Motif ID: Zbtb14

Z-value: 2.109


Transcription factors associated with Zbtb14:

Gene SymbolEntrez IDGene Name
Zbtb14 ENSMUSG00000049672.8 Zbtb14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb14mm10_v2_chr17_+_69383319_69383394-0.601.3e-03Click!


Activity profile for motif Zbtb14.

activity profile for motif Zbtb14


Sorted Z-values histogram for motif Zbtb14

Sorted Z-values for motif Zbtb14



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_6065737 10.666 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr11_+_104231573 10.436 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr11_-_6065538 9.969 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr11_+_104231390 9.703 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr11_-_7213897 9.331 ENSMUST00000020702.4
ENSMUST00000135887.2
Igfbp3

insulin-like growth factor binding protein 3

chr11_+_104231515 8.973 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr11_+_104231465 8.815 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr7_-_27396542 8.154 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr10_+_13966268 7.861 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_130936172 7.814 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr6_-_32588192 7.764 ENSMUST00000115096.2
Plxna4
plexin A4
chr7_-_63212514 7.724 ENSMUST00000032738.5
Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
chr10_+_58813359 7.651 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr11_-_102296618 7.343 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr5_-_115194283 7.219 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr15_+_83779975 7.139 ENSMUST00000163723.1
Mpped1
metallophosphoesterase domain containing 1
chr8_-_115706994 7.089 ENSMUST00000069009.6
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr15_+_83779999 6.939 ENSMUST00000046168.5
Mpped1
metallophosphoesterase domain containing 1
chr2_-_104410334 6.778 ENSMUST00000089726.3
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr1_-_132741750 6.523 ENSMUST00000094569.4
ENSMUST00000163770.1
Nfasc

neurofascin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 361 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 43.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
6.9 20.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
3.2 19.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 16.7 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.6 15.2 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.4 14.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
2.8 11.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.7 10.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.7 9.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.5 9.8 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
1.1 8.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.6 8.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
1.3 7.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.7 7.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
2.6 7.7 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.1 7.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.7 7.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 7.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 7.3 GO:0016578 histone deubiquitination(GO:0016578)
0.3 6.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 154 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.8 37.9 GO:0045298 tubulin complex(GO:0045298)
0.2 24.3 GO:0055037 recycling endosome(GO:0055037)
0.7 22.6 GO:0051233 spindle midzone(GO:0051233)
0.4 22.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 14.4 GO:0043204 perikaryon(GO:0043204)
2.2 13.2 GO:0008091 spectrin(GO:0008091)
0.1 12.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 11.8 GO:0031225 anchored component of membrane(GO:0031225)
0.4 10.2 GO:0033268 node of Ranvier(GO:0033268)
2.3 9.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.8 9.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 8.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 8.5 GO:0045202 synapse(GO:0045202)
0.2 8.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 8.1 GO:0030427 site of polarized growth(GO:0030427)
0.4 7.9 GO:0000421 autophagosome membrane(GO:0000421)
0.6 7.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 7.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.6 7.3 GO:0000124 SAGA complex(GO:0000124)
1.4 7.1 GO:0030314 junctional membrane complex(GO:0030314)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 237 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 33.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.9 21.4 GO:0043274 phospholipase binding(GO:0043274)
1.9 15.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.6 13.1 GO:0030506 ankyrin binding(GO:0030506)
0.6 12.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 10.7 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.2 10.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 9.4 GO:0005246 calcium channel regulator activity(GO:0005246)
1.9 9.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 9.3 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.6 9.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 9.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.5 8.9 GO:0042296 ISG15 transferase activity(GO:0042296)
1.5 8.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.8 8.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 8.7 GO:0031489 myosin V binding(GO:0031489)
0.5 8.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.9 7.7 GO:0015643 toxic substance binding(GO:0015643)
1.5 7.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 7.1 GO:0008013 beta-catenin binding(GO:0008013)