Motif ID: Zkscan1

Z-value: 0.583


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.125.6e-01Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

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Top targets:


Showing 1 to 20 of 127 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_83779999 2.585 ENSMUST00000046168.5
 Mpped1
metallophosphoesterase domain containing 1
chr1_-_56969864 1.921 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr8_+_72646679 1.453 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1

chr15_-_79164477 1.344 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr8_+_72646728 1.258 ENSMUST00000161254.1
 Nwd1
NACHT and WD repeat domain containing 1
chr1_-_56969827 1.055 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_+_171840607 1.031 ENSMUST00000136479.1
ENSMUST00000042302.6
 Cd84

CD84 antigen

chr7_+_112225856 0.995 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr3_+_62338344 0.968 ENSMUST00000079300.6
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr14_-_30353468 0.960 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr19_-_61228396 0.945 ENSMUST00000076046.6
 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr11_+_19924403 0.732 ENSMUST00000093298.5
 Spred2
sprouty-related, EVH1 domain containing 2
chr11_+_19924354 0.723 ENSMUST00000093299.6
 Spred2
sprouty-related, EVH1 domain containing 2
chr15_-_78572754 0.584 ENSMUST00000043214.6
 Rac2
RAS-related C3 botulinum substrate 2
chr19_-_45742873 0.580 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr5_-_70842617 0.575 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr5_-_8367982 0.568 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
 Adam22






a disintegrin and metallopeptidase domain 22






chr10_+_86300372 0.542 ENSMUST00000020234.7
 Timp3
tissue inhibitor of metalloproteinase 3
chr2_-_27248335 0.538 ENSMUST00000139312.1
 Sardh
sarcosine dehydrogenase
chr5_+_64812336 0.505 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 1.3 GO:0032808 lacrimal gland development(GO:0032808) enteric nervous system development(GO:0048484)
0.3 1.0 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.3 1.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 0.6 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.6 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 1.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.3 GO:0001527 microfibril(GO:0001527)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.2 1.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 1.0 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.0 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 0.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.6 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 0.5 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)