Motif ID: Tgif1_Meis3

Z-value: 3.370

Transcription factors associated with Tgif1_Meis3:

Gene SymbolEntrez IDGene Name
Meis3 ENSMUSG00000041420.12 Meis3
Tgif1 ENSMUSG00000047407.11 Tgif1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tgif1mm10_v2_chr17_-_70851710_70851738-0.962.5e-14Click!
Meis3mm10_v2_chr7_+_16175085_161751390.627.0e-04Click!


Activity profile for motif Tgif1_Meis3.

activity profile for motif Tgif1_Meis3


Sorted Z-values histogram for motif Tgif1_Meis3

Sorted Z-values for motif Tgif1_Meis3



Network of associatons between targets according to the STRING database.



First level regulatory network of Tgif1_Meis3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66831625 25.673 ENSMUST00000164163.1
 Sla
src-like adaptor
chr7_+_49246131 25.289 ENSMUST00000064395.6
 Nav2
neuron navigator 2
chr4_-_64046925 23.598 ENSMUST00000107377.3
 Tnc
tenascin C
chr15_-_66801577 20.886 ENSMUST00000168589.1
 Sla
src-like adaptor
chr1_-_132542934 16.181 ENSMUST00000086521.4
 Cntn2
contactin 2
chr8_+_70501116 14.295 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr3_+_26331150 13.676 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr15_+_18818895 12.814 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr8_+_57455898 12.452 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr6_-_88874045 12.329 ENSMUST00000038409.5
 Podxl2
podocalyxin-like 2
chr4_+_102254993 12.080 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr7_+_49246812 11.594 ENSMUST00000184945.1
 Nav2
neuron navigator 2
chr7_-_97417730 11.174 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr11_+_98348404 10.868 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr8_-_84800024 10.839 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr6_+_115675983 9.731 ENSMUST00000068960.9
 D830050J10Rik
RIKEN cDNA D830050J10 gene
chr19_+_23758819 9.675 ENSMUST00000025830.7
 Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr16_-_18621366 9.476 ENSMUST00000051160.2
 Gp1bb
glycoprotein Ib, beta polypeptide
chr18_-_66291770 9.409 ENSMUST00000130300.1
 Ccbe1
collagen and calcium binding EGF domains 1
chr3_-_116968969 9.310 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 534 entries
Log-likelihood per target Total log-likelihoodTermDescription
9.2 36.9 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
2.2 28.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
5.9 23.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.5 22.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.7 21.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.8 16.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
4.0 16.2 GO:0031133 regulation of axon diameter(GO:0031133)
2.3 16.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 15.8 GO:0006376 mRNA splice site selection(GO:0006376)
2.5 14.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 14.4 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
1.1 13.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.0 12.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 12.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.3 12.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 11.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.9 11.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.3 10.9 GO:0050435 beta-amyloid metabolic process(GO:0050435)
1.2 10.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
3.5 10.6 GO:0007521 muscle cell fate determination(GO:0007521)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 215 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 123.2 GO:0016021 integral component of membrane(GO:0016021)
0.1 69.8 GO:0005768 endosome(GO:0005768)
3.9 62.7 GO:0005614 interstitial matrix(GO:0005614)
0.2 45.9 GO:0045211 postsynaptic membrane(GO:0045211)
1.1 26.7 GO:0071565 nBAF complex(GO:0071565)
1.1 25.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 17.7 GO:0005581 collagen trimer(GO:0005581)
0.9 17.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 16.3 GO:0043197 dendritic spine(GO:0043197)
0.2 13.9 GO:0031594 neuromuscular junction(GO:0031594)
0.5 13.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.2 13.0 GO:0043083 synaptic cleft(GO:0043083)
4.1 12.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.8 12.3 GO:0043205 fibril(GO:0043205)
0.1 11.4 GO:0030424 axon(GO:0030424)
0.4 11.3 GO:0043194 axon initial segment(GO:0043194)
0.1 11.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.0 11.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.9 11.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.0 11.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 356 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 42.8 GO:0030552 cAMP binding(GO:0030552)
0.3 27.9 GO:0008201 heparin binding(GO:0008201)
3.9 23.6 GO:0045545 syndecan binding(GO:0045545)
0.2 21.5 GO:0001948 glycoprotein binding(GO:0001948)
0.2 21.5 GO:0017124 SH3 domain binding(GO:0017124)
0.2 18.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.0 17.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 16.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 16.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.5 16.1 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.1 15.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.4 14.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 14.7 GO:0005509 calcium ion binding(GO:0005509)
0.7 13.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
3.1 12.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.5 12.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.8 12.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.2 11.9 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 11.4 GO:0003924 GTPase activity(GO:0003924)
0.1 11.3 GO:0017137 Rab GTPase binding(GO:0017137)