Motif ID: Tlx1

Z-value: 1.046


Transcription factors associated with Tlx1:

Gene SymbolEntrez IDGene Name
Tlx1 ENSMUSG00000025215.9 Tlx1



Activity profile for motif Tlx1.

activity profile for motif Tlx1


Sorted Z-values histogram for motif Tlx1

Sorted Z-values for motif Tlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_43730593 6.308 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr4_+_48045144 5.928 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr1_-_56969864 5.399 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr7_+_130936172 5.057 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr6_+_54681687 4.410 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr7_-_97417730 4.264 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr12_-_78983476 3.970 ENSMUST00000070174.7
Tmem229b
transmembrane protein 229B
chr6_+_135362931 3.804 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr1_+_185454803 3.623 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr2_-_25470031 3.549 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr18_-_78206408 3.455 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr16_+_90831113 3.410 ENSMUST00000037539.7
ENSMUST00000099543.3
Eva1c

eva-1 homolog C (C. elegans)

chr11_-_116654245 3.388 ENSMUST00000021166.5
Cygb
cytoglobin
chr8_-_109251698 3.140 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr18_-_78123324 2.985 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr6_+_55452177 2.941 ENSMUST00000167484.1
Adcyap1r1
adenylate cyclase activating polypeptide 1 receptor 1
chr3_-_85746266 2.888 ENSMUST00000118408.1
Fam160a1
family with sequence similarity 160, member A1
chr14_+_65970610 2.862 ENSMUST00000127387.1
Clu
clusterin
chr3_+_54156039 2.809 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr13_+_16011851 2.793 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr14_+_65971049 2.720 ENSMUST00000128539.1
Clu
clusterin
chr8_-_94876269 2.672 ENSMUST00000046461.7
Dok4
docking protein 4
chr3_+_123267445 2.650 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr5_+_16553488 2.591 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr14_+_65970804 2.588 ENSMUST00000138191.1
Clu
clusterin
chr13_+_54949388 2.584 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr2_-_104257400 2.516 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr14_+_65971164 2.507 ENSMUST00000144619.1
Clu
clusterin
chr17_+_8340710 2.488 ENSMUST00000163887.1
Prr18
proline rich region 18
chr11_+_97450136 2.382 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr6_+_55451978 2.319 ENSMUST00000070736.5
ENSMUST00000070756.5
ENSMUST00000166962.1
Adcyap1r1


adenylate cyclase activating polypeptide 1 receptor 1


chr2_+_82053222 2.168 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr1_-_162859684 2.136 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chrX_-_73880831 2.110 ENSMUST00000102871.3
L1cam
L1 cell adhesion molecule
chr1_+_172341197 2.105 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr2_+_118663235 2.070 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_+_95692212 2.041 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr9_-_53610329 2.020 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr2_-_164404606 2.001 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4


matrilin 4


chr3_+_156562141 1.972 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr1_+_136131382 1.969 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr6_-_115251839 1.950 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr2_-_168734236 1.865 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chr16_+_20696175 1.858 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr19_-_5924797 1.832 ENSMUST00000055458.4
Cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr9_-_79718631 1.796 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr12_-_112511136 1.784 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr1_-_126830632 1.740 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr5_-_115194283 1.726 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr7_-_80403315 1.706 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr4_+_47208005 1.685 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr9_-_79718518 1.671 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr5_-_122050102 1.663 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr9_-_79718720 1.631 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr5_-_77115145 1.571 ENSMUST00000081964.5
Hopx
HOP homeobox
chr2_+_149830840 1.546 ENSMUST00000109934.1
ENSMUST00000140870.1
Syndig1

synapse differentiation inducing 1

chr5_-_84417359 1.522 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr7_-_4844665 1.499 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr10_-_62340514 1.492 ENSMUST00000099691.4
Hk1
hexokinase 1
chr11_-_89060697 1.464 ENSMUST00000000285.2
Dgke
diacylglycerol kinase, epsilon
chr1_+_91179822 1.461 ENSMUST00000097648.4
ENSMUST00000165855.1
Ramp1

receptor (calcitonin) activity modifying protein 1

chr9_-_78108587 1.443 ENSMUST00000162625.1
ENSMUST00000159099.1
Fbxo9

f-box protein 9

chr4_+_136284708 1.436 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr17_-_46144156 1.425 ENSMUST00000024762.2
Rsph9
radial spoke head 9 homolog (Chlamydomonas)
chr7_+_78578830 1.411 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr5_-_67815852 1.398 ENSMUST00000141443.1
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr2_+_149830788 1.397 ENSMUST00000109935.1
Syndig1
synapse differentiation inducing 1
chr13_+_43785107 1.343 ENSMUST00000015540.2
Cd83
CD83 antigen
chr17_-_25837082 1.321 ENSMUST00000183929.1
ENSMUST00000184865.1
ENSMUST00000026831.7
Rhbdl1


rhomboid, veinlet-like 1 (Drosophila)


chr17_+_6106880 1.259 ENSMUST00000149756.1
Tulp4
tubby like protein 4
chr19_+_32619997 1.220 ENSMUST00000025833.6
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr9_-_99436687 1.179 ENSMUST00000035045.8
Mras
muscle and microspikes RAS
chr2_+_149830894 1.177 ENSMUST00000137280.1
ENSMUST00000149705.1
Syndig1

synapse differentiation inducing 1

chr14_-_30008817 1.174 ENSMUST00000122205.1
ENSMUST00000016110.6
Il17rb

interleukin 17 receptor B

chr9_+_109931774 1.168 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr11_-_118355496 1.164 ENSMUST00000017610.3
Timp2
tissue inhibitor of metalloproteinase 2
chr4_-_136956784 1.149 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr9_+_21165714 1.137 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr2_-_164833438 1.097 ENSMUST00000042775.4
Neurl2
neuralized-like 2 (Drosophila)
chr9_-_78108617 1.080 ENSMUST00000085311.6
Fbxo9
f-box protein 9
chr4_+_136284658 1.075 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr14_+_51091077 1.056 ENSMUST00000022428.5
ENSMUST00000171688.1
Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr4_-_155992604 1.051 ENSMUST00000052185.3
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr2_+_127336152 1.041 ENSMUST00000028846.6
Dusp2
dual specificity phosphatase 2
chr1_+_176814660 1.016 ENSMUST00000056773.8
ENSMUST00000027785.8
Sdccag8

serologically defined colon cancer antigen 8

chr14_-_63177793 1.011 ENSMUST00000054963.9
Fdft1
farnesyl diphosphate farnesyl transferase 1
chr9_-_99436749 1.009 ENSMUST00000122384.1
Mras
muscle and microspikes RAS
chr16_-_76373827 1.004 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr2_+_178193075 0.999 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr19_-_5098418 0.988 ENSMUST00000025805.6
Cnih2
cornichon homolog 2 (Drosophila)
chr9_+_44773027 0.964 ENSMUST00000125877.1
Ift46
intraflagellar transport 46
chr2_-_114052804 0.962 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr3_+_89715016 0.945 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr17_-_25919506 0.930 ENSMUST00000164982.1
ENSMUST00000179998.1
ENSMUST00000167626.1
ENSMUST00000164738.1
ENSMUST00000026826.7
ENSMUST00000167018.1
Rab40c





Rab40c, member RAS oncogene family





chr2_+_30982279 0.916 ENSMUST00000102849.4
Usp20
ubiquitin specific peptidase 20
chr5_+_137758133 0.916 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr4_-_154160632 0.873 ENSMUST00000105639.3
ENSMUST00000030896.8
Tprgl

transformation related protein 63 regulated like

chr11_+_97798995 0.868 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr16_-_17144415 0.859 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr7_+_29309429 0.851 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr17_+_24470393 0.846 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr7_+_28180272 0.832 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr3_+_96601084 0.826 ENSMUST00000062058.3
Lix1l
Lix1-like
chr9_-_15301555 0.793 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chrX_+_73228272 0.790 ENSMUST00000105111.2
F8a
factor 8-associated gene A
chr11_-_75422586 0.788 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr1_-_25829511 0.758 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr6_+_4903298 0.750 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr16_-_18426372 0.738 ENSMUST00000000335.4
Comt
catechol-O-methyltransferase
chr5_+_34549568 0.737 ENSMUST00000118545.1
Sh3bp2
SH3-domain binding protein 2
chr13_+_64432479 0.733 ENSMUST00000021939.6
Cdk20
cyclin-dependent kinase 20
chr10_+_69785507 0.732 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chr9_-_78109020 0.718 ENSMUST00000001402.7
Fbxo9
f-box protein 9
chr6_-_24956106 0.716 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr10_+_86302854 0.707 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr18_-_24709348 0.704 ENSMUST00000067987.1
Gm9955
predicted gene 9955
chrX_-_7574120 0.689 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr11_+_3488275 0.632 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr11_+_116657106 0.608 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr6_-_24515036 0.600 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr9_+_120492606 0.599 ENSMUST00000007139.4
Eif1b
eukaryotic translation initiation factor 1B
chr7_+_113765998 0.593 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr7_+_27447978 0.590 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr8_+_122611618 0.589 ENSMUST00000015157.8
Trappc2l
trafficking protein particle complex 2-like
chr5_+_129501223 0.586 ENSMUST00000053737.7
Sfswap
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr18_-_33464007 0.584 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr9_-_106447584 0.580 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
Abhd14a


abhydrolase domain containing 14A


chr11_-_75422524 0.570 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr7_-_127935429 0.570 ENSMUST00000141385.1
ENSMUST00000156152.1
Prss36

protease, serine, 36

chr3_-_104511812 0.565 ENSMUST00000046316.6
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr1_-_87573825 0.562 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr1_-_172206684 0.561 ENSMUST00000155109.1
Pea15a
phosphoprotein enriched in astrocytes 15A
chr10_+_81137953 0.559 ENSMUST00000117956.1
Zbtb7a
zinc finger and BTB domain containing 7a
chr4_-_147848358 0.534 ENSMUST00000105718.1
ENSMUST00000135798.1
Zfp933

zinc finger protein 933

chr17_+_17064113 0.530 ENSMUST00000127027.1
Zfp960
zinc finger protein 960
chr5_+_34549595 0.527 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr3_-_63964659 0.523 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr9_+_44773191 0.520 ENSMUST00000147559.1
Ift46
intraflagellar transport 46
chr19_+_4878671 0.520 ENSMUST00000006632.7
Zdhhc24
zinc finger, DHHC domain containing 24
chr6_+_4903350 0.511 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr9_+_104566677 0.503 ENSMUST00000157006.1
Cpne4
copine IV
chr17_+_32685610 0.502 ENSMUST00000168171.1
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr8_-_70353243 0.499 ENSMUST00000075666.6
Upf1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr2_+_120629113 0.499 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr5_-_137533297 0.493 ENSMUST00000111020.1
ENSMUST00000111023.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr17_+_17121415 0.492 ENSMUST00000147630.1
Zfp97
zinc finger protein 97
chr5_-_131538687 0.492 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr7_+_62476306 0.492 ENSMUST00000097132.3
Atp5l-ps1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr12_-_84148449 0.468 ENSMUST00000061425.2
Pnma1
paraneoplastic antigen MA1
chr1_-_37865040 0.464 ENSMUST00000041815.8
Tsga10
testis specific 10
chr16_-_14317319 0.461 ENSMUST00000120707.1
ENSMUST00000023357.7
Fopnl

Fgfr1op N-terminal like

chr4_-_140617062 0.454 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_-_155692317 0.452 ENSMUST00000103140.4
Trpc4ap
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr3_+_57736056 0.449 ENSMUST00000041826.9
Rnf13
ring finger protein 13
chr17_+_34969912 0.437 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr7_+_28180226 0.435 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_-_150362708 0.435 ENSMUST00000051153.5
3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr2_-_155692376 0.431 ENSMUST00000041059.5
Trpc4ap
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr4_-_35225789 0.417 ENSMUST00000108126.1
ENSMUST00000108127.3
3110043O21Rik

RIKEN cDNA 3110043O21 gene

chr10_+_112928501 0.400 ENSMUST00000180464.1
Gm26596
predicted gene, 26596
chr2_+_106693185 0.399 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr2_+_49787675 0.398 ENSMUST00000028103.6
Lypd6b
LY6/PLAUR domain containing 6B
chr8_-_104641666 0.394 ENSMUST00000093234.4
Fam96b
family with sequence similarity 96, member B
chr13_+_4191163 0.387 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr2_+_177080256 0.384 ENSMUST00000134614.1
ENSMUST00000108968.1
Gm14401

predicted gene 14401

chr1_-_79440039 0.375 ENSMUST00000049972.4
Scg2
secretogranin II
chr7_-_134232005 0.367 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr8_+_84415348 0.359 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr2_-_150136641 0.352 ENSMUST00000094538.5
ENSMUST00000109931.1
ENSMUST00000089207.6
Zfp120


zinc finger protein 120


chr11_+_120598532 0.337 ENSMUST00000093140.4
Anapc11
anaphase promoting complex subunit 11
chr2_+_175010241 0.332 ENSMUST00000109069.1
ENSMUST00000109070.2
Gm14444

predicted gene 14444

chr4_-_93335510 0.331 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr1_-_126830786 0.324 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr3_-_63964768 0.323 ENSMUST00000029402.8
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr19_+_5447692 0.322 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr12_+_71048338 0.320 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr10_+_96136603 0.312 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr2_+_112284561 0.304 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr5_-_146963742 0.300 ENSMUST00000125217.1
ENSMUST00000110564.1
ENSMUST00000066675.3
ENSMUST00000016654.2
ENSMUST00000110566.1
ENSMUST00000140526.1
Mtif3





mitochondrial translational initiation factor 3





chrX_+_36112110 0.297 ENSMUST00000033418.7
Il13ra1
interleukin 13 receptor, alpha 1
chr16_-_48993931 0.295 ENSMUST00000114516.1
Dzip3
DAZ interacting protein 3, zinc finger
chr12_+_102128718 0.294 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr11_-_97150025 0.293 ENSMUST00000118375.1
Tbkbp1
TBK1 binding protein 1
chr17_+_32621319 0.289 ENSMUST00000077639.5
Gm9705
predicted gene 9705
chr2_-_180225812 0.283 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr9_+_121710389 0.281 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr16_+_32673144 0.280 ENSMUST00000115122.2
ENSMUST00000115120.1
ENSMUST00000131238.1
ENSMUST00000115121.2
ENSMUST00000152361.1
Tnk2




tyrosine kinase, non-receptor, 2




chr16_-_48994081 0.277 ENSMUST00000121869.1
Dzip3
DAZ interacting protein 3, zinc finger
chr11_-_5741141 0.275 ENSMUST00000140922.1
ENSMUST00000093362.5
Urgcp

upregulator of cell proliferation

chr6_+_17306335 0.266 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr1_+_139422196 0.259 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr17_+_32685655 0.255 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr9_+_50856924 0.240 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chrX_+_94234594 0.237 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr1_-_172206775 0.235 ENSMUST00000013842.5
ENSMUST00000111247.1
Pea15a

phosphoprotein enriched in astrocytes 15A

chr10_+_81176631 0.231 ENSMUST00000047864.9
Eef2
eukaryotic translation elongation factor 2
chrX_+_94234921 0.228 ENSMUST00000113908.1
ENSMUST00000113916.3
Klhl15

kelch-like 15

chr6_+_147091379 0.218 ENSMUST00000036003.7
Klhl42
kelch-like 42
chr19_+_44333092 0.210 ENSMUST00000058856.8
Scd4
stearoyl-coenzyme A desaturase 4
chr6_-_34177048 0.196 ENSMUST00000019143.8
Slc35b4
solute carrier family 35, member B4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.8 10.7 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.9 6.4 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.8 5.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.8 6.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.8 3.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.7 3.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.7 2.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.7 3.4 GO:0015671 oxygen transport(GO:0015671)
0.6 2.8 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799)
0.5 2.6 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.4 2.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 5.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.4 1.3 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.4 1.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.4 3.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.4 1.6 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.4 0.7 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.4 1.1 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.3 1.7 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3 2.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 5.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 1.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.3 4.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.3 0.9 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.3 1.5 GO:0010359 regulation of anion channel activity(GO:0010359)
0.3 1.5 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.3 0.8 GO:0019401 alditol biosynthetic process(GO:0019401)
0.2 1.2 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.2 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 1.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 3.8 GO:0032060 bleb assembly(GO:0032060)
0.2 2.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 1.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 1.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.2 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.2 1.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 3.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 1.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 2.9 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 1.5 GO:0009404 toxin metabolic process(GO:0009404)
0.2 1.8 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 4.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 0.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.6 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 1.7 GO:0007614 short-term memory(GO:0007614)
0.1 3.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.3 GO:0071476 cellular hypotonic response(GO:0071476)
0.1 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.1 0.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.7 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 1.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.6 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 2.0 GO:0048678 response to axon injury(GO:0048678)
0.0 0.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.3 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.1 GO:0001706 endoderm formation(GO:0001706)
0.0 1.0 GO:0006721 terpenoid metabolic process(GO:0006721)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.1 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 2.1 GO:0007613 memory(GO:0007613)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 2.5 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0 0.5 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 2.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.5 10.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.9 2.8 GO:0043512 inhibin A complex(GO:0043512)
0.4 1.1 GO:0005927 muscle tendon junction(GO:0005927)
0.4 1.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 1.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 1.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 2.1 GO:0097449 astrocyte projection(GO:0097449)
0.1 8.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.4 GO:0043203 axon hillock(GO:0043203)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.5 GO:0031512 motile primary cilium(GO:0031512)
0.1 4.1 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.3 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 6.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 3.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.5 GO:0005871 kinesin complex(GO:0005871)
0.0 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.6 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 2.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 3.7 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.9 GO:0030017 sarcomere(GO:0030017)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.1 6.4 GO:0015265 urea channel activity(GO:0015265)
0.9 3.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.8 3.4 GO:0004096 catalase activity(GO:0004096)
0.7 2.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 2.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 10.7 GO:0051787 misfolded protein binding(GO:0051787)
0.4 2.6 GO:0005042 netrin receptor activity(GO:0005042)
0.4 2.1 GO:0033691 sialic acid binding(GO:0033691)
0.4 1.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 5.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 1.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 2.0 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.3 2.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 0.9 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.3 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 3.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 0.8 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.2 0.7 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 2.8 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 0.8 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.2 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.7 GO:2001069 glycogen binding(GO:2001069)
0.2 3.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.2 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.1 0.6 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 1.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 3.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 4.0 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 2.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 2.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.2 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.8 GO:0020037 heme binding(GO:0020037)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)