Motif ID: Tgif2_Tgif2lx1_Tgif2lx2

Z-value: 0.585

Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2:

Gene SymbolEntrez IDGene Name
Tgif2 ENSMUSG00000062175.7 Tgif2
Tgif2lx1 ENSMUSG00000061283.4 Tgif2lx1
Tgif2lx2 ENSMUSG00000063242.6 Tgif2lx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tgif2mm10_v2_chr2_+_156840966_156841017-0.193.4e-01Click!


Activity profile for motif Tgif2_Tgif2lx1_Tgif2lx2.

activity profile for motif Tgif2_Tgif2lx1_Tgif2lx2


Sorted Z-values histogram for motif Tgif2_Tgif2lx1_Tgif2lx2

Sorted Z-values for motif Tgif2_Tgif2lx1_Tgif2lx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tgif2_Tgif2lx1_Tgif2lx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 163 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_19103022 4.049 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr11_+_98348404 1.524 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_82053222 1.431 ENSMUST00000047527.7
 Zfp804a
zinc finger protein 804A
chr16_+_19028232 1.419 ENSMUST00000074116.4
 Gm10088
predicted gene 10088
chr3_+_102010138 1.349 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr6_-_88875035 1.300 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr18_+_78349754 0.993 ENSMUST00000164064.1
 Gm6133
predicted gene 6133
chr6_-_88874597 0.977 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
 Podxl2


podocalyxin-like 2


chr13_+_54949388 0.967 ENSMUST00000026994.7
ENSMUST00000109994.2
 Unc5a

unc-5 homolog A (C. elegans)

chr5_-_100159261 0.960 ENSMUST00000139520.1
 Tmem150c
transmembrane protein 150C
chr1_+_75450699 0.915 ENSMUST00000037708.9
 Asic4
acid-sensing (proton-gated) ion channel family member 4
chr1_+_75450436 0.904 ENSMUST00000113577.1
 Asic4
acid-sensing (proton-gated) ion channel family member 4
chr15_-_33687840 0.867 ENSMUST00000042021.3
 Tspyl5
testis-specific protein, Y-encoded-like 5
chr15_+_85510812 0.866 ENSMUST00000079690.2
 Gm4825
predicted pseudogene 4825
chr3_-_78892451 0.747 ENSMUST00000164923.1
 Gm5277
predicted gene 5277
chr17_+_87025550 0.744 ENSMUST00000024959.3
ENSMUST00000160269.1
 Cript

cysteine-rich PDZ-binding protein

chr11_+_32000452 0.725 ENSMUST00000020537.2
ENSMUST00000109409.1
 Nsg2

neuron specific gene family member 2

chr13_-_76385028 0.717 ENSMUST00000099365.1
 Gm10760
predicted gene 10760
chr12_+_112999964 0.622 ENSMUST00000180971.1
 9230104M06Rik
RIKEN cDNA 9230104M06 gene
chr9_+_44134562 0.608 ENSMUST00000034650.8
ENSMUST00000098852.2
 Mcam

melanoma cell adhesion molecule


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 GO:0030901 midbrain development(GO:0030901)
0.1 2.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.5 1.5 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.3 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.7 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 0.5 GO:0071873 response to norepinephrine(GO:0071873)
0.2 0.5 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.3 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.3 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.3 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793) membrane hyperpolarization(GO:0060081)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0005272 sodium channel activity(GO:0005272)
0.5 1.5 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.2 1.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)