Motif ID: Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 7.364

Transcription factors associated with Ybx1_Nfya_Nfyb_Nfyc_Cebpz:

Gene SymbolEntrez IDGene Name
Cebpz ENSMUSG00000024081.8 Cebpz
Nfya ENSMUSG00000023994.7 Nfya
Nfyb ENSMUSG00000020248.12 Nfyb
Nfyc ENSMUSG00000032897.11 Nfyc
Ybx1 ENSMUSG00000028639.8 Ybx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ybx1mm10_v2_chr4_-_119294520_1192946040.822.3e-07Click!
Nfyamm10_v2_chr17_-_48409729_48409906-0.653.6e-04Click!
Nfybmm10_v2_chr10_-_82764088_82764144-0.395.1e-02Click!
Nfycmm10_v2_chr4_-_120825665_120825707-0.349.4e-02Click!
Cebpzmm10_v2_chr17_-_78937031_789370740.281.6e-01Click!


Activity profile for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz.

activity profile for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz


Sorted Z-values histogram for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Sorted Z-values for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz



Network of associatons between targets according to the STRING database.



First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_83955507 43.090 ENSMUST00000005607.8
 Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr11_-_99024179 34.716 ENSMUST00000068031.7
 Top2a
topoisomerase (DNA) II alpha
chr6_+_124829582 33.208 ENSMUST00000024270.7
 Cdca3
cell division cycle associated 3
chr16_-_17125106 30.445 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr3_-_27153844 29.368 ENSMUST00000176242.2
ENSMUST00000176780.1
 Ect2

ect2 oncogene

chr3_-_27153861 29.109 ENSMUST00000108300.1
ENSMUST00000108298.2
 Ect2

ect2 oncogene

chr3_-_27153782 28.719 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
 Ect2


ect2 oncogene


chr11_-_87108656 27.821 ENSMUST00000051395.8
 Prr11
proline rich 11
chr8_+_57511833 25.116 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr7_-_48881596 24.870 ENSMUST00000119223.1
 E2f8
E2F transcription factor 8
chr1_+_139454747 23.552 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr14_-_67715585 23.244 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chr4_-_41464816 22.743 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
 Kif24


kinesin family member 24


chr17_-_24251382 22.152 ENSMUST00000115390.3
 Ccnf
cyclin F
chr6_+_124829540 21.505 ENSMUST00000150120.1
 Cdca3
cell division cycle associated 3
chr3_-_89418287 21.427 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr14_+_67716095 20.522 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
 Kctd9


potassium channel tetramerisation domain containing 9


chr6_+_124830217 20.470 ENSMUST00000131847.1
ENSMUST00000151674.1
 Cdca3

cell division cycle associated 3

chr14_+_46760526 19.332 ENSMUST00000067426.4
 Cdkn3
cyclin-dependent kinase inhibitor 3
chr6_-_82774448 18.960 ENSMUST00000000642.4
 Hk2
hexokinase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 638 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 108.0 GO:0007067 mitotic nuclear division(GO:0007067)
5.9 100.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.7 99.7 GO:0007059 chromosome segregation(GO:0007059)
6.6 79.6 GO:0007100 mitotic centrosome separation(GO:0007100)
2.3 71.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
2.2 62.9 GO:0006270 DNA replication initiation(GO:0006270)
1.1 49.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
3.2 47.3 GO:0030953 astral microtubule organization(GO:0030953)
2.2 46.9 GO:0051310 metaphase plate congression(GO:0051310)
14.7 44.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
6.8 40.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
2.4 38.9 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
2.8 36.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
8.7 34.7 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
1.6 34.5 GO:0006298 mismatch repair(GO:0006298)
2.6 34.1 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
2.4 31.4 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
3.4 30.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
4.2 29.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
3.7 29.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 254 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 208.4 GO:0005654 nucleoplasm(GO:0005654)
0.0 179.3 GO:0005634 nucleus(GO:0005634)
1.2 114.7 GO:0005814 centriole(GO:0005814)
0.3 111.0 GO:0005667 transcription factor complex(GO:0005667)
19.1 95.3 GO:0097149 centralspindlin complex(GO:0097149)
1.0 94.2 GO:0000776 kinetochore(GO:0000776)
4.1 53.7 GO:0031616 spindle pole centrosome(GO:0031616)
1.2 51.1 GO:0005657 replication fork(GO:0005657)
1.1 46.2 GO:0005876 spindle microtubule(GO:0005876)
8.5 42.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.6 41.5 GO:0005643 nuclear pore(GO:0005643)
0.4 39.0 GO:0016605 PML body(GO:0016605)
2.4 35.7 GO:0042555 MCM complex(GO:0042555)
2.7 35.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
8.7 34.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
4.2 33.8 GO:0005818 aster(GO:0005818)
3.8 33.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.8 33.7 GO:0010369 chromocenter(GO:0010369)
0.7 30.4 GO:0005871 kinesin complex(GO:0005871)
2.1 27.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 403 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 91.7 GO:0001047 core promoter binding(GO:0001047)
0.8 91.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5 83.7 GO:0042393 histone binding(GO:0042393)
0.9 74.3 GO:0003697 single-stranded DNA binding(GO:0003697)
1.0 70.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 66.7 GO:0008017 microtubule binding(GO:0008017)
0.4 56.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.1 54.7 GO:0003777 microtubule motor activity(GO:0003777)
1.7 50.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.7 46.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 45.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.3 41.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 40.8 GO:0003682 chromatin binding(GO:0003682)
0.9 38.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
2.0 37.5 GO:0035173 histone kinase activity(GO:0035173)
5.9 35.6 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
4.2 33.4 GO:0003688 DNA replication origin binding(GO:0003688)
10.5 31.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
1.1 30.8 GO:0050681 androgen receptor binding(GO:0050681)
0.7 29.9 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)