Motif ID: Zbtb49

Z-value: 0.283


Transcription factors associated with Zbtb49:

Gene SymbolEntrez IDGene Name
Zbtb49 ENSMUSG00000029127.9 Zbtb49

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb49mm10_v2_chr5_-_38220400_382204590.517.6e-03Click!


Activity profile for motif Zbtb49.

activity profile for motif Zbtb49


Sorted Z-values histogram for motif Zbtb49

Sorted Z-values for motif Zbtb49



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb49

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_140154712 1.189 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr9_+_45430293 1.180 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr18_-_61911783 0.825 ENSMUST00000049378.8
ENSMUST00000166783.1
 Ablim3

actin binding LIM protein family, member 3

chr9_+_40269430 0.794 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr1_+_32172711 0.719 ENSMUST00000027226.5
 Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr9_+_40269273 0.717 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40269202 0.711 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta

chr15_-_102257449 0.686 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr15_-_102257306 0.572 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr7_+_4460687 0.363 ENSMUST00000167298.1
ENSMUST00000171445.1
 Eps8l1

EPS8-like 1

chr9_+_50856924 0.343 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
 Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chr5_-_108629712 0.268 ENSMUST00000046603.8
 Gak
cyclin G associated kinase
chr18_+_23753708 0.228 ENSMUST00000115830.1
 Mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_+_108629791 0.195 ENSMUST00000063272.6
 Tmem175
transmembrane protein 175
chr5_+_108629990 0.195 ENSMUST00000078323.6
ENSMUST00000120327.1
 Tmem175

transmembrane protein 175

chr3_-_53017195 0.112 ENSMUST00000036665.4
 Cog6
component of oligomeric golgi complex 6
chr8_+_4493443 0.110 ENSMUST00000175781.2
 Cers4
ceramide synthase 4
chr17_+_24736639 0.110 ENSMUST00000115262.1
 Msrb1
methionine sulfoxide reductase B1
chr16_-_70382385 0.067 ENSMUST00000072455.4
 4930423O20Rik
RIKEN cDNA 4930423O20 gene
chr17_+_24736673 0.053 ENSMUST00000101800.5
 Msrb1
methionine sulfoxide reductase B1
chr12_+_89812467 0.039 ENSMUST00000110133.2
ENSMUST00000110130.2
 Nrxn3

neurexin III

chr17_+_32993123 0.035 ENSMUST00000087666.4
ENSMUST00000157017.1
 Zfp952

zinc finger protein 952

chr15_-_100422991 0.025 ENSMUST00000138843.1
ENSMUST00000023774.5
 Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 2.2 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.2 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)