Motif ID: Zbtb6

Z-value: 0.792


Transcription factors associated with Zbtb6:

Gene SymbolEntrez IDGene Name
Zbtb6 ENSMUSG00000066798.3 Zbtb6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37443096_37443178-0.291.4e-01Click!


Activity profile for motif Zbtb6.

activity profile for motif Zbtb6


Sorted Z-values histogram for motif Zbtb6

Sorted Z-values for motif Zbtb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb6

PNG image of the network

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Top targets:


Showing 1 to 20 of 199 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_66981279 3.840 ENSMUST00000162098.2
 Shox2
short stature homeobox 2
chr17_+_47410247 3.484 ENSMUST00000177586.1
 Gm5814
predicted pseudogene 5814
chr5_+_36796228 2.900 ENSMUST00000181278.1
 Gm26605
predicted gene, 26605
chr11_-_102897123 2.874 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr12_-_83951355 2.549 ENSMUST00000181399.1
 Gm26571
predicted gene, 26571
chr1_-_133131782 2.254 ENSMUST00000180528.1
 Gm26616
predicted gene, 26616
chr11_-_102897146 2.015 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr11_-_42182924 1.963 ENSMUST00000020707.5
ENSMUST00000132971.1
 Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr10_-_80260959 1.941 ENSMUST00000020359.6
 Gamt
guanidinoacetate methyltransferase
chr3_+_54156039 1.926 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr5_+_135806859 1.811 ENSMUST00000126232.1
 Srrm3
serine/arginine repetitive matrix 3
chr10_-_80261004 1.796 ENSMUST00000105363.1
 Gamt
guanidinoacetate methyltransferase
chr10_+_7589788 1.708 ENSMUST00000134346.1
ENSMUST00000019931.5
 Lrp11

low density lipoprotein receptor-related protein 11

chr6_+_114131229 1.697 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr10_+_7589885 1.633 ENSMUST00000130590.1
ENSMUST00000135907.1
 Lrp11

low density lipoprotein receptor-related protein 11

chr19_-_5457397 1.633 ENSMUST00000179549.1
 Ccdc85b
coiled-coil domain containing 85B
chr6_+_124997062 1.560 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein
chr12_-_57546121 1.549 ENSMUST00000044380.6
 Foxa1
forkhead box A1
chr18_+_37504264 1.524 ENSMUST00000052179.6
 Pcdhb20
protocadherin beta 20
chr11_+_101246405 1.492 ENSMUST00000122006.1
ENSMUST00000151830.1
 Ramp2

receptor (calcitonin) activity modifying protein 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.9 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.5 4.5 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
1.2 3.7 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 3.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.8 3.3 GO:0009414 response to water deprivation(GO:0009414)
0.2 2.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 2.5 GO:0008643 carbohydrate transport(GO:0008643)
0.2 2.0 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.5 1.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.5 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.2 1.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.2 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.0 GO:0016486 peptide hormone processing(GO:0016486)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 4.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 4.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.3 GO:0043235 receptor complex(GO:0043235)
0.0 3.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.9 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.1 1.2 GO:0070938 contractile ring(GO:0070938)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.2 GO:0034704 calcium channel complex(GO:0034704)
0.1 1.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 0.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.9 GO:0044301 climbing fiber(GO:0044301)
0.0 0.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 3.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 3.1 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.1 2.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 2.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.9 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.6 1.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.6 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.9 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)