Motif ID: Twist1

Z-value: 1.118


Transcription factors associated with Twist1:

Gene SymbolEntrez IDGene Name
Twist1 ENSMUSG00000035799.5 Twist1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Twist1mm10_v2_chr12_+_33957645_33957671-0.348.7e-02Click!


Activity profile for motif Twist1.

activity profile for motif Twist1


Sorted Z-values histogram for motif Twist1

Sorted Z-values for motif Twist1



Network of associatons between targets according to the STRING database.



First level regulatory network of Twist1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_119053339 6.016 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr2_-_172940299 5.095 ENSMUST00000009143.7
 Bmp7
bone morphogenetic protein 7
chr9_+_60794468 4.199 ENSMUST00000050183.6
 Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_-_95718800 4.159 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr19_+_25610533 3.918 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr7_+_45216671 2.976 ENSMUST00000134420.1
 Tead2
TEA domain family member 2
chr9_-_114844090 2.912 ENSMUST00000047013.3
 Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chrX_+_71050160 2.694 ENSMUST00000082088.3
ENSMUST00000114629.3
 Mamld1

mastermind-like domain containing 1

chr7_-_75308373 2.622 ENSMUST00000085164.5
 Sv2b
synaptic vesicle glycoprotein 2 b
chr16_-_18811615 2.557 ENSMUST00000096990.3
 Cdc45
cell division cycle 45
chr11_-_59290746 2.409 ENSMUST00000010044.7
 Wnt3a
wingless-related MMTV integration site 3A
chr9_+_65265173 2.394 ENSMUST00000048762.1
 Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr5_+_105519388 2.301 ENSMUST00000067924.6
ENSMUST00000150981.1
 Lrrc8c

leucine rich repeat containing 8 family, member C

chr2_-_180225812 2.247 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr6_-_124813065 2.111 ENSMUST00000149610.2
 Tpi1
triosephosphate isomerase 1
chr7_+_4119556 2.110 ENSMUST00000079415.5
 Ttyh1
tweety homolog 1 (Drosophila)
chr7_-_127218390 2.035 ENSMUST00000142356.1
ENSMUST00000106314.1
 Sept1

septin 1

chr7_+_4119525 1.975 ENSMUST00000119661.1
ENSMUST00000129423.1
 Ttyh1

tweety homolog 1 (Drosophila)

chr2_-_137116624 1.958 ENSMUST00000028735.7
 Jag1
jagged 1
chr9_-_44342332 1.954 ENSMUST00000097558.3
 Hmbs
hydroxymethylbilane synthase
chr6_+_85187438 1.903 ENSMUST00000045942.8
 Emx1
empty spiracles homeobox 1
chr18_-_67724560 1.868 ENSMUST00000120934.1
ENSMUST00000025420.7
ENSMUST00000122412.1
 Ptpn2


protein tyrosine phosphatase, non-receptor type 2


chr10_-_127030813 1.819 ENSMUST00000040560.4
 Tsfm
Ts translation elongation factor, mitochondrial
chr4_-_129558355 1.794 ENSMUST00000167288.1
ENSMUST00000134336.1
 Lck

lymphocyte protein tyrosine kinase

chr7_-_127218303 1.786 ENSMUST00000106313.1
 Sept1
septin 1
chrX_-_104671048 1.759 ENSMUST00000042070.5
 Zdhhc15
zinc finger, DHHC domain containing 15
chr4_-_129558387 1.757 ENSMUST00000067240.4
 Lck
lymphocyte protein tyrosine kinase
chr9_-_54661870 1.749 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr1_+_74791516 1.737 ENSMUST00000006718.8
 Wnt10a
wingless related MMTV integration site 10a
chr10_-_127030789 1.654 ENSMUST00000120547.1
ENSMUST00000152054.1
 Tsfm

Ts translation elongation factor, mitochondrial

chr9_+_118478851 1.620 ENSMUST00000150633.1
 Eomes
eomesodermin homolog (Xenopus laevis)
chr11_-_119355484 1.550 ENSMUST00000100172.2
ENSMUST00000005173.4
 Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr8_+_105305572 1.503 ENSMUST00000109375.2
 Elmo3
engulfment and cell motility 3
chr14_-_62761112 1.492 ENSMUST00000053959.6
 Ints6
integrator complex subunit 6
chr6_+_83135812 1.479 ENSMUST00000065512.4
 Rtkn
rhotekin
chr8_+_72135247 1.476 ENSMUST00000003575.9
 Tpm4
tropomyosin 4
chr2_-_33942111 1.434 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
 Gm13403


predicted gene 13403


chr9_+_55150050 1.407 ENSMUST00000122441.1
 Ube2q2
ubiquitin-conjugating enzyme E2Q (putative) 2
chr19_-_3686549 1.405 ENSMUST00000025856.10
ENSMUST00000176867.1
 Lrp5

low density lipoprotein receptor-related protein 5

chr13_-_98891036 1.360 ENSMUST00000109399.2
 Tnpo1
transportin 1
chr9_-_54661666 1.303 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr7_+_122289297 1.257 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr2_-_142901506 1.257 ENSMUST00000043589.7
 Kif16b
kinesin family member 16B
chr6_-_134566913 1.212 ENSMUST00000032322.8
 Lrp6
low density lipoprotein receptor-related protein 6
chr13_-_98890974 1.180 ENSMUST00000179301.1
ENSMUST00000179271.1
 Tnpo1

transportin 1

chr11_+_69935796 1.158 ENSMUST00000018698.5
 Ybx2
Y box protein 2
chr7_+_127800844 1.152 ENSMUST00000106271.1
ENSMUST00000138432.1
 Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr11_+_69935894 1.124 ENSMUST00000149194.1
 Ybx2
Y box protein 2
chr5_+_149411749 1.063 ENSMUST00000093110.5
 Medag
mesenteric estrogen dependent adipogenesis
chr11_+_53770458 1.060 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
 Irf1



interferon regulatory factor 1



chr17_+_34039437 1.058 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
 Col11a2



collagen, type XI, alpha 2



chr7_+_82867327 1.051 ENSMUST00000082237.5
 Mex3b
mex3 homolog B (C. elegans)
chr6_-_29165003 0.990 ENSMUST00000007993.9
 Rbm28
RNA binding motif protein 28
chr4_-_11386757 0.974 ENSMUST00000108313.1
ENSMUST00000108311.2
 Esrp1

epithelial splicing regulatory protein 1

chr4_-_57143437 0.964 ENSMUST00000095076.3
ENSMUST00000030142.3
 Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chrX_-_18461371 0.950 ENSMUST00000044188.4
 4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr8_+_13757663 0.938 ENSMUST00000043962.8
 Cdc16
CDC16 cell division cycle 16
chrX_+_100730178 0.931 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr11_-_68927049 0.910 ENSMUST00000038932.7
 Odf4
outer dense fiber of sperm tails 4
chr1_-_172590463 0.882 ENSMUST00000065679.6
 Slamf8
SLAM family member 8
chr10_-_127341583 0.862 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr7_-_29232478 0.784 ENSMUST00000085818.4
 Kcnk6
potassium inwardly-rectifying channel, subfamily K, member 6
chr16_+_78930940 0.776 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr8_-_126475062 0.747 ENSMUST00000170518.1
 Gm17296
predicted gene, 17296
chr15_+_100227819 0.735 ENSMUST00000023769.4
 Atf1
activating transcription factor 1
chr11_+_76179658 0.689 ENSMUST00000129853.1
ENSMUST00000179223.1
 Fam57a
Fam57a
family with sequence similarity 57, member A
family with sequence similarity 57, member A
chr13_+_55209776 0.684 ENSMUST00000099490.2
 Nsd1
nuclear receptor-binding SET-domain protein 1
chr1_+_171437535 0.674 ENSMUST00000043839.4
 F11r
F11 receptor
chr16_+_37776873 0.633 ENSMUST00000114763.2
 Fstl1
follistatin-like 1
chr11_+_58009064 0.598 ENSMUST00000071487.6
ENSMUST00000178636.1
 Larp1

La ribonucleoprotein domain family, member 1

chr13_+_73626886 0.524 ENSMUST00000022104.7
 Tert
telomerase reverse transcriptase
chr11_-_102406783 0.519 ENSMUST00000155104.1
ENSMUST00000130436.1
 Slc25a39

solute carrier family 25, member 39

chr7_-_133123770 0.517 ENSMUST00000164896.1
ENSMUST00000171968.1
 Ctbp2

C-terminal binding protein 2

chr18_+_60911757 0.514 ENSMUST00000040359.5
 Arsi
arylsulfatase i
chr2_-_26122769 0.495 ENSMUST00000140993.1
ENSMUST00000028300.5
 Nacc2

nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

chr15_+_100227871 0.488 ENSMUST00000163855.1
 Atf1
activating transcription factor 1
chr19_-_24280551 0.486 ENSMUST00000081333.4
 Fxn
frataxin
chr17_+_3114957 0.486 ENSMUST00000076734.6
 Scaf8
SR-related CTD-associated factor 8
chr10_+_61175206 0.476 ENSMUST00000079235.5
 Tbata
thymus, brain and testes associated
chr7_+_27486910 0.456 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chr12_-_51829525 0.447 ENSMUST00000179265.1
ENSMUST00000042052.8
 Hectd1

HECT domain containing 1

chr3_+_90051630 0.442 ENSMUST00000159064.1
 4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr10_-_75517324 0.441 ENSMUST00000039796.7
 Gucd1
guanylyl cyclase domain containing 1
chr4_-_130275523 0.436 ENSMUST00000146478.1
 Serinc2
serine incorporator 2
chr11_-_72207413 0.428 ENSMUST00000108505.1
 4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr16_+_62814676 0.406 ENSMUST00000055557.5
 Stx19
syntaxin 19
chr11_+_97663366 0.395 ENSMUST00000044730.5
 Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr9_+_111118070 0.356 ENSMUST00000035078.6
ENSMUST00000098340.2
 Lrrfip2

leucine rich repeat (in FLII) interacting protein 2

chr4_-_130275542 0.327 ENSMUST00000154846.1
ENSMUST00000105996.1
 Serinc2

serine incorporator 2

chr11_+_72207537 0.324 ENSMUST00000021158.3
 Txndc17
thioredoxin domain containing 17
chr11_-_94549165 0.323 ENSMUST00000040487.3
 Rsad1
radical S-adenosyl methionine domain containing 1
chr9_-_109082372 0.313 ENSMUST00000167504.1
 Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr15_+_100304782 0.311 ENSMUST00000067752.3
 Mettl7a1
methyltransferase like 7A1
chr18_+_77065195 0.292 ENSMUST00000114777.2
 Pias2
protein inhibitor of activated STAT 2
chr6_+_29398920 0.233 ENSMUST00000181464.1
ENSMUST00000180829.1
 Ccdc136

coiled-coil domain containing 136

chr18_-_16809233 0.231 ENSMUST00000025166.7
 Cdh2
cadherin 2
chr6_-_90716489 0.187 ENSMUST00000101153.3
 Iqsec1
IQ motif and Sec7 domain 1
chr17_-_12992487 0.185 ENSMUST00000159551.1
ENSMUST00000160781.1
 Wtap

Wilms' tumour 1-associating protein

chr11_+_102189620 0.185 ENSMUST00000070334.3
ENSMUST00000078975.7
 G6pc3

glucose 6 phosphatase, catalytic, 3

chr7_-_70360593 0.165 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_-_39190687 0.127 ENSMUST00000142872.1
ENSMUST00000038874.5
 Scai

suppressor of cancer cell invasion

chrX_-_166585679 0.105 ENSMUST00000000412.2
 Egfl6
EGF-like-domain, multiple 6
chr12_+_112146187 0.102 ENSMUST00000128402.2
 Kif26a
kinesin family member 26A
chr16_-_20426375 0.083 ENSMUST00000079158.6
 Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_+_174110340 0.073 ENSMUST00000044415.9
 Npepl1
aminopeptidase-like 1
chr10_+_14523062 0.061 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr2_-_32784424 0.055 ENSMUST00000102813.1
 1700019L03Rik
RIKEN cDNA 1700019L03 gene
chr13_+_67863324 0.052 ENSMUST00000078471.5
 BC048507
cDNA sequence BC048507
chr8_+_119910792 0.028 ENSMUST00000108988.2
ENSMUST00000108982.4
ENSMUST00000127664.1
 Usp10

Gm20388
ubiquitin specific peptidase 10

predicted gene 20388
chr17_+_45563928 0.018 ENSMUST00000041353.6
 Slc35b2
solute carrier family 35, member B2
chr8_-_64693027 0.015 ENSMUST00000048967.7
 Cpe
carboxypeptidase E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0060032 notochord regression(GO:0060032)
1.7 5.1 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.0 3.8 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
0.9 2.6 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.8 2.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) negative regulation of dopaminergic neuron differentiation(GO:1904339) regulation of cardiac cell fate specification(GO:2000043)
0.7 2.1 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.7 3.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.6 5.7 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.6 1.9 GO:0038145 interleukin-4-mediated signaling pathway(GO:0035771) macrophage colony-stimulating factor signaling pathway(GO:0038145) tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.6 1.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.5 1.6 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.5 1.4 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.5 4.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.4 3.6 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.4 2.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 2.0 GO:0072015 ciliary body morphogenesis(GO:0061073) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.4 1.1 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.4 1.1 GO:0060023 soft palate development(GO:0060023)
0.3 0.9 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.3 1.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 4.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 2.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 2.0 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 2.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 3.0 GO:0030903 notochord development(GO:0030903)
0.2 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.2 0.8 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.8 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 0.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.5 GO:0019230 proprioception(GO:0019230)
0.1 3.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.9 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.4 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 3.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.5 GO:0016180 snRNA processing(GO:0016180)
0.1 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 2.3 GO:0048255 mRNA stabilization(GO:0048255)
0.1 2.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 1.6 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.2 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 2.5 GO:0045444 fat cell differentiation(GO:0045444)
0.0 1.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.6 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.5 GO:0006909 phagocytosis(GO:0006909)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.2 3.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.0 4.2 GO:0043293 apoptosome(GO:0043293)
0.9 2.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 4.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.6 2.2 GO:0043259 laminin-10 complex(GO:0043259)
0.5 6.9 GO:0097542 ciliary tip(GO:0097542)
0.4 3.8 GO:0072687 meiotic spindle(GO:0072687)
0.3 1.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 3.6 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.5 GO:0032039 integrator complex(GO:0032039)
0.1 1.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0031201 SNARE complex(GO:0031201)
0.1 1.5 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.3 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 5.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.2 GO:0034399 nuclear periphery(GO:0034399)
0.0 2.0 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.8 2.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.7 3.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 5.1 GO:0070700 BMP receptor binding(GO:0070700)
0.5 3.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 4.2 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.3 2.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 2.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 1.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 2.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.6 GO:0000339 RNA cap binding(GO:0000339) translation activator activity(GO:0008494)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 2.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 2.0 GO:0005112 Notch binding(GO:0005112)
0.1 2.0 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 11.5 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 3.8 GO:0005525 GTP binding(GO:0005525)