Motif ID: Xbp1_Creb3l1

Z-value: 0.562

Transcription factors associated with Xbp1_Creb3l1:

Gene SymbolEntrez IDGene Name
Creb3l1 ENSMUSG00000027230.9 Creb3l1
Xbp1 ENSMUSG00000020484.12 Xbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l1mm10_v2_chr2_-_92024502_920245290.271.9e-01Click!
Xbp1mm10_v2_chr11_+_5520652_55206590.086.8e-01Click!


Activity profile for motif Xbp1_Creb3l1.

activity profile for motif Xbp1_Creb3l1


Sorted Z-values histogram for motif Xbp1_Creb3l1

Sorted Z-values for motif Xbp1_Creb3l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Top targets:


Showing 1 to 20 of 186 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_45092130 1.451 ENSMUST00000148175.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45092198 1.049 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
 Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr15_+_79516396 0.815 ENSMUST00000010974.7
 Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr6_-_101377342 0.774 ENSMUST00000151175.1
 Pdzrn3
PDZ domain containing RING finger 3
chr3_+_93520473 0.750 ENSMUST00000029515.4
 S100a11
S100 calcium binding protein A11 (calgizzarin)
chr7_-_45091713 0.709 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr6_+_29348069 0.590 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
 Calu


calumenin


chr10_+_91082940 0.542 ENSMUST00000020150.3
 Ikbip
IKBKB interacting protein
chr3_-_27710413 0.521 ENSMUST00000046157.4
 Fndc3b
fibronectin type III domain containing 3B
chr11_-_108343917 0.504 ENSMUST00000059595.4
 Prkca
protein kinase C, alpha
chr3_+_96697076 0.475 ENSMUST00000162778.2
ENSMUST00000064900.9
 Pias3

protein inhibitor of activated STAT 3

chr5_-_35679416 0.457 ENSMUST00000114233.2
 Htra3
HtrA serine peptidase 3
chr10_+_91083036 0.442 ENSMUST00000020149.5
 Ikbip
IKBKB interacting protein
chr1_-_55226768 0.439 ENSMUST00000027121.8
ENSMUST00000114428.2
 Rftn2

raftlin family member 2

chr3_+_96697100 0.421 ENSMUST00000107077.3
 Pias3
protein inhibitor of activated STAT 3
chr5_+_64970069 0.419 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr4_-_108406676 0.415 ENSMUST00000184609.1
 Gpx7
glutathione peroxidase 7
chr4_-_155653184 0.371 ENSMUST00000030937.1
 Mmp23
matrix metallopeptidase 23
chr7_-_142578093 0.364 ENSMUST00000149974.1
ENSMUST00000152754.1
 H19

H19 fetal liver mRNA

chr3_-_97767916 0.364 ENSMUST00000045243.8
 Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.5 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.1 0.3 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.1 0.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)