Motif ID: Zbtb4

Z-value: 0.625


Transcription factors associated with Zbtb4:

Gene SymbolEntrez IDGene Name
Zbtb4 ENSMUSG00000018750.8 Zbtb4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb4mm10_v2_chr11_+_69765970_697660270.116.1e-01Click!


Activity profile for motif Zbtb4.

activity profile for motif Zbtb4


Sorted Z-values histogram for motif Zbtb4

Sorted Z-values for motif Zbtb4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 2.984 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr4_+_141301228 2.265 ENSMUST00000006614.2
 Epha2
Eph receptor A2
chr5_+_139543889 1.929 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr2_-_9890026 1.890 ENSMUST00000130615.1
 Gata3
GATA binding protein 3
chr19_+_55742242 1.576 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
 Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr19_+_55742056 1.228 ENSMUST00000111659.2
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr9_-_106158109 1.074 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chrX_+_36195904 1.005 ENSMUST00000115258.2
 Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195968 1.002 ENSMUST00000115256.1
 Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195950 0.996 ENSMUST00000115257.1
 Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195938 0.994 ENSMUST00000048067.3
 Zcchc12
zinc finger, CCHC domain containing 12
chr5_+_147957310 0.789 ENSMUST00000085558.4
ENSMUST00000129092.1
 Mtus2

microtubule associated tumor suppressor candidate 2

chr2_-_170427828 0.655 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
 Bcas1


breast carcinoma amplified sequence 1


chr19_+_46707443 0.597 ENSMUST00000003655.7
 As3mt
arsenic (+3 oxidation state) methyltransferase
chr9_+_60794468 0.564 ENSMUST00000050183.6
 Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_-_70657121 0.541 ENSMUST00000049031.5
 Fam63b
family with sequence similarity 63, member B
chr19_+_41482632 0.533 ENSMUST00000067795.5
 Lcor
ligand dependent nuclear receptor corepressor
chr4_+_59805829 0.522 ENSMUST00000030080.6
 Snx30
sorting nexin family member 30
chr6_+_48841476 0.521 ENSMUST00000101426.4
 Tmem176a
transmembrane protein 176A
chr6_+_48841633 0.520 ENSMUST00000168406.1
 Tmem176a
transmembrane protein 176A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.0 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 2.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.8 2.3 GO:0014028 notochord formation(GO:0014028)
0.6 1.9 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.2 1.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 1.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.7 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 0.6 GO:0030070 insulin processing(GO:0030070)
0.1 0.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.2 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.5 GO:0009992 cellular water homeostasis(GO:0009992)
0.1 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.4 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 GO:0016607 nuclear speck(GO:0016607)
0.3 2.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.8 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0043293 apoptosome(GO:0043293)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.4 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0060091 kinocilium(GO:0060091)
0.1 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.0 GO:0032183 SUMO binding(GO:0032183)
0.1 2.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 2.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.4 1.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.1 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 0.7 GO:0042806 fucose binding(GO:0042806)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.0 0.7 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.2 0.5 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.5 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1 0.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.1 0.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.1 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)