Motif ID: Zfp423

Z-value: 0.614


Transcription factors associated with Zfp423:

Gene SymbolEntrez IDGene Name
Zfp423 ENSMUSG00000045333.9 Zfp423

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp423mm10_v2_chr8_-_87804411_87804463-0.376.6e-02Click!


Activity profile for motif Zfp423.

activity profile for motif Zfp423


Sorted Z-values histogram for motif Zfp423

Sorted Z-values for motif Zfp423



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp423

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_29253001 3.092 ENSMUST00000071201.4
 Ntng2
netrin G2
chr2_+_180499893 2.462 ENSMUST00000029084.2
 Ntsr1
neurotensin receptor 1
chr14_+_119138415 2.255 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr4_+_42917234 2.180 ENSMUST00000107976.2
ENSMUST00000069184.2
 N28178

expressed sequence N28178

chr1_-_51941261 1.895 ENSMUST00000097103.3
 Gm8420
predicted gene 8420
chr7_-_70360593 1.777 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_-_147085445 1.601 ENSMUST00000067020.2
 Nkx2-4
NK2 homeobox 4
chr10_+_13966268 1.559 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr15_-_78718113 1.476 ENSMUST00000088592.4
 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr6_+_110645572 1.422 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr12_+_102948843 1.267 ENSMUST00000101099.5
 Unc79
unc-79 homolog (C. elegans)
chr15_-_66286224 1.232 ENSMUST00000070256.7
 Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr5_-_22344690 1.100 ENSMUST00000062372.7
ENSMUST00000161356.1
 Reln

reelin

chr5_-_135934590 1.043 ENSMUST00000055808.5
 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr7_+_29307924 1.040 ENSMUST00000108230.1
ENSMUST00000065181.5
 Dpf1

D4, zinc and double PHD fingers family 1

chr7_-_105633525 1.038 ENSMUST00000153371.1
ENSMUST00000106789.1
ENSMUST00000057525.7
 Trim3


tripartite motif-containing 3


chr12_-_14152038 1.019 ENSMUST00000020926.6
 Fam84a
family with sequence similarity 84, member A
chr14_+_70553687 1.017 ENSMUST00000161069.1
 Hr
hairless
chr8_+_58912257 0.947 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr7_-_105633479 0.907 ENSMUST00000147044.1
ENSMUST00000106791.1
 Trim3

tripartite motif-containing 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.5 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.4 2.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 1.8 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 1.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 1.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.3 1.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.2 1.1 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.8 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.7 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 0.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 0.6 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.4 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.6 2.5 GO:0032280 symmetric synapse(GO:0032280)
0.2 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 2.3 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.2 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.5 1.4 GO:0070905 serine binding(GO:0070905)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)