Motif ID: Zscan4c

Z-value: 1.146


Transcription factors associated with Zscan4c:

Gene SymbolEntrez IDGene Name
Zscan4c ENSMUSG00000054272.5 Zscan4c



Activity profile for motif Zscan4c.

activity profile for motif Zscan4c


Sorted Z-values histogram for motif Zscan4c

Sorted Z-values for motif Zscan4c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zscan4c

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_130936172 7.414 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr4_-_46991842 6.940 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_55681257 6.416 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr8_+_118283719 6.222 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr16_+_45094036 5.445 ENSMUST00000061050.5
 Ccdc80
coiled-coil domain containing 80
chr15_-_78718113 4.872 ENSMUST00000088592.4
 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr4_+_49059256 4.790 ENSMUST00000076670.2
 E130309F12Rik
RIKEN cDNA E130309F12 gene
chr2_-_36105271 4.335 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr9_+_26733728 3.850 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
 B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr9_-_49798905 3.809 ENSMUST00000114476.2
 Ncam1
neural cell adhesion molecule 1
chr9_-_49798729 3.804 ENSMUST00000166811.2
 Ncam1
neural cell adhesion molecule 1
chr14_-_60177482 3.424 ENSMUST00000140924.1
 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_+_89909775 3.371 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr3_-_158562199 3.358 ENSMUST00000106044.1
 Lrrc7
leucine rich repeat containing 7
chr5_-_44799643 3.184 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr13_+_58807884 3.027 ENSMUST00000079828.5
 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr18_-_23041641 2.820 ENSMUST00000097651.3
 Nol4
nucleolar protein 4
chr9_+_26733845 2.719 ENSMUST00000115269.2
 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr10_+_43579161 2.604 ENSMUST00000058714.8
 Cd24a
CD24a antigen
chr4_+_123183722 2.584 ENSMUST00000152194.1
 Hpcal4
hippocalcin-like 4
chr19_-_28963863 2.530 ENSMUST00000161813.1
 4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr7_-_47132698 2.525 ENSMUST00000033142.5
 Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr9_+_57940104 2.421 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr4_-_87806276 2.247 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_+_16257706 2.228 ENSMUST00000109645.2
ENSMUST00000109647.2
 Vstm2a

V-set and transmembrane domain containing 2A

chr4_-_45530330 2.042 ENSMUST00000061986.5
 Shb
src homology 2 domain-containing transforming protein B
chr10_-_42276688 2.022 ENSMUST00000175881.1
ENSMUST00000056974.3
 Foxo3

forkhead box O3

chr19_+_28963892 1.969 ENSMUST00000045674.2
 Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr9_+_21936986 1.921 ENSMUST00000046371.6
 BC018242
cDNA sequence BC018242
chr8_-_95142477 1.907 ENSMUST00000034240.7
ENSMUST00000169748.1
 Kifc3

kinesin family member C3

chr7_-_98178254 1.816 ENSMUST00000040971.7
 Capn5
calpain 5
chr10_+_81292961 1.805 ENSMUST00000163075.1
ENSMUST00000105327.3
ENSMUST00000045469.8
 Pip5k1c


phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma


chr16_-_38713235 1.795 ENSMUST00000023487.4
 Arhgap31
Rho GTPase activating protein 31
chr10_-_42276744 1.765 ENSMUST00000105502.1
ENSMUST00000105501.1
 Foxo3

forkhead box O3

chr4_-_87806296 1.641 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr13_-_56296551 1.630 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr5_-_145201829 1.570 ENSMUST00000162220.1
ENSMUST00000031632.8
 Zkscan14

zinc finger with KRAB and SCAN domains 14

chr3_-_107760221 1.556 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr5_+_27261916 1.378 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr2_-_91182848 1.347 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
 Madd


MAP-kinase activating death domain


chr7_-_119184374 1.291 ENSMUST00000084650.4
 Gpr139
G protein-coupled receptor 139
chr2_+_68861564 1.242 ENSMUST00000176018.1
 Cers6
ceramide synthase 6
chr4_+_123183456 1.167 ENSMUST00000126995.1
 Hpcal4
hippocalcin-like 4
chr8_-_48555846 1.143 ENSMUST00000110345.1
ENSMUST00000110343.1
 Tenm3

teneurin transmembrane protein 3

chr9_-_44799179 1.136 ENSMUST00000114705.1
ENSMUST00000002100.7
 Tmem25

transmembrane protein 25

chrX_+_48519245 1.130 ENSMUST00000033430.2
 Rab33a
RAB33A, member of RAS oncogene family
chr15_-_37458523 1.127 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chrX_+_161717498 1.125 ENSMUST00000061514.7
 Rai2
retinoic acid induced 2
chr19_+_8664005 1.121 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr1_+_132191436 1.121 ENSMUST00000112357.2
 Lemd1
LEM domain containing 1
chr14_-_70627008 1.098 ENSMUST00000110984.2
 Dmtn
dematin actin binding protein
chr8_+_117257019 1.089 ENSMUST00000166750.1
 Cmip
c-Maf inducing protein
chr10_+_74967164 1.067 ENSMUST00000037813.4
 Gnaz
guanine nucleotide binding protein, alpha z subunit
chr2_+_68861433 0.935 ENSMUST00000028426.2
 Cers6
ceramide synthase 6
chr3_-_108017806 0.920 ENSMUST00000126593.1
 Gstm1
glutathione S-transferase, mu 1
chr2_-_116064512 0.876 ENSMUST00000074285.6
 Meis2
Meis homeobox 2
chr2_-_116064721 0.854 ENSMUST00000110906.2
 Meis2
Meis homeobox 2
chr9_+_36832684 0.798 ENSMUST00000034630.8
 Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_-_116065047 0.777 ENSMUST00000028639.6
ENSMUST00000102538.4
 Meis2

Meis homeobox 2

chr12_-_69892989 0.732 ENSMUST00000110567.1
ENSMUST00000171211.1
 Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr2_-_63184253 0.718 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr11_-_101785252 0.570 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_-_50739365 0.548 ENSMUST00000117093.1
ENSMUST00000121634.1
 Dixdc1

DIX domain containing 1

chr2_+_30364262 0.518 ENSMUST00000142801.1
ENSMUST00000100214.3
 Fam73b

family with sequence similarity 73, member B

chr5_-_128953303 0.504 ENSMUST00000111346.1
 Rimbp2
RIMS binding protein 2
chr12_-_112929415 0.470 ENSMUST00000075827.3
 Jag2
jagged 2
chr10_-_78295394 0.467 ENSMUST00000105387.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr15_+_80173642 0.464 ENSMUST00000044970.6
 Mgat3
mannoside acetylglucosaminyltransferase 3
chr6_-_122340200 0.376 ENSMUST00000159384.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr17_+_78508063 0.373 ENSMUST00000024880.9
 Vit
vitrin
chr4_-_116464151 0.368 ENSMUST00000106486.1
ENSMUST00000106485.1
 Mast2

microtubule associated serine/threonine kinase 2

chr2_+_30364227 0.285 ENSMUST00000077977.7
ENSMUST00000140075.2
 Fam73b

family with sequence similarity 73, member B

chr18_-_79109391 0.279 ENSMUST00000025430.8
ENSMUST00000161465.2
 Setbp1

SET binding protein 1

chr15_-_85578070 0.279 ENSMUST00000109424.2
 Wnt7b
wingless-related MMTV integration site 7B
chr19_-_21472552 0.262 ENSMUST00000087600.3
 Gda
guanine deaminase
chr11_-_70237638 0.195 ENSMUST00000100950.3
 0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr19_+_53310495 0.188 ENSMUST00000003870.7
 Mxi1
Max interacting protein 1
chr11_-_70237886 0.138 ENSMUST00000108577.1
ENSMUST00000108579.1
ENSMUST00000021181.6
ENSMUST00000108578.2
ENSMUST00000102569.3
 0610010K14Rik




RIKEN cDNA 0610010K14 gene




chr5_+_114896936 0.136 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
 Oasl2


2'-5' oligoadenylate synthetase-like 2


chr16_+_4756845 0.131 ENSMUST00000140367.1
ENSMUST00000118885.1
ENSMUST00000121529.1
 Hmox2


heme oxygenase (decycling) 2


chr10_+_118860826 0.117 ENSMUST00000059966.4
 4932442E05Rik
RIKEN cDNA 4932442E05 gene
chr16_-_37384940 0.100 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr2_+_169633517 0.067 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr8_+_82863351 0.062 ENSMUST00000078525.5
 Rnf150
ring finger protein 150
chr10_-_79766872 0.053 ENSMUST00000047203.8
 Rnf126
ring finger protein 126
chr6_-_122340499 0.023 ENSMUST00000160843.1
 Phc1
polyhomeotic-like 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.6 6.2 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
1.2 7.4 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.9 2.6 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.7 4.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.5 1.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.5 3.8 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.5 1.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.5 2.5 GO:2001025 positive regulation of response to drug(GO:2001025)
0.5 3.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.5 3.4 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 1.3 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.4 2.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.4 3.9 GO:0007379 segment specification(GO:0007379)
0.4 1.1 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.3 6.4 GO:0021542 dentate gyrus development(GO:0021542)
0.3 6.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 1.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 2.0 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.3 6.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 3.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 0.6 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.3 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) chemoattraction of axon(GO:0061642) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.1 0.3 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 5.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.5 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 5.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 2.4 GO:0008542 visual learning(GO:0008542)
0.0 1.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.4 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 1.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.9 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 1.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 2.5 GO:1990635 proximal dendrite(GO:1990635)
0.4 5.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 2.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 0.8 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.2 1.9 GO:0005915 zonula adherens(GO:0005915)
0.2 3.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 16.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.4 GO:0043194 axon initial segment(GO:0043194)
0.1 3.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 3.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 5.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0055100 adiponectin binding(GO:0055100)
1.2 6.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.1 6.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 3.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 1.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.4 7.6 GO:0030275 LRR domain binding(GO:0030275)
0.3 7.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 2.4 GO:0038191 neuropilin binding(GO:0038191)
0.3 5.4 GO:0001968 fibronectin binding(GO:0001968)
0.2 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 3.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 2.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 4.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.9 GO:0016151 nickel cation binding(GO:0016151)
0.1 3.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 3.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 7.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.6 GO:0005126 cytokine receptor binding(GO:0005126)