Motif ID: Wrnip1_Mta3_Rcor1

Z-value: 4.477

Transcription factors associated with Wrnip1_Mta3_Rcor1:

Gene SymbolEntrez IDGene Name
Mta3 ENSMUSG00000055817.11 Mta3
Rcor1 ENSMUSG00000037896.11 Rcor1
Wrnip1 ENSMUSG00000021400.6 Wrnip1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rcor1mm10_v2_chr12_+_111039334_111039400-0.807.1e-07Click!
Mta3mm10_v2_chr17_+_83706170_837062000.394.8e-02Click!
Wrnip1mm10_v2_chr13_+_32802007_328021520.376.6e-02Click!


Activity profile for motif Wrnip1_Mta3_Rcor1.

activity profile for motif Wrnip1_Mta3_Rcor1


Sorted Z-values histogram for motif Wrnip1_Mta3_Rcor1

Sorted Z-values for motif Wrnip1_Mta3_Rcor1



Network of associatons between targets according to the STRING database.



First level regulatory network of Wrnip1_Mta3_Rcor1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_120202104 20.857 ENSMUST00000033198.5
 Crym
crystallin, mu
chr2_+_180499893 15.940 ENSMUST00000029084.2
 Ntsr1
neurotensin receptor 1
chr7_+_45699843 14.774 ENSMUST00000003360.7
 Car11
carbonic anhydrase 11
chrX_+_73483602 14.686 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr5_-_108549934 14.068 ENSMUST00000129040.1
ENSMUST00000046892.9
 Cplx1

complexin 1

chr2_+_90885860 13.729 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr14_-_29721835 12.796 ENSMUST00000022567.7
 Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr7_-_142657466 12.327 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr4_-_129121889 12.017 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
 Hpca


hippocalcin


chr13_-_71963713 11.768 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr10_+_127078886 11.595 ENSMUST00000039259.6
 Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_-_181156993 11.516 ENSMUST00000055990.7
 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr11_+_104132841 10.908 ENSMUST00000093925.4
 Crhr1
corticotropin releasing hormone receptor 1
chr7_+_44428938 10.815 ENSMUST00000127790.1
 Lrrc4b
leucine rich repeat containing 4B
chr3_-_66981279 10.780 ENSMUST00000162098.2
 Shox2
short stature homeobox 2
chr9_+_109931774 10.753 ENSMUST00000169851.2
 Map4
microtubule-associated protein 4
chr14_-_55116935 10.620 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr19_-_42431778 10.606 ENSMUST00000048630.6
 Crtac1
cartilage acidic protein 1
chr10_-_81025521 10.588 ENSMUST00000144640.1
 Diras1
DIRAS family, GTP-binding RAS-like 1
chr19_+_6418731 10.474 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
 Nrxn2


neurexin II



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,310 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 75.3 GO:0035640 exploration behavior(GO:0035640)
1.0 67.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.6 48.9 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
1.6 42.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
1.5 40.7 GO:0007616 long-term memory(GO:0007616)
1.0 38.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.8 38.3 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.0 36.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.6 36.2 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
2.3 36.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
4.7 32.7 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
3.3 30.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.3 30.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
1.3 29.3 GO:0048268 clathrin coat assembly(GO:0048268)
3.2 29.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
9.5 28.4 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.5 27.6 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
3.4 27.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.6 27.0 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
1.5 27.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 383 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 629.1 GO:0016021 integral component of membrane(GO:0016021)
1.0 189.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 180.8 GO:0043005 neuron projection(GO:0043005)
1.1 174.8 GO:0070382 exocytic vesicle(GO:0070382)
1.7 115.0 GO:0042734 presynaptic membrane(GO:0042734)
2.1 87.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.8 76.9 GO:0055037 recycling endosome(GO:0055037)
1.7 70.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.3 70.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.6 69.3 GO:0031225 anchored component of membrane(GO:0031225)
0.3 61.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 61.5 GO:0005615 extracellular space(GO:0005615)
0.4 56.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.1 53.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
2.0 53.0 GO:0033268 node of Ranvier(GO:0033268)
0.8 47.0 GO:0005581 collagen trimer(GO:0005581)
1.7 42.3 GO:0071565 nBAF complex(GO:0071565)
4.2 41.8 GO:0044327 dendritic spine head(GO:0044327)
0.9 41.6 GO:0043195 terminal bouton(GO:0043195)
0.6 39.1 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 701 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 87.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 82.4 GO:0005509 calcium ion binding(GO:0005509)
0.9 52.1 GO:0030507 spectrin binding(GO:0030507)
2.2 49.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
1.8 45.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.8 43.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 43.2 GO:0019210 kinase inhibitor activity(GO:0019210)
1.1 41.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.8 41.0 GO:0035254 glutamate receptor binding(GO:0035254)
0.9 40.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 38.7 GO:0017124 SH3 domain binding(GO:0017124)
0.8 38.3 GO:0030276 clathrin binding(GO:0030276)
1.0 37.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.6 36.1 GO:0016247 channel regulator activity(GO:0016247)
2.4 35.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.9 34.5 GO:0005246 calcium channel regulator activity(GO:0005246)
1.7 33.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.0 32.7 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
1.8 32.5 GO:0004890 GABA-A receptor activity(GO:0004890)
1.4 32.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)