Motif ID: Zkscan3

Z-value: 0.314


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.618.9e-04Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Showing 1 to 20 of 63 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_61105844 0.811 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr6_-_122856151 0.700 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr5_+_24985840 0.621 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr11_-_75422524 0.563 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr11_-_75422586 0.510 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr2_+_155775333 0.490 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr8_+_70616816 0.490 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr1_-_40790642 0.465 ENSMUST00000039672.5
 Mfsd9
major facilitator superfamily domain containing 9
chr13_+_42709482 0.400 ENSMUST00000066928.5
ENSMUST00000148891.1
 Phactr1

phosphatase and actin regulator 1

chr6_+_125552948 0.396 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr7_-_98178254 0.386 ENSMUST00000040971.7
 Capn5
calpain 5
chr2_+_32646586 0.385 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr2_+_156613664 0.381 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr8_-_105758570 0.376 ENSMUST00000155038.2
ENSMUST00000013294.9
 Gfod2

glucose-fructose oxidoreductase domain containing 2

chr18_+_82554463 0.318 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
 Mbp










myelin basic protein










chr11_-_102365111 0.300 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr8_-_124897685 0.284 ENSMUST00000098312.2
 Exoc8
exocyst complex component 8
chr5_-_73338580 0.281 ENSMUST00000087195.5
 Ociad2
OCIA domain containing 2
chr8_+_94810446 0.260 ENSMUST00000034232.1
 Ccl17
chemokine (C-C motif) ligand 17
chr11_+_116918844 0.256 ENSMUST00000103027.3
 Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 0.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.5 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0015701 response to activity(GO:0014823) bicarbonate transport(GO:0015701) response to arsenic-containing substance(GO:0046685)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0043203 axon hillock(GO:0043203)
0.3 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0019955 cytokine binding(GO:0019955)
0.2 0.7 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.5 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)