_+_44551650 4.208 ENSMUST00000160854.1
 Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr2_-_102186322 4.206 ENSMUST00000111222.1
ENSMUST00000058790.5
 Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr13_-_100786402 4.179 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr5_-_100500592 4.165 ENSMUST00000149714.1
ENSMUST00000046154.5
 Lin54

lin-54 homolog (C. elegans)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 13.4 GO:0006270 DNA replication initiation(GO:0006270)
2.0 9.8 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.2 8.8 GO:0006911 phagocytosis, engulfment(GO:0006911)
1.2 8.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.5 7.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.8 7.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.9 6.9 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 6.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.3 6.7 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.7 6.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 6.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 6.1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.2 6.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
1.1 5.5 GO:0021764 amygdala development(GO:0021764)
1.2 4.8 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.6 4.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 4.6 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.2 4.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
1.1 4.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.4 4.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.3 GO:0005615 extracellular space(GO:0005615)
0.1 8.5 GO:0000793 condensed chromosome(GO:0000793)
0.2 7.7 GO:0032839 dendrite cytoplasm(GO:0032839)
1.7 6.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 6.6 GO:0030027 lamellipodium(GO:0030027)
0.1 6.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 6.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 6.0 GO:0005912 adherens junction(GO:0005912)
1.1 5.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 5.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.9 5.1 GO:0031298 replication fork protection complex(GO:0031298)
0.6 4.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.9 4.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.0 4.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 3.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 3.7 GO:0030139 endocytic vesicle(GO:0030139)
0.4 3.6 GO:0005642 annulate lamellae(GO:0005642)
0.2 3.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 3.1 GO:0030863 cortical cytoskeleton(GO:0030863)
0.5 2.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.8 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 10.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
1.4 8.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 7.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 7.7 GO:0032794 GTPase activating protein binding(GO:0032794)
1.4 7.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 7.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.6 6.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.8 5.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 5.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.6 5.1 GO:0003688 DNA replication origin binding(GO:0003688)
1.6 4.8 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.4 4.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.9 4.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 4.3 GO:0019955 cytokine binding(GO:0019955)
0.8 4.2 GO:0005113 patched binding(GO:0005113)
0.0 4.2 GO:0003682 chromatin binding(GO:0003682)
0.0 4.1 GO:0030165 PDZ domain binding(GO:0030165)
0.2 4.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)