Motif ID: Zfhx3
Z-value: 0.746
Transcription factors associated with Zfhx3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zfhx3 | ENSMUSG00000038872.8 | Zfhx3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfhx3 | mm10_v2_chr8_+_108714644_108714644 | -0.40 | 4.1e-02 | Click! |
Top targets:
Showing 1 to 20 of 87 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 35 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.8 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.0 | 2.0 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.1 | 1.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 1.8 | GO:0019882 | antigen processing and presentation(GO:0019882) |
| 0.1 | 1.7 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 1.7 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.3 | 1.4 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 1.1 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.0 | 1.1 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.3 | 1.0 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.3 | 1.0 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.0 | 0.9 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 0.0 | 0.9 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.8 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 0.8 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.1 | 0.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 0.7 | GO:0032929 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.7 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 0.5 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
Gene overrepresentation in cellular_component category:
Showing 1 to 13 of 13 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 1.8 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 1.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 1.4 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 1.4 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.2 | 1.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 1.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 0.7 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.1 | 0.7 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.4 | GO:0045275 | respiratory chain complex III(GO:0045275) |
| 0.0 | 0.2 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.0 | 0.1 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 26 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 1.8 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 1.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.6 | 1.7 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 0.1 | 1.7 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 1.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 1.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 1.4 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.2 | 1.0 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 1.0 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 0.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 0.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 0.4 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.1 | 0.4 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.3 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
