Motif ID: Zfp219_Zfp740

Z-value: 0.879

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp740mm10_v2_chr15_+_102203639_1022037090.442.4e-02Click!
Zfp219mm10_v2_chr14_-_52020698_520207370.394.7e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_29984219 3.425 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr6_+_120666388 3.003 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr17_-_70851189 2.971 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chrX_-_38564519 2.521 ENSMUST00000016681.8
Cul4b
cullin 4B
chr4_+_65124174 2.476 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chrX_+_42149534 2.193 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr10_-_127341583 2.094 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr8_-_87959560 2.063 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr12_+_53248677 2.013 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr4_-_134018829 1.984 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr19_-_59170978 1.981 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr3_-_89393294 1.971 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr3_+_41564880 1.864 ENSMUST00000168086.1
Phf17
PHD finger protein 17
chr17_+_85620816 1.860 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr3_+_95929246 1.851 ENSMUST00000165307.1
ENSMUST00000015893.6
Anp32e

acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

chr2_-_119477613 1.831 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr2_+_31640037 1.766 ENSMUST00000113470.2
Prdm12
PR domain containing 12
chr3_+_95929325 1.745 ENSMUST00000171368.1
ENSMUST00000168106.1
Anp32e

acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

chr4_-_3938354 1.732 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr18_+_82914632 1.720 ENSMUST00000071233.6
Zfp516
zinc finger protein 516

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 220 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 6.8 GO:0060746 parental behavior(GO:0060746)
0.5 5.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 4.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 4.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.7 3.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 3.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.3 2.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 2.8 GO:0001842 neural fold formation(GO:0001842)
0.3 2.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.8 2.3 GO:0097402 neuroblast migration(GO:0097402)
0.0 2.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.5 2.1 GO:0060032 notochord regression(GO:0060032)
0.2 2.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.1 GO:0021542 dentate gyrus development(GO:0021542)
0.1 2.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 2.1 GO:0051384 response to glucocorticoid(GO:0051384)
0.5 2.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 2.0 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.1 2.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 2.0 GO:0051028 mRNA transport(GO:0051028)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.6 GO:0005667 transcription factor complex(GO:0005667)
0.9 3.5 GO:0090537 CERF complex(GO:0090537)
0.0 3.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 3.3 GO:0005844 polysome(GO:0005844)
0.1 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.6 GO:0032993 protein-DNA complex(GO:0032993)
0.4 2.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 2.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 2.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.3 GO:0010369 chromocenter(GO:0010369)
0.2 2.1 GO:0097542 ciliary tip(GO:0097542)
0.2 2.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 1.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.8 GO:0031011 Ino80 complex(GO:0031011)
0.4 1.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.4 1.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 148 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.1 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 4.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.2 4.6 GO:0070410 co-SMAD binding(GO:0070410)
0.2 4.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 4.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 4.2 GO:0070888 E-box binding(GO:0070888)
0.3 3.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 3.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 3.3 GO:0001047 core promoter binding(GO:0001047)
0.2 3.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.3 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.2 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.2 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 2.0 GO:1990188 euchromatin binding(GO:1990188)
0.0 2.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.8 GO:0035198 miRNA binding(GO:0035198)