Motif ID: Thra

Z-value: 0.896


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98753512_98753586-0.882.1e-09Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_141214080 4.341 ENSMUST00000026573.5
ENSMUST00000170841.1
 1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr1_+_84839833 4.329 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chrX_-_143827391 3.941 ENSMUST00000087316.5
 Capn6
calpain 6
chr4_+_44300876 3.812 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr18_+_57142782 3.790 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr5_-_116422858 2.903 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr17_+_85620816 2.879 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr1_-_84839304 2.871 ENSMUST00000027421.6
 Trip12
thyroid hormone receptor interactor 12
chr13_+_44729794 2.794 ENSMUST00000172830.1
 Jarid2
jumonji, AT rich interactive domain 2
chr14_-_118706180 2.769 ENSMUST00000036554.6
ENSMUST00000166646.1
 Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr12_+_79029150 2.743 ENSMUST00000039928.5
 Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr11_+_69965396 2.569 ENSMUST00000018713.6
 Cldn7
claudin 7
chr1_+_131910458 2.397 ENSMUST00000062264.6
 Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr6_+_113531675 2.227 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr11_-_40733373 2.212 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr12_+_112678803 2.116 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
 Zbtb42


zinc finger and BTB domain containing 42


chr1_-_163994767 2.086 ENSMUST00000097493.3
ENSMUST00000045876.6
 BC055324

cDNA sequence BC055324

chr7_+_19083842 2.065 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
 Dmpk



dystrophia myotonica-protein kinase



chr4_-_137766474 2.055 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr5_+_110839973 2.052 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.0 GO:0051028 mRNA transport(GO:0051028)
0.1 4.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.4 4.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.0 3.9 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.0 3.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.8 3.8 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.1 3.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
1.0 2.9 GO:0097402 neuroblast migration(GO:0097402)
1.0 2.9 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 2.8 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 2.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 2.5 GO:0043297 apical junction assembly(GO:0043297)
0.2 2.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 2.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.4 2.2 GO:1903753 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) hard palate development(GO:0060022) negative regulation of p38MAPK cascade(GO:1903753)
0.3 2.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.5 2.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 2.1 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.9 GO:0007296 vitellogenesis(GO:0007296)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 3.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.9 GO:0000776 kinetochore(GO:0000776)
0.2 3.8 GO:0001891 phagocytic cup(GO:0001891)
0.3 3.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 3.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.9 2.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 2.3 GO:0000922 spindle pole(GO:0000922)
0.4 2.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.2 GO:0000793 condensed chromosome(GO:0000793)
0.1 2.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.3 1.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.1 1.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 4.1 GO:0032452 histone demethylase activity(GO:0032452)
0.4 4.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 4.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 3.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 2.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 2.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 2.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 2.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 2.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 1.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 1.6 GO:0043495 protein anchor(GO:0043495)
0.1 1.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.5 GO:0050693 LBD domain binding(GO:0050693)