Motif ID: Zbtb12

Z-value: 0.617


Transcription factors associated with Zbtb12:

Gene SymbolEntrez IDGene Name
Zbtb12 ENSMUSG00000049823.8 Zbtb12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_34894573-0.038.9e-01Click!


Activity profile for motif Zbtb12.

activity profile for motif Zbtb12


Sorted Z-values histogram for motif Zbtb12

Sorted Z-values for motif Zbtb12



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_12027958 2.757 ENSMUST00000109654.1
Grb10
growth factor receptor bound protein 10
chr6_-_124814288 2.659 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr17_-_15375969 2.275 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr19_+_59260878 2.220 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr18_-_70472429 1.886 ENSMUST00000067556.3
4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr13_+_104229366 1.836 ENSMUST00000022227.6
Cenpk
centromere protein K
chr3_+_88081997 1.586 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr3_-_84155762 1.425 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr11_-_88718078 1.167 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr14_-_103844173 1.150 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr4_+_32983417 1.118 ENSMUST00000084747.5
Rragd
Ras-related GTP binding D
chr17_-_27029009 1.113 ENSMUST00000078691.5
Bak1
BCL2-antagonist/killer 1
chr17_+_17831004 1.093 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr1_+_37997975 1.032 ENSMUST00000027252.7
Eif5b
eukaryotic translation initiation factor 5B
chr5_+_92603039 1.007 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr4_-_151057933 1.002 ENSMUST00000030797.3
Vamp3
vesicle-associated membrane protein 3
chr3_+_5218546 0.992 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr2_-_28916668 0.990 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr11_+_54902743 0.949 ENSMUST00000082430.3
Gpx3
glutathione peroxidase 3
chr3_+_5218516 0.944 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr14_+_79481164 0.925 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr8_-_45382198 0.912 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr9_+_57827284 0.823 ENSMUST00000163186.1
Gm17231
predicted gene 17231
chr3_+_5218589 0.803 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr19_-_10240689 0.785 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr11_+_54902917 0.724 ENSMUST00000149324.1
Gpx3
glutathione peroxidase 3
chr7_+_92875253 0.669 ENSMUST00000076052.6
Prcp
prolylcarboxypeptidase (angiotensinase C)
chr6_+_37900477 0.661 ENSMUST00000120238.1
Trim24
tripartite motif-containing 24
chr1_+_69826986 0.660 ENSMUST00000065425.5
ENSMUST00000113940.2
Spag16

sperm associated antigen 16

chr13_+_76098734 0.649 ENSMUST00000091466.3
Ttc37
tetratricopeptide repeat domain 37
chr14_-_79481268 0.585 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr2_+_31759932 0.558 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr9_+_22411515 0.501 ENSMUST00000058868.7
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr16_-_33967032 0.500 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr10_-_86011833 0.451 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr3_-_131344892 0.379 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2

sphingomyelin synthase 2

chr2_+_31759993 0.367 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr17_-_56874421 0.347 ENSMUST00000043062.4
Acsbg2
acyl-CoA synthetase bubblegum family member 2
chr6_+_108065035 0.306 ENSMUST00000049246.6
Setmar
SET domain without mariner transposase fusion
chr17_-_32189457 0.302 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3

epoxide hydrolase 3

chr15_-_88954400 0.300 ENSMUST00000109371.1
Ttll8
tubulin tyrosine ligase-like family, member 8
chr12_+_105784694 0.285 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola





poly (A) polymerase alpha





chr12_-_101958148 0.277 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr9_-_78481724 0.246 ENSMUST00000042235.8
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr5_+_67260696 0.234 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33

transmembrane protein 33

chr17_+_83350925 0.210 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
Eml4


echinoderm microtubule associated protein like 4


chr17_-_27909206 0.197 ENSMUST00000114848.1
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_+_98446826 0.189 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr17_+_27029259 0.177 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr7_-_127993831 0.168 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chr7_-_25477607 0.147 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr4_-_119173849 0.140 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr15_+_82341179 0.140 ENSMUST00000050349.2
Fam109b
family with sequence similarity 109, member B
chrX_-_140956675 0.127 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr6_-_33060172 0.118 ENSMUST00000115091.1
ENSMUST00000127666.1
Chchd3

coiled-coil-helix-coiled-coil-helix domain containing 3

chr11_-_100441795 0.065 ENSMUST00000107398.1
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr14_+_34220028 0.049 ENSMUST00000119693.1
ENSMUST00000035351.5
Syt15

synaptotagmin XV

chr8_-_69774884 0.046 ENSMUST00000137573.1
ENSMUST00000149782.1
Zfp866
Gm20422
zinc finger protein 866
predicted gene 20422
chr15_-_79546741 0.017 ENSMUST00000054014.7
Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr19_+_46573362 0.014 ENSMUST00000026011.6
Sfxn2
sideroflexin 2
chr5_+_30281377 0.003 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.8 2.3 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.4 1.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.4 1.1 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.4 2.2 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 0.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.3 2.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 0.5 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.7 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 1.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.0 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 1.0 GO:0030901 midbrain development(GO:0030901)
0.0 1.0 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.6 GO:0055087 Ski complex(GO:0055087)
0.1 2.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.1 GO:0046930 pore complex(GO:0046930)
0.0 0.7 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 1.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.4 1.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.6 GO:0032027 myosin light chain binding(GO:0032027)
0.3 1.0 GO:2001069 glycogen binding(GO:2001069)
0.2 2.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 2.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 2.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)