Motif ID: Tfdp1_Wt1_Egr2

Z-value: 1.829

Transcription factors associated with Tfdp1_Wt1_Egr2:

Gene SymbolEntrez IDGene Name
Egr2 ENSMUSG00000037868.9 Egr2
Tfdp1 ENSMUSG00000038482.10 Tfdp1
Wt1 ENSMUSG00000016458.7 Wt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfdp1mm10_v2_chr8_+_13339656_133396740.628.1e-04Click!
Egr2mm10_v2_chr10_+_67537861_67537930-0.321.1e-01Click!


Activity profile for motif Tfdp1_Wt1_Egr2.

activity profile for motif Tfdp1_Wt1_Egr2


Sorted Z-values histogram for motif Tfdp1_Wt1_Egr2

Sorted Z-values for motif Tfdp1_Wt1_Egr2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfdp1_Wt1_Egr2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_48261427 10.717 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr9_-_119578981 6.827 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chr13_-_29984219 6.320 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr4_-_3938354 5.957 ENSMUST00000003369.3
 Plag1
pleiomorphic adenoma gene 1
chr4_-_97778042 5.533 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_156839790 5.434 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr6_+_120666388 5.425 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr10_-_120476469 5.388 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr16_-_22163299 5.258 ENSMUST00000100052.4
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chrX_-_162159717 5.115 ENSMUST00000087085.3
 Nhs
Nance-Horan syndrome (human)
chr3_-_8667033 5.075 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_-_12037391 4.900 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10
chr7_-_38107490 4.768 ENSMUST00000108023.3
 Ccne1
cyclin E1
chr4_+_8691303 4.670 ENSMUST00000051558.3
 Chd7
chromodomain helicase DNA binding protein 7
chr17_-_70851189 4.635 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr7_+_117380937 4.514 ENSMUST00000032892.5
 Xylt1
xylosyltransferase 1
chr2_+_168081004 4.464 ENSMUST00000052125.6
 Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr5_+_77265454 4.330 ENSMUST00000080359.5
 Rest
RE1-silencing transcription factor
chr14_+_122475397 4.315 ENSMUST00000075888.5
 Zic2
zinc finger protein of the cerebellum 2
chr1_-_9700209 4.247 ENSMUST00000088658.4
 Mybl1
myeloblastosis oncogene-like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,104 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 19.9 GO:0006270 DNA replication initiation(GO:0006270)
0.9 14.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.3 14.1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.3 12.8 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 12.3 GO:0008380 RNA splicing(GO:0008380)
0.3 10.7 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.1 10.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 10.2 GO:0006281 DNA repair(GO:0006281)
3.3 9.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.4 9.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 9.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.3 9.7 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 9.7 GO:0051028 mRNA transport(GO:0051028)
1.1 9.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.3 9.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
1.2 8.7 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.8 8.7 GO:0060736 prostate gland growth(GO:0060736)
2.9 8.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.8 8.6 GO:0030903 notochord development(GO:0030903)
2.1 8.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 332 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 143.2 GO:0005634 nucleus(GO:0005634)
0.1 109.5 GO:0005654 nucleoplasm(GO:0005654)
0.1 35.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 28.3 GO:0000228 nuclear chromosome(GO:0000228)
0.4 27.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 18.9 GO:0005681 spliceosomal complex(GO:0005681)
0.4 17.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 17.0 GO:0005814 centriole(GO:0005814)
0.1 16.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.3 16.2 GO:0005844 polysome(GO:0005844)
0.2 15.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 15.5 GO:0005694 chromosome(GO:0005694)
0.2 15.2 GO:0005643 nuclear pore(GO:0005643)
0.3 11.9 GO:0016592 mediator complex(GO:0016592)
0.9 11.3 GO:0043219 lateral loop(GO:0043219)
0.3 10.7 GO:0005876 spindle microtubule(GO:0005876)
0.5 10.2 GO:0016580 Sin3 complex(GO:0016580)
1.7 10.0 GO:0061689 tricellular tight junction(GO:0061689)
0.2 8.6 GO:0000922 spindle pole(GO:0000922)
1.2 8.1 GO:0001940 male pronucleus(GO:0001940)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 555 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 79.8 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.3 31.2 GO:0001047 core promoter binding(GO:0001047)
0.3 27.1 GO:0042393 histone binding(GO:0042393)
0.0 26.8 GO:0044822 poly(A) RNA binding(GO:0044822)
0.0 25.0 GO:0003677 DNA binding(GO:0003677)
0.3 18.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 18.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.3 16.2 GO:0035064 methylated histone binding(GO:0035064)
0.5 15.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 13.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.8 13.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.3 12.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 12.3 GO:0003682 chromatin binding(GO:0003682)
0.3 11.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 10.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 10.8 GO:0003729 mRNA binding(GO:0003729)
0.7 10.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 10.5 GO:0070410 co-SMAD binding(GO:0070410)
0.5 10.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.5 10.1 GO:0070064 proline-rich region binding(GO:0070064)