Motif ID: Zic4

Z-value: 0.963


Transcription factors associated with Zic4:

Gene SymbolEntrez IDGene Name
Zic4 ENSMUSG00000036972.8 Zic4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic4mm10_v2_chr9_+_91378636_91378646-0.366.8e-02Click!


Activity profile for motif Zic4.

activity profile for motif Zic4


Sorted Z-values histogram for motif Zic4

Sorted Z-values for motif Zic4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_180499893 4.200 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr4_+_141368116 3.468 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr14_-_64455903 3.172 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr4_+_152338619 2.908 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr9_-_29412204 2.884 ENSMUST00000115237.1
Ntm
neurotrimin
chr4_+_152338887 2.852 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr6_+_141524379 2.818 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr19_+_4855129 2.598 ENSMUST00000119694.1
Ctsf
cathepsin F
chr17_+_46297917 2.541 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr4_-_64046925 2.515 ENSMUST00000107377.3
Tnc
tenascin C
chr1_-_43163891 2.504 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr19_-_57008187 2.386 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr7_-_47133684 2.311 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr5_-_139325616 2.240 ENSMUST00000110865.1
Adap1
ArfGAP with dual PH domains 1
chr11_+_98741805 2.150 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr7_-_47133395 2.079 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr14_-_29721835 2.076 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr11_+_5861886 1.990 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr6_+_99692679 1.990 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr17_-_29237759 1.990 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr2_-_152951456 1.896 ENSMUST00000123121.2
Dusp15
dual specificity phosphatase-like 15
chr19_+_4099998 1.840 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr7_-_16476765 1.830 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr11_+_98741871 1.764 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr8_-_83166170 1.652 ENSMUST00000098605.2
Gm10645
predicted gene 10645
chr19_-_6235804 1.629 ENSMUST00000025695.9
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr1_+_91179822 1.613 ENSMUST00000097648.4
ENSMUST00000165855.1
Ramp1

receptor (calcitonin) activity modifying protein 1

chr15_+_99224976 1.474 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chrX_+_73503074 1.436 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr4_+_130792513 1.434 ENSMUST00000070478.3
Sdc3
syndecan 3
chr2_+_180598219 1.398 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr17_+_37045963 1.376 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr10_+_106470281 1.339 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr15_-_33687840 1.301 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr2_+_147187424 1.288 ENSMUST00000144411.1
6430503K07Rik
RIKEN cDNA 6430503K07 gene
chr4_-_129121234 1.203 ENSMUST00000030572.3
Hpca
hippocalcin
chr2_-_29253001 1.184 ENSMUST00000071201.4
Ntng2
netrin G2
chr4_-_129121699 1.166 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr7_+_27653906 1.161 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr2_-_152951547 1.155 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr7_+_28458658 1.145 ENSMUST00000108288.3
ENSMUST00000055110.9
Lrfn1

leucine rich repeat and fibronectin type III domain containing 1

chr11_+_121702591 1.132 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr11_+_24076529 1.107 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr11_+_46055973 1.077 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr2_+_131909928 1.068 ENSMUST00000091288.6
Prnp
prion protein
chr6_-_59426279 1.060 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr6_-_35308110 1.043 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr12_-_57546121 1.041 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr3_-_110142996 1.000 ENSMUST00000156177.2
Ntng1
netrin G1
chr8_-_64849818 0.999 ENSMUST00000034017.7
Klhl2
kelch-like 2, Mayven
chr9_-_107710475 0.993 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr17_-_26508463 0.962 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr2_+_131909951 0.947 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr7_+_28766747 0.944 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr7_+_27591513 0.942 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr5_-_113310697 0.942 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr2_-_152951688 0.937 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr11_-_71033462 0.937 ENSMUST00000156068.2
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr11_-_78497458 0.909 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr19_+_47178820 0.907 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr9_+_58554799 0.906 ENSMUST00000098676.2
Gm10657
predicted gene 10657
chr11_+_57801575 0.902 ENSMUST00000020826.5
Sap30l
SAP30-like
chr2_+_164879358 0.900 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr4_+_42158092 0.893 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr5_-_113310729 0.892 ENSMUST00000112325.1
ENSMUST00000048112.6
Sgsm1

small G protein signaling modulator 1

chr1_-_21961581 0.886 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr17_-_34031644 0.883 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr2_+_120977017 0.874 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr7_+_139834148 0.866 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr16_+_20733104 0.863 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr4_+_104367549 0.853 ENSMUST00000106830.2
Dab1
disabled 1
chr17_-_34031544 0.841 ENSMUST00000025186.8
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr17_-_45549655 0.839 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr11_-_78497734 0.820 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr1_+_75546449 0.809 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr17_+_37045980 0.807 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_+_48206025 0.797 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr6_+_47877204 0.788 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr17_-_34031684 0.757 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr9_+_108460518 0.749 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr10_-_81365807 0.748 ENSMUST00000020456.4
4930404N11Rik
RIKEN cDNA 4930404N11 gene
chr14_-_54913089 0.746 ENSMUST00000050772.7
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr9_-_35558522 0.706 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr6_+_65671590 0.683 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr11_-_101171302 0.663 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr8_+_107031218 0.658 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr7_-_143460989 0.636 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr9_-_89622986 0.624 ENSMUST00000044491.6
AF529169
cDNA sequence AF529169
chr4_+_129513581 0.623 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr7_-_70360593 0.622 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr11_-_102946688 0.610 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr7_-_25297866 0.598 ENSMUST00000148150.1
ENSMUST00000155118.1
Pafah1b3

platelet-activating factor acetylhydrolase, isoform 1b, subunit 3

chr15_+_74563738 0.574 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr17_-_83631892 0.570 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr7_+_27591705 0.560 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr7_-_25297967 0.556 ENSMUST00000005583.5
Pafah1b3
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr5_-_134688568 0.552 ENSMUST00000015137.3
Limk1
LIM-domain containing, protein kinase
chr7_-_16286744 0.516 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr5_-_142509653 0.507 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chr6_-_115251839 0.491 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr8_+_72240315 0.478 ENSMUST00000126885.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr12_+_24651346 0.477 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr2_-_167062607 0.474 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr19_+_5447692 0.470 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr2_-_167062981 0.464 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr7_+_45872772 0.461 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr9_+_65346066 0.459 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chr2_+_85136355 0.457 ENSMUST00000057019.7
Aplnr
apelin receptor
chr11_-_85139939 0.452 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr7_-_57387172 0.449 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr7_+_45873127 0.447 ENSMUST00000107718.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr2_-_130642770 0.443 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr13_-_48625571 0.442 ENSMUST00000035824.9
Ptpdc1
protein tyrosine phosphatase domain containing 1
chr2_+_164960809 0.442 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr19_-_12501996 0.439 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr6_-_97487801 0.438 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr17_-_29347902 0.428 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr4_+_117096049 0.426 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr10_-_61979073 0.396 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr4_-_62360436 0.392 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr7_-_97579382 0.386 ENSMUST00000151840.1
ENSMUST00000135998.1
ENSMUST00000144858.1
ENSMUST00000146605.1
ENSMUST00000072725.5
ENSMUST00000138060.1
ENSMUST00000154853.1
ENSMUST00000136757.1
ENSMUST00000124552.1
Aamdc








adipogenesis associated Mth938 domain containing








chr2_-_181288016 0.382 ENSMUST00000049032.6
Gmeb2
glucocorticoid modulatory element binding protein 2
chr15_-_97831460 0.380 ENSMUST00000079838.7
ENSMUST00000118294.1
Hdac7

histone deacetylase 7

chr12_-_67222549 0.375 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr2_-_73775341 0.366 ENSMUST00000112024.3
ENSMUST00000166199.1
ENSMUST00000180045.1
Chn1


chimerin (chimaerin) 1


chr2_+_91922178 0.360 ENSMUST00000170432.1
Chrm4
cholinergic receptor, muscarinic 4
chr17_-_57059795 0.345 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chrX_-_49797700 0.344 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr3_+_107595031 0.343 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr18_-_24603791 0.333 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr4_-_62360524 0.332 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chrX_+_85574018 0.325 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr17_+_83706170 0.321 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr19_-_4477447 0.320 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr4_-_24851079 0.319 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr11_+_75732869 0.309 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr7_-_34654342 0.308 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr8_+_72240018 0.305 ENSMUST00000003117.8
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr11_+_75733037 0.299 ENSMUST00000131398.1
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr5_+_43233463 0.298 ENSMUST00000169035.1
ENSMUST00000166713.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chrX_-_7740206 0.288 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr8_-_64693027 0.286 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr17_+_26113286 0.274 ENSMUST00000025010.7
Tmem8
transmembrane protein 8 (five membrane-spanning domains)
chr18_-_77565050 0.269 ENSMUST00000182153.1
ENSMUST00000182146.1
ENSMUST00000026494.7
ENSMUST00000182024.1
Rnf165



ring finger protein 165



chr18_-_24603464 0.265 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr2_+_32151074 0.223 ENSMUST00000036691.7
ENSMUST00000069817.8
Prrc2b

proline-rich coiled-coil 2B

chr17_+_79051906 0.218 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr17_-_71310952 0.200 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr11_-_70687917 0.180 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr4_-_156197479 0.179 ENSMUST00000075787.6
ENSMUST00000180572.1
Agrn

agrin

chr7_-_98119482 0.177 ENSMUST00000138627.1
ENSMUST00000107127.1
ENSMUST00000107128.1
Myo7a


myosin VIIA


chr10_+_127380591 0.166 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr6_-_39118211 0.156 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr12_-_12941827 0.156 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_-_167661496 0.151 ENSMUST00000125544.2
ENSMUST00000006587.6
Gm20431
Tmem189
predicted gene 20431
transmembrane protein 189
chr6_-_83054415 0.149 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr8_+_87472838 0.147 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr9_+_46012810 0.147 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr2_-_153529941 0.136 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr2_+_156065180 0.133 ENSMUST00000038860.5
Spag4
sperm associated antigen 4
chrX_-_74085586 0.124 ENSMUST00000123362.1
ENSMUST00000140399.1
ENSMUST00000100750.3
Mecp2


methyl CpG binding protein 2


chr7_+_45570342 0.122 ENSMUST00000120864.1
Bcat2
branched chain aminotransferase 2, mitochondrial
chr4_-_151996113 0.119 ENSMUST00000055688.9
Phf13
PHD finger protein 13
chr10_+_127380799 0.118 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr13_-_95223045 0.105 ENSMUST00000162292.1
Pde8b
phosphodiesterase 8B
chr19_+_6975048 0.104 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_+_71364901 0.103 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr13_-_37994111 0.099 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr11_-_115536181 0.097 ENSMUST00000118155.1
ENSMUST00000153892.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)

chr9_-_58555129 0.093 ENSMUST00000165365.1
Cd276
CD276 antigen
chr1_+_87853264 0.087 ENSMUST00000027517.7
Dgkd
diacylglycerol kinase, delta
chr18_-_80713062 0.075 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chrX_-_107403295 0.053 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr11_-_87987528 0.053 ENSMUST00000020775.2
Dynll2
dynein light chain LC8-type 2
chr17_-_45593626 0.047 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr18_+_56707725 0.044 ENSMUST00000025486.8
Lmnb1
lamin B1
chr1_-_180813534 0.041 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr11_-_69920892 0.034 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr11_-_115535804 0.029 ENSMUST00000117589.1
ENSMUST00000121185.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)

chr9_-_105495037 0.028 ENSMUST00000176190.1
ENSMUST00000163879.2
ENSMUST00000112558.2
ENSMUST00000176390.1
Atp2c1



ATPase, Ca++-sequestering



chr4_+_148130883 0.024 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr11_-_70669283 0.007 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7

sperm associated antigen 7

chr11_+_93099284 0.006 ENSMUST00000092780.3
ENSMUST00000107863.2
Car10

carbonic anhydrase 10

chr3_+_97658212 0.004 ENSMUST00000045743.6
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.2 5.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.1 4.2 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.9 4.4 GO:2001025 positive regulation of response to drug(GO:2001025)
0.8 2.4 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.7 2.0 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.6 3.2 GO:0030091 protein repair(GO:0030091)
0.6 2.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.4 1.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.3 1.0 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.3 1.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.3 1.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.3 2.2 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.3 0.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 2.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.9 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2 1.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.7 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.6 GO:0061743 motor learning(GO:0061743)
0.2 0.9 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.0 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.7 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 1.8 GO:0042711 maternal behavior(GO:0042711)
0.1 3.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 1.5 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.6 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.7 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 2.0 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.8 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.0 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.0 0.5 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.6 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.8 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 1.0 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 3.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.2 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 2.1 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.0 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0032280 symmetric synapse(GO:0032280)
0.7 4.4 GO:1990635 proximal dendrite(GO:1990635)
0.4 2.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 2.4 GO:0044327 dendritic spine head(GO:0044327)
0.2 1.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 1.0 GO:0005902 microvillus(GO:0005902)
0.2 4.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.9 GO:0033010 paranodal junction(GO:0033010)
0.2 2.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.6 GO:0044301 climbing fiber(GO:0044301)
0.1 2.5 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0090543 Flemming body(GO:0090543)
0.1 1.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0033391 chromatoid body(GO:0033391)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0098984 neuron to neuron synapse(GO:0098984)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.7 2.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 3.4 GO:0045545 syndecan binding(GO:0045545)
0.4 1.6 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.4 1.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 3.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 0.9 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.2 0.9 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 4.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 2.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.1 3.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 5.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 4.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0043023 GTPase inhibitor activity(GO:0005095) ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0015301 anion:anion antiporter activity(GO:0015301)