Motif ID: Zbtb7b

Z-value: 0.979


Transcription factors associated with Zbtb7b:

Gene SymbolEntrez IDGene Name
Zbtb7b ENSMUSG00000028042.9 Zbtb7b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7bmm10_v2_chr3_-_89393294_893933780.321.1e-01Click!


Activity profile for motif Zbtb7b.

activity profile for motif Zbtb7b


Sorted Z-values histogram for motif Zbtb7b

Sorted Z-values for motif Zbtb7b



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7b

PNG image of the network

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Top targets:


Showing 1 to 20 of 196 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_105471481 3.853 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr10_+_84756055 3.430 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr5_+_139543889 3.322 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr17_+_85620816 3.220 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr2_-_117342709 3.149 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr11_+_120948480 3.071 ENSMUST00000070653.6
Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr2_-_117342949 2.870 ENSMUST00000102534.4
Rasgrp1
RAS guanyl releasing protein 1
chr19_+_55742242 2.599 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr2_-_117342831 2.544 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr17_+_34592248 2.396 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr7_-_127122226 2.314 ENSMUST00000032912.5
Qprt
quinolinate phosphoribosyltransferase
chr11_+_108920800 2.211 ENSMUST00000140821.1
Axin2
axin2
chr8_-_87959560 2.178 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr14_-_70642268 2.008 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr5_+_137350371 1.893 ENSMUST00000166239.1
ENSMUST00000111054.1
Ephb4

Eph receptor B4

chr7_-_4752972 1.848 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr7_-_126799163 1.839 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr1_-_119053339 1.724 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr9_+_68653761 1.716 ENSMUST00000034766.7
Rora
RAR-related orphan receptor alpha
chr3_+_34649987 1.683 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 8.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.1 4.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 3.9 GO:0046785 microtubule polymerization(GO:0046785)
0.2 3.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 3.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.7 3.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.5 3.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.1 3.2 GO:0097402 neuroblast migration(GO:0097402)
0.3 2.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.6 2.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 2.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 2.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 2.0 GO:0008360 regulation of cell shape(GO:0008360)
0.5 1.9 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 1.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 1.7 GO:0060032 notochord regression(GO:0060032)
0.2 1.7 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.2 1.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.7 GO:0000920 cell separation after cytokinesis(GO:0000920)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 3.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 2.9 GO:0005667 transcription factor complex(GO:0005667)
0.3 2.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.2 GO:0005871 kinesin complex(GO:0005871)
0.1 1.8 GO:0030061 mitochondrial crista(GO:0030061)
0.3 1.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.7 GO:0097542 ciliary tip(GO:0097542)
0.0 1.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.6 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 8.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 8.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 6.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 3.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 3.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 3.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.9 GO:0016791 phosphatase activity(GO:0016791)
0.0 2.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 2.2 GO:0003777 microtubule motor activity(GO:0003777)
0.7 2.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.7 GO:0035198 miRNA binding(GO:0035198)
0.5 1.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.2 1.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)